Nova Science Publishers, 2016. — 101 p. Aminoglycosides are a commonly used class of antibiotic worldwide, with examples including gentamicin, tobramycin and amikacin. Their low cost, together with their effectiveness against Gram-negative organisms, including Pseudomonas aeruginosa, makes them a valuable tool in treating infections. In addition, aminoglycosides have...
CRC Press, 2016. — 133 p. The presence of antibiotics, antibiotic resistance genes, and antibiotic resistant bacteria in the environment (i.e., outside of clinical settings, such as antibiotic-treated patients or antibiotic-impregnated locations, such as hospitals) is a cause of growing worldwide concern, as it reveals the extensive impact of antibiotic abuse and other...
Wiley, 2007. — 339 p. Advances that open new avenues in developing aminoglycoside antibiotics. During the last twenty years, there have been numerous advances in the understanding of the chemistry, biochemistry, and recognition of aminoglycosides. This has led to the development of novel antibiotics and opened up new therapeutic targets for intervention. This is the first book...
AvE4EvA 2015. — 202 p. ISBN10: 953-51-2232-0. ISBN13: 978-953-51-2232-6. This edition is intended to provide better understanding of antibacterial drugs and their mechanism, the role of a few metal drug complexes as antibacterials, cross-checking of a few compounds and biomaterials against drug-resistant bacterial strains as well as a few alternative approaches using medicinal...
ASM Press, 2007. — 386 p. A vital, comprehensive overview from some of the world’s leading researchers and scholars in this field. Discusses bβ-Lactamases and aminoglycoside-modifying enzymes as well as other enzymatic mechanisms that result in resistance. Covers the different ways bacteria share resistance determinants, both vertically and horizontally. Offers strategies to...
Wiley, 2019. — 701 p. — ISBN: 978-1-119-28252-5 This book presents a thorough and authoritative overview of the multifaceted field of antibiotic science – offering guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases. Current Antibiotics and Their Mechanism of Action Resistance to Aminoglycosides: Glycomics and the Link to...
Nova Science Publishers, 2017. — 282 p. This book examines the synthesis, properties and biological activities of antibacterials. Chapter One focuses on the recent development of biomass antibacterials. Chapter Two provides comprehensive overview on smart materials based on structured noble metals covering its various forms from ultrathin layers over discrete metal islands up...
14th edition. — Jaypee Brothers Medical Publishers, 2015. — 803 p. Overview of antimicrobial therapy. Empiric therapy based on clinical syndrome antibiotic susceptibility profiles and initial therapy of isolates. Pending susceptibility results. Parasites, fungi, unusual organisms. HIV infection. Prophylaxis and immunizations. Pediatric infectious diseases and pediatric drug...
7th Edition. – Oxford University Press, UK, 2015. – 450 p. – ISBN: 0199689776. Antimicrobial agents are essential for the treatment of life-threatening infections and for managing the burden of minor infections in the community. In addition, they play a key role in organ and bone marrow transplantation, cancer chemotherapy, artificial joint and heart valve surgery. Unlike other...
FT Press, 2011 - 288 p. As pathogenic bacteria evolve, antibiotic resistance is spreading, compromising our ability to control and treat infectious diseases. Antibiotic Resistance thoroughly illuminates this crucial issue for healthcare professionals, researchers, students, and policymakers. Two leading investigators explain what resistance is, how it emerges, which human...
9th Edition. - Saunders Elsevier, 2010. - 913 p. - Well-respected and widely regarded as the most comprehensive text in the field, Antibiotic and Chemotherapy, 9th Edition by Drs. Finch, Greenwood, Whitley, and Norrby, provides globally relevant coverage of all types of antimicrobial agents used in human medicine, including all antiviral, antiprotozoan and anthelminthic agents....
The Royal Society of Chemistry, 2017. — 286 p. Recent years have seen a resurgence of antibiotic drug discovery. This book brings together the relevant information to assess the state-of-the-art. It identifies and elaborates the most recent and compelling strategies for antibiotic drug discovery with a primary focus on new targets, mechanisms and molecular entities. Addressing...
Springer, 2018. — 222 p. — (Topics in Medicinal Chemistry 26). — ISBN: 978-3-319-70838-6. Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new...
Springer, 2018. — 203 p. — (Topics in Medicinal Chemistry 25). — ISBN: 978-3-319-68096-5. Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new...
Springer, 2017. — 601 p. — ISBN10: 1493906933, ISBN13: 978-1493906932. This is a comprehensive tool covering all manifestations of antimicrobial resistance, with viral, bacterial, parasitical and fungal resistance each given a dedicated section. The underlining molecular mechanisms, which depend not only on the microbe, but on the specific drug (target), are highly diverse, and...
Wiley, 2014. - 575 p. - Most of the antibiotics now in use have been discovered more or less by chance, and their mechanisms of action have only been elucidated after their discovery. To meet the medical need for next-generation antibiotics, a more rational approach to antibiotic development is clearly needed. Opening with a general introduction about antimicrobial drugs, their...
Palgrave Macmillan, 2018 (2019 Edition). — 233 p. — ISBN10: 3319906550, 13 978-3319906553. Antimicrobial resistance (AMR) is predicted to be one of the greatest threats to public health in the twenty-first century. In this context, understanding the reasons why perceptions of antibiotic risk differ between different groups is crucial when it comes to tackling antibiotic misuse....
Palgrave Macmillan, 2018 (2019 Edition). — 199 p. — ISBN10: 3319906550, 13 978-3319906553. Antimicrobial resistance (AMR) is predicted to be one of the greatest threats to public health in the twenty-first century. In this context, understanding the reasons why perceptions of antibiotic risk differ between different groups is crucial when it comes to tackling antibiotic misuse....
Elsevier Science & Technology Books, 2016. — 436 p. Antibiotic Resistance: Mechanisms and New Antimicrobial Approaches discusses up-to-date knowledge in mechanisms of antibiotic resistance and all recent advances in fighting microbial resistance such as the applications of nanotechnology, plant products, bacteriophages, marine products, algae, insect-derived products, and other...
Nova Science Publishers, Inc., 2013. - 146 p. - Gentamicin is an aminoglycoside antibiotic naturally synthesized by Micromonospora, a Gram-positive genus of bacteria widely found in water and soil. This antibiotic is useful against a wide variety of bacteria, and works by binding the 30S subunit of the bacterial ribosome, which interrupts bacterial protein synthesis. In this...
Springer International Publishing AG, 2017. — 283 p. — ISBN: 9783319479606. Bacterial contamination is still an unresolved problem present in cases in which a biomaterial is required. This is an issue independent of the biomaterial considered and is particularly serious in those cases in which long-term implants are employed. In this context, polymers have been proposed as...
Caister Academic Press, 2015. - 450 p. - The 'golden age' for antibiotic discovery, from 1940 until the early 1970s, ushered in a new era in human- and animal-health and the associated dramatic increase in human life expectancies. Indeed the possibility of eradicating infectious disease seemed feasible. However it soon became apparent that microorganisms wouldn't be defeated so...
Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim 2009. — 509 p. ISBN: 978-3-527-32327-2 Addressing parasitic diseases and those caused by bacteria, this much needed reference and handbook provides a unique insight into the approach adopted by commercial science towards infectious diseases, including the work of medicinal chemists. Many of the authors are scientists with hands–on...
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