Humana Press, 2017. — 135 p. — (Cancer Drug Discovery and Development). — ISBN: 978-3-319-45395-8, 978-3-319-45397-2. Outlines how to recreate the tumor microenvironment, to culture primary tumors without the need for developmental priming factors, and to deliver targeted therapeutics in a manner that recapitulates pharmacokinetics in vivo Aids in understanding many aspects of...
Springer New York, 2014. — 61 p. With the rise of systems biology as an approach in biochemistry research, using high throughput techniques such as mass spectrometry to generate metabolic profiles of cancer metabolism is becoming increasingly popular. There are examples of cancer metabolic profiling studies in the academic literature; however they are often only in journals...
CRC Press, 2014. — 402 p. Cell signaling is a field that studies how cells communicate to control basic activities and respond to their environment. When looking specifically at cancer cells, researchers can gain a better understanding of cancer on a cellular level, an understanding that may have implications for developing new treatments. The current volume provides an...
Cham, Switzerland: Springer International Publishing, 2015. — 560 p. — ISBN: 978-3-319-21029-2, 978-3-319-21030-8. Introduces emerging concepts in cancer stem cell biology and advances our understanding of potential cancer stem cell-based approaches for the development of therapeutic strategies in oncology Provides a platform for cancer researchers to obtain new perspectives...
Springer, 2014. — 433 p. Aberrant expression and function of microRNAs (miRNAs) in cancer have added a new layer of complexity to the understanding of development and progression of the disease state. It has been demonstrated that miRNAs have a crucial function in oncogenesis by regulating cell proliferation and apoptosis as oncogenes or tumor suppressors. The expression...
Springer International Publishing, Switzerland, 2016. — 271 p. — (Energy Balance and Cancer 11). — ISBN: 978-3-319-41608-3, 978-3-319-41610-6. This volume of Energy Balance and Cancer provides state-of-the-art descriptions of the rapidly evolving science of epigenetics and how it may explain mechanisms by which alterations in energy balance such as obesity and physical activity...
Cham, Switzerland: Springer International Publishing, 2015. — 295 p. — (Energy Balance and Cancer 10). — ISBN: 978-3-319-16732-9, 978-3-319-16733-6. Provides compilation of major experimental mouse model systems for future preclinical research on energy balance and cancer Identifies how models are further enhanced by technology to identify DNA sequence changes that result in...
Springer, 2020. — 122 p. — (Advances in Experimental Medicine and Biology 1240). — ISBN: 978-3-030-38314-5. Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on the role of interleukins in the tumor microenvironment. Each chapter focuses on the various ways to target the tumor...
Chelsea House, 2007. — 112 p. Cancer Genetics demonstrates how cancer cells differ from normal cells in structure and function. It examines specific cancer-related genes, such as oncogenes and tumor suppressor genes, and discusses inherited syndromes that are associated with cancer, including certain forms of breast cancer. New research into the human genome and the possibility...
Chelsea House Publishers, 2007. — 136 p. Causes of Cancer delves into the many factors responsible for causing cancer, from environmental conditions to abnormal in vitro and in vivo developments to viruses and cancers caused by exposure to radiation. This richly informative book also empowers readers by highlighting how avoiding exposure to particular carcinogens may prevent...
Totowa, New Jersey: Humana Press, 2000. — 452 p. Hospital General of Granollers, Barcelona, Spain. Provides a look at the evolution of our knowledge of cancer. Emphasizes prevention, early diagnosis, prognosis, and treatment. For basic and clinical oncologists. Explains cancer as a 'disease process' involving key regulatory pathways. DNLM: Medical Oncology. Due diligence has...
3rd edition. — Springer Science & Business, 2008. — 420 p. Drawing on years of significant scientific advances and clinical developments, the editors of POMO III have thoroughly updated the highly praised first and second editions and added new chapters to reflect the knowledge emerging from research on genomics, proteomics, chemoprevention strategies, new molecular targets,...
ExLi4EvA, 2016. — 193 p. Written by an international team of experts in the field of human carcinogenesis, this book discusses recent advances in cancer research, which include the following topics: basic molecular and cellular mechanisms behind cancer growth, new approaches in cancer therapy, and cancer diagnostic. The book serves as a useful source of reference for cancer...
Humana Press Inc., 2007. — 483 p. — ISBN 978-0-89603-820-2. Cancer initiation and progression reflect the combined effects of tumor cellautonomous genetic alterations and the complex interplay of tumor cells with nontransformed host elements. Whereas intense effort has been directed towards elucidating the mechanisms by which mutations in oncogenes and tumor suppressors give...
Springer, 2011. - 484 p. This teaching monograph on systems approaches to cancer research and clinical applications provides a unique synthesis, by world-class scientists and doctors, of laboratory, computational, and clinical methods, thereby establishing the foundations for major advances not possible with current methods. Specifically, the book: Sets the stage by describing...
Academic Press, 2018. — 545 p. — (Translational Epigenetics). — ISBN: 978-0-12-811022-5. This book offers an in-depth exploration of noncoding RNAs and their role in epigenetic regulation of complex human disease, most notably cancer. In addition to examining microRNAs, this volume provides a unique evaluation of more recently profiled noncoding RNAs now implicated in...
Springer, 2009. — 396 p. The purpose of this book is to provide information on apoptotic processes involved in major neoplastic diseases and their translations into emerging anti-cancer strategies. The book is divided into 15 chapters, each of which will be focused on one particular cancer (breast, bladder, cervical, colorectal, esophageal, gastric, laryngeal, liver, lung,...
Springer Science Business Media Inc., 2005. — 213 p. — ISBN 978-0-387-25357-2 For my colleagues and I, this book is an experiment. Its ultimate success or failure is dependent upon the usefulness of the topics you, the reader, derive. We trust the reading of this monograph will be time well spent and I look forward to either hearing from you about what you liked or disliked or...
2 edition, Humana Press, 2017. — 873 p. — ISBN: 978-1-934115-18-3, 978-1-59745-458-2. Written by experts in the field Updated and revised to include current research Richly illustrated This book covers the concepts of molecular medicine and personalized medicine. Subsequent chapters cover the topics of genomics, transcriptomics, epigenomics, and proteomics, as the tools of...
Springer International Publishing, Switzerland, 2016. — 266 p. — (Recent Results in Cancer Research 207). — ISBN: 978-3-319-42116-2, 978-3-319-42118-6. The notion that tumor cells display characteristic alterations of metabolic pathways has significantly changed our understanding of cancer. While the first description of tumor-specific changes in cellular energetics was...
Springer, 2010. — 363 p. The pivotal role of mitochondrial functions in carcinogenesis is quite well established. However, the critical role of mitochondrial genome alterations to cancer development is muted in traditional textbooks. Recent scientific efforts have provided unequivocal evidence for mitochondrial genome mutations and content changes in cancer development,...
Nova Science, 2010. — 605 p. The presence of multiple cancers in one patient has excited the interest of many investigators, and considerable literature has accumulated on this subject. The scientific concepts and clinical importance of field cancerization are the subject matter of this book. This book is a compendium of importance to oncologists and cancer researchers and...
Springer Science & Business Media, 2008. — 798 p. DNA Tumor Viruses will focus on the DNA viruses in the human population that are associated with cancers. It will cover most of the viruses that are thought to contribute to human malignancy. This book will represent a comprehensive review of the field of DNA tumor virology. Right now, while there are books out there that cover...
Academic Press, 2019. — 676 p. — ISBN: 978-0-12-811785-9. This book offers a thorough survey of precision medicine and its diagnostic and therapeutic applications in oncology. Gathering contributions from leading international researchers in the field, chapters examine recent translational advances in oncogenomic methods and technologies, detail novel molecular classifications...
Elsevier, 2014. — 473 p. - Cancer Genomics addresses how recent technological advances in genomics are shaping how we diagnose and treat cancer. Built on the historical context of cancer genetics over the past 30 years, the book provides a snapshot of the current issues and state-of-the-art technologies used in cancer genomics. Subsequent chapters highlight how these approaches...
Springer-Verlag Italia, 2012. — 399 p. — ISBN: 978-88-470-2570-7 The future of oncology has a name: Molecular Medicine (MM). Molecular Medicine is a new science based on three pillars. Two of them are well known and evident in its very name: medical science and molecular biology. However, there is a general unawareness that MM is firmly based on a third but equally important...
London: Academic Press, 2015. — 418 p. — (Advances in Cancer Research Volume 126). — ISBN: 0128013818, 978-0-12-801381-6. Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics. Provides information on cancer research Outstanding...
Springer, 2020. — 332 p. This book aims to provide a guide for virologists, translational researchers, and clinicians in the field of cancer research by providing reference protocols and methodologies from vector development through clinical translation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their...
Academic Press, 2023. — 459 p. — ISBN: 978-0-12-824152-3. Oncogenic Viruses: Fundamentals of Oncoviruses provides an overview of the history of human oncoviruses, how to discover and define an oncovirus, how viruses cause cancer in general, their oncogenic mechanisms and epidemiology, and the cancer biology of oncoviruses. The book is organized into five main parts that include...
Academic Press, 2023. — 417 p. — ISBN: 978-0-12-824156-1. Oncogenic Viruses: Medical Applications of Viral Oncology Research, Volume Two builds on the introductory overview of Volume One, Oncogenic Viruses: Fundamentals of Oncogenic Viruses. It looks at recent advances and medical applications of research studies on oncoviruses, including examining oncoviruses on a molecular...
Springer, 2019. — 222 p. This textbook takes you on a journey to the basic concepts of cancer biology. It combines developmental, evolutionary and cell biology perspectives, to then wrap-up with an integrated clinical approach. The book starts with an introductory chapter, looking at cancer in a nut shell. The subsequent chapters are detailed and the idea of cancer as a mass of...
Springer, 2010. — 348 p. This book is comprised of four distinct sections: Epidemiology, Pathology, Molecular Genetics, and Inherited Susceptibility, with each section divided into chapters categorized by disease. Section A reviews the epidemiology of prostate and testicular cancer, with an emphasis on clinical and environmental factors associated with these diseases. Section B...
Humana Press, 2009. — 181 p. — ISBN: 978-1-60327-266-7. The chemokine receptors are a diverse family of seven-transmembrane G-protein-coupled receptors binding a large family of ligands. Chemokine receptors were first identified on leukocytes and mediate directed migration of many host cells to sites of ligand expression. It is now well established that most malignant cells...
Tokyo: Springer, 2016. — 218 p. — ISBN: 978-4-431-55937-5, 978-4-431-55939-9. Shows how sugar chains are critically involved in malignant phenotypes of cancers. Presents a variety of modes by which sugar chains modulate cell signals determining cell fates. Explains how up-to-date results of life technology and information are being applied in glycobiology research of cancers....
2nd edition. — Springer Science & Business Media, 2014. — 464 p. Tumor-Induced Immune Suppression - Prospects and Progress in Mechanisms and Therapeutic Reversal presents a comprehensive overview of large number of different mechanisms of immune dysfunction in cancer and therapeutic approaches to their correction. This includes the number of novel mechanisms that has never...
Cambridge University Press, 2014. — 956 p. — ISBN: 978-0-521-87662-9. The genomic era has allowed enormous strides in our understanding of the molecular changes that underlie malignant transformation. Mutations have been discovered that are critical drivers of large cross-sections of human cancers. These discoveries have allowed us to find drugs that target these drivers and...
Cham, Switzerland: Springer International Publishing, 2015. — 224 p. — (Recent Results in Cancer Research 200). — ISBN: 978-3-319-20290-7, 978-3-319-20291-4. Reviews up-to-date knowledge of chromosomal instability in cancer Examines strategies to harness this information for the better treatment of cancer patients This issue of Recent Results in Cancer Research presents a...
Springer International Publishing, Switzerlan, 2016. — 247 p. — (Advances in Experimental Medicine and Biology 930). — ISBN: 978-3-319-39404-6, 978-3-319-39406-0. This book discusses properties of apoptosis and other cell death modalities in cancer pathogenesis and treatment. Its nine chapters discuss modulation of anti-tumor inflammatory and immune responses, effects on the...
Springer, 1996. — 301 p. In metastasis, tumor cells disseminate from the primary lesion and home to secondary organs where they may remain dormant for a long time. Metastasis formation is still the most feared manifestation for tumor patients and clinicians. Although improvements have been made concerning earlier detection and specific therapy, most of the cancer patients still...
Springer, 1996. — 296 p. In metastasis, tumor cells disseminate from the primary lesion and home to secondary organs where they may remain dormant for a long time. Metastasis formation is still the most feared manifestation for tumor patients and clinicians. Although improvements have been made concerning earlier detection and specific therapy, most of the cancer patients still...
Springer, 1996. — 273 p. In metastasis, tumor cells disseminate from the primary lesion and home to secondary organs where they may remain dormant for a long time. Metastasis formation is still the most feared manifestation for tumor patients and clinicians. Although improvements have been made concerning earlier detection and specific therapy, most of the cancer patients still...
Taylor & Francis Group, 2014. - 501 p. - Cancer-causing viruses, also called oncoviruses, play a key role in the development of certain cancers. They contribute to genetic changes that disrupt the cell cycle machinery, interfering with functions such as cell growth. Cancer-Causing Viruses and Their Inhibitors presents a plethora of research from internationally reputed...
London: Academic Press, 2015. — 473 p. — (Advances in Pharmacology 74). — ISBN: 0128031190, 9780128031193. Cytochrome P450 Function and Pharmacological Roles in Inflammation and Cancer, the latest volume in the Advances in Pharmacology series, presents not only the function of cytochrome P450 but also its pharmacological roles in inflammation and cancer. Contains contributions...
Wiley Blackwell, 2013. — 228 p. A focused, accessible introduction to this key aspect of cancer biology. It covers the individual cell signalling pathways that are known to be involved in cancer development, and, most important, includes the cross– interactions between the pathways together with the current therapeutic approaches. This is a ‘must–have’ for advanced...
Academic Press, 1994. — 490 p. — ISBN: 0-12-333530-2 Human tumor cells in culture are valuable for studying cancer causes and properties. This convenient reference provides useful information for cancer researchers on commonly used, established tumor cell lines of the major human organ systems.Atlas of Human Tumor Cell Lines includes data about morphological, metabolic,...
Springer International Publishing AG, 2017. — 302 p. — ISBN: 978-3-319-53657-6. Divided into two volumes the work offers a so far unmatched broad and at the same time deep knowledge on molecular and cellular mechanisms of carcinogenesis and offers comprehensive insight into clinical, therapeutic and technological aspects. This 1st Volume presents tumor entities of the ocular...
Springer International Publishing AG, 2017. — 373 p. — ISBN: 3319536605. Together with Volume 1, this book provides an inclusive overview of the molecular and cellular mechanisms of carcinogenesis and offers comprehensive insights into related clinical and therapeutic aspects. This second volume complements the first by presenting and concisely explaining the carcinogenesis of...
4 edition, Chichester, UK: Wiley-Blackwell, 2015. — 648 p. — ISBN: 978-1-118-79553-8, 9781118795514. The first three editions of this acclaimed book presented a much-needed conceptual synthesis of this rapidly moving field. Now, Cancer Cytogenetics, Fourth Edition, offers a comprehensive, expanded, and up-to-date review of recent dramatic advances in this area, incorporating a...
Bookboon, 2009. — 46 p. Introduction to Cancer Biology is a short primer on how cancers develop and grow. The aim of this book is to provide a gentle exploration of the fundamental concepts in a easy-to-understand format, using examples and key figures for illustration. It is written in a style to help the reader understand the six basic principles that inform our current...
New York University Press, 1997. — 242 p. Growing numbers of cancer patients are exploring diet, food supplements, herbs, and nontoxic immunotherapies like bacterial vaccines as a means of therapy. Yet most cancer research organizations refuse to even evaluate these alternatives. Can Bacteria Cause Cancer? argues convincingly that unless this neglected world of alternative...
Wiley, 2014. — 409 p. — ISBN: 978-1-118-82655-3. A new perspective on the link between inflammation and cancer Inflammation is the human body's normal biological response to threats in the modern world, as well as a defense against the harmful influence of pathogens, the environment, and poor nutrition. But what happens when the inflammatory response is triggered repeatedly and...
Wiley, 2010. With a weight-of-the-evidence approach, cancer risk assessment indentifies hazards, determines dose-response relationships, and assesses exposure to characterize the true risk. This book focuses on the quantitative methods for conducting chemical cancer risk assessments for solvents, metals, mixtures, and nanoparticles. It links these to the basic toxicology and...
Springer, 2017. — 230 p. — ISBN: 978-3-319-61803-6. In this special volume of Current Topics in Microbiology and Immunology (CTMI), the scientific chapters are focused on current research developments in the fields to which Peter Vogt made preeminent contributions: viruses, genes, and cancer. Several chapters specifically highlight virus-host interactions, the role of infectious...
Academic Press, 2016. — 288 p. — (Advances in Cancer Research Volume 129). — ISBN: 0128022906, 978-0-12-802290-0, 9780128024836, 0128024836. Focuses on the multifunctional molecular chaperone Hsp90 which regulates the post-translational stability and function of a broad repertoire of client proteins Highlights the rapidly evolving understanding of the fundamental roles of Hsp90...
University of California Press, 2013. — 304 p. — ISBN: 0520276566, 0520276574. Nearly half of all Americans will be diagnosed with an invasive cancer — an all-too ordinary aspect of daily life. Through a powerful combination of cultural analysis and memoir, this stunningly original book explores why cancer remains so confounding, despite the billions of dollars spent in the...
Intech, 2012. — 257 p. Esophageal Cancer illustrates recent achievements and investigations in the esophageal tumorigenesis from different perspectives. Readers find mechanisms involved in esophageal tumorigenesis, cellular, molecular, genetic, epigenetics, and proteomics, their relevance as the novel biomarkers and application in esophageal cancer diagnosis and therapy. The...
Springer, 2018. — 328 p. — ISBN: 1493975676. This volume provides a broad spectrum of research models, techniques, and protocols. Chapters are divided into sections providing detailed information on the background and context for the chosen topic of interest, a list of the necessary materials and reagents needed for each topic, as well as the step-by-step laboratory protocols...
Springer Science & Business Media, 2012. — 408 p. A key goal in the treatment of cancer is to achieve selective and efficient killing of tumor cells. The aim of Cell Death Signaling in Cancer Biology and Treatment is to describe state-of-the-art approaches and future opportunities for achieving this goal by targeting mechanisms and pathways that regulate cancer cell death. In...
Dordrecht: Springer Netherlands, 2015. — 366 p. — ISBN: 978-94-017-7379-9, 978-94-017-7380-5. Contributions from leading scientists in the field will ensure access to the most reliable and up to date research and concepts (Novelty and reliability) Basic and translational aspects will attract basic scientists and clinicians alike Comprehensive color illustrations which will be...
Academic Press, 2018. — 109 p. — ISBN: 978-0-12-813673-7. This book starts with a basic question, why do we sometimes observe accelerated metastatic growth after resection of primary tumors? Next, it helps readers understand the systemic nature of cancer and how it affects treatment approaches and decisions. The book puts together aspects of cancer that many readers have most...
New York: Humana Press, 2017. — 248 p. — (Methods in Molecular Biology 1513). — ISBN: 978-1-4939-6539-7, 978-1-4939-6537-3. This volume is a valuable and timely resource for a broad audience with interests in basic and translational cancer biology, cancer drug development, as well as in the practice of personalized oncology. Written in the highly successful Methods in Molecular...
Humana Press, 2008. — 719 p. — ISBN: 978-1-58829-577-4. The structure of Molecular Targeting in Oncology is designed to cover the flavor of the rapidly developing area of targeted therapies for the treatment of patients with cancer. Targeted therapies will likely continue as focus for future drug development as the molecular pathways mediating tumor initiation, progression, and...
Bentham eBooks, 2016. — 157 p. — ISBN: 978-1-68108-347-6. A malignant tumor is an actively growing tissue, composed of cells derived from a single cell line that has undergone irreversible differentiation. These cells are invasive and also metastasize in the body, resulting in malignant cancer. Recent research suggests that a malignant tumor originates from cancer stem cells...
Chelsea House Publishers, 2007. — 136 p. In a clear and accessible manner, Stages of Cancer Development follows the evolution of cancer from a single genetically altered cell, through the stages of hyperplasia, dysplasia, carcinoma in situ, to full-blown cancer. This book explores the evolution of cancer from a single genetically altered cell through all stages od development...
Springer Science & Business Media, 2007. — 157 p. Convertases are widely expressed activating enzymes involved in various physiological and pathological processes. The purpose of this book is to provide detailed and updated information on the role of these molecules in cancer. This book is the first to summarize current knowledge about the importance of protein precursors...
4th Edition. - Oxford University Press, 2005. - 556 p. This new edition o Introduction and Molecular Biology of Cancer provides a concise yet comprehensive overview of cancer biology, covering the current status of both research and treatment. For the student or new researcher the breadth of cancer research can appear daunting, yet a broad understanding is essential for...
Springer, 2014. — 293 p. The collection of chapters in this proceeding volume reflects the latest research presented at the Aegean meeting on Tumor Microenvironment and Cellular Stress held in Crete in Fall of 2012. The book provides critical insight to how the tumor microenvironment affects tumor metabolism, cell stemness, cell viability, genomic instability and more....
Dordrecht, Netherlands: Springer, 2015. — 271 p. — ISBN: 978-94-017-9731-3, 978-94-017-9732-0. Covers the entire, interdisciplinary field of kinesins and cancer through expert contributions Offers a timely reference standard on the relevance of kinesins to cancer treatment Contributes to potential initial validation of mitotic kinesins as targets for drug development in cancer...
Nova Science Publishers, 2013. — 194 p. In this book, the authors study the mutual interaction of cancer and its host body. The authors present the point of view that this interaction is mediated by human consciousness. Although the term cancer refers to undisciplined and uncontrollable cellular growth, a basal cell carcinoma of the skin is quite different from adenocarcinoma...
New York: Humana Press, 2014. — 439 p. — (Cancer Drug Discovery and Development). — ISBN: 978-1-4614-8038-9, 978-1-4614-8039-6. At the moment, there is no dedicated book to summarize the roles, the significance, and potential therapeutic targeting of transcriptional factors from the perspective of signaling cascade, and thus, directly impacting the functionality of...
Cambridge University Press, 2017. — 183 p. — ISBN10: 1107109590. Recent years have witnessed an increasing number of theoretical and experimental contributions to cancer research from different fields of physics, from biomechanics and soft-condensed matter physics to the statistical mechanics of complex systems. Reviewing these contributions and providing a sophisticated...
Nova Science Publishers, 2013. — 189 p. Cancer is characterised by uncontrolled cell division and the potential of the cells to invade surrounding tissues and spread around the body. Most of these changes in cellular behaviour are the result of alterations in the function or levels of the proteins that control these processes. And these alterations are, in turn, usually caused...
Springer International Publishing, 2016. — 552 p. — (Advances in Experimental Medicine and Biology 916). — ISBN: 978-3-319-30652-0, 978-3-319-30654-4. Provides the most up-to-date research on zebrafish models for oncogene and tumor suppressor discovery Explores potential drug targets in various cancers, including leukemia, melanoma, pancreatic and liver cancers Reviews...
Harvard University Press, 2017. — 265 p. — ISBN10: 0674088743. — ISBN13: 978-0674088740. An innovative theory proposes a new therapeutic strategy to break the stalemate in the war on cancer. It is called cancer stem cell (CSC) theory, and Lucie Laplane offers a comprehensive analysis, based on an original interdisciplinary approach that combines biology, biomedical history, and...
Cham, Switzerland: Springer International Publishing, 2015. — 144 p. — ISBN: 978-3-319-22188-5, 978-3-319-22189-2. Presents the latest developments in personalized medicine clinical trials in oncology Describes the design and implementation of the SHIVA trial launched by the Curie Institute, France Shows the latest statistical models for high-throughput molecular techniques,...
The National Academies Press, 2013. — 323 p. In the United States, approximately 14 million people have had cancer and more than 1.6 million new cases are diagnosed each year. However, more than a decade after the Institute of Medicine (IOM) first studied the quality of cancer care, the barriers to achieving excellent care for all cancer patients remain daunting. Care often is...
London: Academic Press, 2016. — 511 p. — ISBN: 0128038926, 978-0-12-803892-5, 9780128039342, 0128039345. This book introduces the basic concepts and advanced understanding of cancer stem cells, covering general overviews, organ-specific identifications, and their characteristic mechanisms. The book also explores innovative therapeutic strategies in preclinical and clinical...
Springer, 2017. — xiv, 670 p. This book integrates the disciplines of cancer pathology and epidemiology to provide a synergistic and complementary approach to understanding the molecular mechanisms of cancer. This book provides relevant information on the diagnostic, prognostic and predictive molecular pathology of cancer. Epidemiological studies, including descriptive...
Taylor & Francis Group, 2013. - 426 p. - MicroRNA (miRNA) biology is a cutting-edge topic in basic as well as biomedical research. This is a specialized book focusing on the current understanding of the role of miRNAs in the development, progression, invasion, and metastasis of diverse types of cancer. It also reviews their potential for applications in cancer diagnosis,...
CRC Press, 2018. — 382 p. — ISBN10: 1315894696, 13 978-1315894690. This is the first-and only-publication available which provides the most recent information in this particular field of biomedicine. Interleukin-2 (IL-2) and IL-2 activated killer cells have been shown to have a potential in the treatment of a variety of human malignant diseases. This work comprehensively...
Springer Science & Business Media, 2006. — 254 p. In this book, tumour growth is perceived as a deviation from the normal development of the human organism. The molecular, cellular, and tissue determinants of different tumours are discussed showing that each is a different disease, often corresponding to a particular developmental stage. The natural history of several cancers...
Taylor & Francis Group, 2013. - 714 p. - DNA repair is a rapidly advancing field in biology and these systems represent a major defense mechanism against environmental and intracellular damaging agents such as sunlight, ionizing radiation, and reactive oxygen species. With contributions from eminent researchers, this book explores the basics and current trends in this critical...
Springer Netherlands, 2013. — 210 p. Metastatic dissemination of cancer is a main cause of cancer related deaths, therefore biological mechanisms implicated in metastatic process presents an essential object of cancer research. This research requires creation and utilization of adequate laboratory models. The book describes main approaches to model processes of metastatic...
Springer International Publishing, 2015. — 247 p. — (Cancer Metastasis - Biology and Treatment 20). — ISBN: 978-3-319-12135-2, 978-3-319-12136-9. Connects cancer metastasis with genomic instability in a comprehensive manner Outlines the fundamental mechanisms responsible for these cellular and tissue phenotypes Reviews emerging themes and highlights new therapeutic approaches...
Chelsea House Publishers, 2008. — 145 p. The books in The Biology of Cancer series reveal information about the causes of the disease; the DNA changes that result in tumor formation; ways to prevent, detect, and treat cancer; and detailed accounts of specific types of cancers that occur in particular tissues or organs. Books in this series describe what happens to cells as they...
Dordrecht, Netherlands: Springer, 2015. — 539 p. — ISBN: 978-94-017-9638-5, 978-94-017-9639-2. Presents original research data in figures that illustrate new insights in cancer epigenetics Collates fundamentals of epigenetics, the latest research and therapeutic design in treatment of cancer Explores links between cancer research, medicine, and anthropology This book explores...
Humana Press, 2014. — 362 p. The imbalance between rapidly proliferating tumor cells and inadequate and inefficient tumor vasculature leads to a decrease in oxygen levels (hypoxia and/or anoxia) in tumor tissues. Intra-tumor hypoxia profoundly affects the biological behavior of cancer cells, which become resistant to conventional therapies and acquire a more invasive and...
4th Edition. - Elsevier, 2015. - 1019 p. - The Molecular Basis of Cancer arms you with the latest knowledge and cutting-edge advances in the battle against cancer. This thoroughly revised, comprehensive oncology reference explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of this disease. A team of leading...
Second Edition. — IOP Concise Physics, 2018 — 489 p. — ISBN: 0750321148. To increase the healing opportunities of cancer, it is important to impair the dissemination and the spreading of cancer cells from the initial tumor and the formation of metastases in other organs or tissues of the human body. The underlying physical principles of these oncological processes are a major...
Second Edition. — IOP Concise Physics, 2018. — 543 p. — ISBN: 0750317515. This revised second edition is improved linguistically with multiple increases in the number of figures and the inclusion of several novel chapters such as actin filaments during matrix invasion, microtubuli during migration and matrix invasion, nuclear deformability during migration and matrix invasion,...
Springer International Publishing, 2016. — 246 p. — ISBN: 978-3-319-24949-0, 978-3-319-24951-3. This volume explores the epigenetic alterations and their association with various human cancers. Considering one of human cancer as an example, individual chapters are focused on defining the role of epigenetic regulators and underlying mechanisms in cancer growth and progression....
Springer International Publishing, 2016. — 56 p. — ISBN: 978-3-319-25599-6, 978-3-319-25601-6. This exciting SpringerBrief presents evidence for new ideas that will challenge several theories of how cancer biology is understood. Cancer biology has undergone several intellectual revolutions in the past 50 years. A mutation-centric view of cancer has given way to the tumor...
Springer, 2017. — 453 p. — ISBN: 978-3-662-53773-2. Germ Cell Tumors: Classifications, Definitions, and Terminology. The Epidemiology of Malignant Germ Cell Tumors: The EUROCARE Study. Germ Cell Tumors from a Developmental Perspective: Cells of Origin, Pathogenesis, and Molecular Biology (Emerging Patterns). Diagnostic Immunopathology of Germ Cell Tumors. Management of Germ...
Infobase Publishing, 2005. — 162 p. The ''New Biology'' series. Cancer presents the past, present, and future of cancer research in a readable and comprehensive format. It begins with a short summary of cell biology and continues with an overview of the way cancer cells work and how researchers have discovered the nature of these cells. The book looks closely at the successes...
Cham, Switzerland: Springer International Publishing, 2015. — 144 p. — ISBN: 978-3-319-25668-9, 978-3-319-25670-2. This book explores the role of cancer stem cells in the diagnosis, treatment, and cure of cancers. This book also tackles novel methodology for cancer stem cell marker identification, cancer stem cell respiration and metabolism, genetic and epigenetic mechanisms...
3rd Edition. - Oxford University Press, 2012. - 365 p. - Cells in our body undergo tightly regulated replication to enable growth to occur in a precise, and to ensure that damaged or worn out tissues are replaced. Regulation is mediated via many different mechanisms; it is when these mechanisms fail, and regulation is lost, that cancer can result. Recent advances in molecular...
2nd Edition. — Wiley, 2013. — 634 p. This capturing, comprehensive text, extensively revised and updated for its second edition, provides a detailed overview of the molecular mechanisms underpinning the development of cancer and its treatment. Bench to Bedside : A key strength of this book that sets it apart from general cancer biology references is the interweaving of all...
Chichester, UK: Wiley-Blackwell, 2015. — 376 p. — ISBN: 978-1-118-67062-0, 169-193-213-2, 9781118670583. The field of cancer stem cells is expanding rapidly, with many groups focusing on isolating and identifying cancer stem cell populations. Although some progress has been made developing efficient cancer therapies, targeting cancer stem cells remains one of the important...
Springer International Publishing, 2017. — 302 p. — (Energy Balance and Cancer 12). — ISBN: 978-3-319-41675-5, 978-3-319-41677-9. Analyzes the components and molecular biology of adipose tissue and differences in activities and interactions related to its body distributionExplores both the physiologic and pathologic functions of the major adipocytokines, including their...
Cham, Switzerland: Springer International Publishing, 2015. — 328 p. — ISBN: 978-3-319-14339-2, 978-3-319-14340-8 This book provides a simplified, yet comprehensive, overview of the signalling pathways operating between and inside cells, which will help younger oncologists find their way in the labyrinth of signalling pathways and in the multitude of signals and signal...
Springer Science+Business Media, LLC 2012. - 868 p. ISBN: 144199999X. The acknowledgment that viruses are potent biological factors in driving many cancers have seen a dramatic upsurge in recent years in large part to the success of the human papilloma virus vaccine against invasive cervical carcinomas and followed by the awarding of the noble prize in medicine in 2008 to Dr....
Cham, Switzerland: Springer International Publishing, 2015. — 490 p. — ISBN: 978-3-319-19982-5, 978-3-319-19983-2. This volume collates world experts’ insights into the molecular biology of cancer chromosomes, their abnormalities and the subsequent cellular consequences. Exploring themes involving oncogenes, such as by chromosomal translocations, other genome rearrangements and...
Cham, Switzerland: Springer International Publishing, 2015. — 210 p. — (Topics in Medicinal Chemistry 16). — ISBN: 978-3-319-19754-8, 978-3-319-19755-5. Overview chapters introduce the newcomer to the topic covered Series covers hot topics of frontier research summarized by reputed scientists in the field Volumes are useful and of relevance for a long period of time Medicinal...
Academic Press, 2018. — 379 p. — (Translational Epigenetics). — ISBN: 978-0-12-809552-2. This book provides a comprehensive analysis of epigenetic signatures that govern disease development, progression and metastasis. Epigenetic signatures dictating tumor etiologies present an opportunity for biomarker identification which has broad potential for improving diagnosis,...
Wiley, 2012. — 459 p. The book addresses controversies related to the origins of cancer and provides solutions to cancer management and prevention. It expands upon Otto Warburg's well-known theory that all cancer is a disease of energy metabolism. However, Warburg did not link his theory to the "hallmarks of cancer" and thus his theory was discredited. This book aims to provide...
Tokyo: Springer, 2015. — 268 p. — ISBN: 4431553266, 9784431553267. Facilitates a scientific understanding of up-to-date knowledge on cancer in immunotherapy Includes information on recent Japanese studies of inflammation, immunity, and cancer Is written by scientists directly involved in the field This book overviews cancer immunity from broad scientific fields, based on the...
Academic Press, 2017. — 336 p. — ISBN: 978-0-12-812896-1. This book discusses molecular mechanisms of cancer initiation, growth and secondary spread, emphasizing how this information can be used to devise new modes of treatment of cancer, especially in combatting secondary spread. The book addresses the basic concepts relating to cancer biology, the genetic determinants, and...
Springer, 2013. — 745 p. — ISBN: 978-94-007-6216-9 Analysis of multidirectional immunological responses at the tumor site allows forming a new concept of The Tumor Immunoenvironment, which is introduced and discussed in the present book with a particular focus on the role of immune cells in controlling the tumor microenvironment at different stages of cancer development. The...
Springer, 2013. — 2276 p. — ISBN: 978-94-007-6217-6 Analysis of multidirectional immunological responses at the tumor site allows forming a new concept of The Tumor Immunoenvironment, which is introduced and discussed in the present book with a particular focus on the role of immune cells in controlling the tumor microenvironment at different stages of cancer development. The...
Springer Singapore, 2016. — 458 p. — (Advances in Experimental Medicine and Biology 927). — ISBN: 978-981-10-1496-3, 978-981-10-1498-7. Provides a comprehensive knowledge of long and short ncRNAs. Chapters highlight recent advances in specific topics, like the molecular mechanisms of various classes of ncRNAs in cancer. Contributed by experts in this field. The book conveys a...
Humana Press, 2011. — 462 p. During the last 30 years it has become clearly evident that oxidative stress and free radical biology play key roles in carcinogenesis, cancer progression, cancer therapy, and normal tissue damage that limits treatment efficacy during cancer therapy. These mechanistic observations have led to the realization that free radical biology and cancer...
Springer, 2009. — 254 p. The book introduces the new field of lymphatic vessel growth and development, and its relationship to the metastatic spread of cancer cells. The book covers all aspects of this new field from the fundamental role that protein growth factors and their receptors play in lymphangiogenesis to the potential application of these advances to cancer diagnosis...
Humana Press, 2017. — 197 p. — (Methods in Pharmacology and Toxicology). — ISBN: 978-1-4939-6741-4, 978-1-4939-6743-8. Explores epigenetics from the wide-angle view of epigenomics Features detailed methods sections which include data analyses, troubleshooting, and feasibility in different experimental settings Includes contributions from key researchers in the field This...
Humana Press, 2011. — 708 p. Beverly A. Teicher and a panel of leading experts comprehensively describe the state-of-the-art in animal tumor model research. This volume updates and extends the comprehensive presentations in the first edition. The wide array of models detailed form the basis for the selection of compounds and treatments that go into clinical testing of patients,...
Cambridge University Press, 2015. — 531 p. — ISBN: 0521493390, 978-0-521-49339-0, 9780511979811. The heterogeneity in alterations and the failure to detect consistent changes in a unique set of gene(s) or gene products in similar and histologically well defined neoplasms pose a challenge for the accurate diagnosis, prognosis and therapy of cancer. Consequently, there is a need...
Springer International Publishing, 2015. — 436 p. — (Advances in Experimental Medicine and Biology 815). — ISBN: 978-3-319-09613-1, 978-3-319-09614-8. Explores effects of alcohol on cancer stem cells, metabolomics, biomarkers, and more Challenges and updates the epidemiology of alcohol and cancer Discusses how alcohol affects tissue-specific cancers In the recent years, a...
Humana Press, 2015. — 804 p. — ISBN: 1493918036, 9781493918034. Includes cutting-edge techniques in cancer epigenetic research Provides step-by-step detail essential for reproducible results Contains key notes and implementation advice from the experts This volume shares technologies that detect common epigenetic changes which are very important in the early detection,...
Wiley, 2017. — 357 p. Cancer, which has become the second-most prevalent health issue globally, is essentially a malfunction of cell signaling. Understanding how the intricate signaling networks of cells and tissues allow cancer to thrive - and how they can be turned into potent weapons against it - is the key to managing cancer in the clinic and improving the outcome of cancer...
The Experiment, 2013. — 344 p. — ISBN10: 1615191976, ISBN13: 978-1615191970. One of Publishers Weekly’s Top Ten Spring 2013 Science Books Philadelphia, 1959: A scientist scrutinizing a single human cell under a microscope detects a missing piece of DNA. That scientist, David Hungerford, had no way of knowing that he had stumbled upon the starting point of modern cancer...
The Experiment, 2013. — 344 p. — ISBN10: 1615191976, ISBN13: 978-1615191970. One of Publishers Weekly’s Top Ten Spring 2013 Science Books Philadelphia, 1959: A scientist scrutinizing a single human cell under a microscope detects a missing piece of DNA. That scientist, David Hungerford, had no way of knowing that he had stumbled upon the starting point of modern cancer...
CRC Press, 2006. — 596 p. Molecular Carcinogenesis and the Molecular Biology of Human Cancer provides a technical, as well as historical, overview of research covering the science of cancer. This volume explores molecular information specific to chemical, viral, and radiation carcinogenesis, explains the working of cellular oncogenes and tumor suppressor genes, and also...
Springer, 2007. — 644 p. Cancer may constitute the most extensively studied functions constitute a second line of defense that disease entity of our time. Nevertheless, our com- protects against transforming defects in oncogenes prehension of the cellular and molecular pathology or tumor-suppressor genes and are here considered of malignant transformation is incomplete. In view...
Birkhauser Verlag, 2006. — 133 p. Introduction to TNF/pathophysiology of TNF History of development of TNF inhibitors Pharmacology of TNF inhibitors Etanercept in rheumatology Etanercept in dermatology and off-label use Infliximab in rheumatology Infliximab in dermatology, gastroenterology, and off-label use Adalimumab in rheumatology Adalimumab in dermatology A review of the...
2nd edition - Garland Science, 2014 - 962 p. - ISBN: 978-0-8153-4219-9. The Biology and Genetics of Cells and Organisms. The Nature of Cancer. Tumor Viruses. Cellular Oncogenes. Growth Factors, Receptors, and Cancer. Cytoplasmic Signaling Circuitry Programs Many of the Traits of Cancer. Tumor Suppressor Genes. pRb and Control of the Cell Cycle Clock. p53 and Apoptosis: Master...
Cambridge: Academic Press, 2016. — 376 p. — (Advances in Cancer Research 132). — ISBN: 0128041404, 978-0-12-804140-6. Presents groundbreaking information on the molecular and cellular basis of metastasis. Provides information on cancer research. Outstanding and original reviews. Suitable for both researchers and students. Molecular and Cellular Basis of Metastasis: Road to...
Springer, 2007. — 275 p. — ISBN: 978-3-540-70852-0. The concept that cancer stem cells play an important role in malignant tumors is gaining more and more support due to recent advances in the field. The latest progress in this area is increasingly reported and commented on in the lay press, documenting the high excitement and hopes it generates. An intricate relationship...
Singapore: World Scientific Publishing Company, 2014. - 532 p. The book aims to provide an introduction to mathematical models that describe the dynamics of tumor growth and the evolution of tumor cells. It can be used as a textbook for advanced undergraduate or graduate courses, and also serves as a reference book for researchers. The book has a strong evolutionary component...
Springer, 2015. — 446 p. — ISBN: 978-94-017-9420-6, 978-94-017-9421-3. It is now established that dysregulated cell stress response pathways play a critical role in tumorigenesis, and a refined mechanistic understanding of this phenomenon at the molecular level promises to open new avenues for targeted therapeutic strategies that may benefit cancer patients in the near future....
Springer, 2010. — 293 p. The poor prognosis and high mortality for cancer patients are majorly ascribed to tumor metastasis, one of the most complicated pathological processes. Elucidation of molecular mechanisms for metastasis is essential for management and prevention of this lethal condition. In the book to be published, we take comprehensive review in regard with the signal...
Springer Nature, Singapore, Pte Ltd., 2017. — 106 p. – ISBN: 981104970X. This book covers the broad area related to Notch-mediated regulation of the immune system and tumorigenesis. Notch signaling was originally identified as a crucial pathway to regulate cell fate choice. Subsequent studies, however, have revealed that Notch regulates many steps of immune cell differentiation...
Academic Press, 2014. - 351 p. Interleukins in Cancer Biology responds to the growing need for credible and up-to-date information about the impact of interleukins on occurrence, development and progression of cancer. It provides reliable information about all known interleukins (38), describes recent discoveries in the field, and moreover, suggests further directions of...
Springer, 2011. — 254 p. The World Health Organization has identified chronic alcohol consumption as one of the top ten risk factors for worldwide burden of disease. The International Agency for Research on Cancer has identified alcohol as carcinogenic to humans, including cancers of the upper aerodigestive tract, colon, liver and breast. Alcohol’s actions may be direct e.g....
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