InTech, 2012. - 214 p. - This book contains review articles dealing with protein interactions with the above mentioned factors. The enclosed articles could be informative and stimulating for readers interested in protein binding partners and the consequences of such interactions. Transferrin Binding Proteins as a Means to Obtain Iron in Parasitic Protozoa The Potential Role of...
ITexLi, 2016. – 443 p. – ISBN: 953512272X This book RNA interference provides an updated knowledge and progress on RNAi in various organisms, explaining basic principles, types, and property of inducers, structural modifications, delivery systems/methodologies, and various successful bench-to-field or clinic applications and disease therapies with some aspects of limitations,...
Academic Press, 2019. — 282 p. — (Perspectives in Translational Cell Biology). — ISBN: 978-0-12-813832-8 This book links laboratory and clinical data within primary and secondary care to clinical research data and offers a holistic and innovative approach to chronic inflammation and ageing. Understanding the role of inflammation as a part of clinical disease states is becoming...
Royal Society of Chemistry, 2011. — 303 p. — ISBN: 978-1-84973-160-7 Intracellular cell signaling is a well understood process. However, extracellular signals such as hormones, adipokines, cytokines and neurotransmitters are just as important but have been largely ignored in other works. They are causative agents for diseases including hypertension, diabetes, heart disease, and...
Marcel Dekker, 2003. — 304 p. ISBN10: 0824743121 From disease marker identification to accelerated drug development, Protein Arrays, Biochips, and Proteomics offers a detailed overview of current and emerging trends in the field of array-based proteomics. This reference focuses on innovations in protein microarrays and biochips, mass spectrometry, high-throughput protein...
Taylor & Francis, 2007. - 1725 p. Professors, lecturers, and instructors will find the fifth edition of the book Molecular Biology of the Cell and its accompanying Problems Book to be an excellent choice for guiding their students through the maze of the cell's molecular structures and biochemical processes.With countless colorful illustrations and a large number of photographs...
6th edition. — Garland Science, 2015. — 1465 p. Authors: Alberts B., Johnson A., Lewis J., Morgan D., Raff M., Roberts K., Walter P. As the amount of information in biology expands dramatically, it becomes increasingly important for textbooks to distill the vast amount of scientific knowledge into concise principles and enduring concepts.As with previous editions, Molecular...
6th edition. — Garland Science, 2015. — 1465 p. Authors: Alberts B., Johnson A., Lewis J., Morgan D., Raff M., Roberts K., Walter P. As the amount of information in biology expands dramatically, it becomes increasingly important for textbooks to distill the vast amount of scientific knowledge into concise principles and enduring concepts.As with previous editions, Molecular...
By Bruce Alberts, Rebecca Heald, Alexander Johnson, David Morgan, Martin Raff, Keith Roberts, Peter Walter, the Estate of Julian Lewis, John Wilson, and Tim Hunt. — 7th edition. — W.W. Norton & Co, 2022. — 1552 p. What’s New in the Seventh Edition? Every chapter in the Seventh Edition has been significantly updated with information on discoveries in the field of cell biology....
Wiley-Blackwell, 2007. - 748 p. ISBN: 1405103795 More accessible to beginning students in the field than its encyclopedic counterparts, Fundamental Molecular Biology provides a distillation of the essential concepts of molecular biology, and is supported by current examples, experimental evidence, an outstanding art program, multimedia support and a solid pedagogical framework....
2nd edition. — Wiley, 2012. — 687 p. — ISBN: 978-1-118-05981-4 Perfect for a single term on Molecular Biology and more accessible to beginning students in the field than its encyclopedic counterparts, Fundamental Molecular Biology provides a distillation of the essential concepts of molecular biology, and is supported by current examples, experimental evidence, an outstanding...
2nd Edition. — John Wiley & Sons, Inc., Canada, 2014. — 346 p. — ISBN: 978-1-118-35633-3. In August 1999, at the Joint Statistical Meetings in Baltimore, two of us [DA & JC] were invited to present a paper on “The Analysis of DNA Microchip Data.” This was the first presentation in any Joint Statistical Meetings on the topic of DNA microarrays, as they are now called. In just a...
Humana Press, 2018. — 351 p. — (Methods in molecular biology). — ISBN: 1493978187, 9781493978182, 1493978195, 9781493978199. This detailed book aims to address the need for standardizing key steps in plant metabolomics research that is still considered a critical issue in the field. The collection unites diverse mass spectrometry (MS)-based protocols, from sample preparation...
Cambridge University Press, 2018. — 535 p. — ISBN: 978-1-107-17037-7. Recent advances in genome editing tools using endonucleases such as TALENs, ZFNs, and CRISPRs, combined with genomic engineering technologies, have opened up a wide range of opportunities from applications in the basic sciences and disease biology research, to the potential for clinical applications and the...
Springer, 2013. — 365 p. This Springer Protocols manual is a practical guide to the application of key molecular biology techniques in microbiological research. The focus is on experimental protocols, which are presented in an easy-to-follow way, as step-by-step procedures for direct use in the laboratory. Notes on how to successfully apply the procedures are included, as well...
Cold Spring Harbor Laboratory Press, 2012. — 345 p. Once thought to be just a messenger that allows genetic information encoded in DNA to direct the formation of proteins, RNA (ribonucleic acid) is now known to be a highly versatile molecule that has multiple roles in cells. It can function as an enzyme, scaffold various subcellular structures, and regulate gene expression...
John Wiley & Sons, 2003. — 4648 p. Escherichia coli, Plasmids, and Bacteriophages Preparation and Analysis of DNA Enzymatic Manipulation of DNA and RNA Preparation and Analysis of RNA Construction of Recombinant DNA Libraries Screening of Recombinant DNA Libraries DNA Sequencing Mutagenesis of Cloned DNA Introduction of DNA into Mammalian Cells Analysis of Proteins Immunology...
Humana Press, 2001. - 261 p. - Internationally recognized investigators review the latest developments in, and novel approaches to, understanding the prion protein and prion diseases at the molecular level. Utilizing a variety of cutting-edge techniques, these distinguished scientists seek to define the normal function of a prion protein, to detect and measure the early immune...
CRC Press, Taylor & Francis Group, 2010, 492 p. Assembling the work of an international panel of researchers, Mass Spectrometry of Nucleosides and Nucleic Acids summarizes and reviews the latest developments in the field and provides a window on the next generation of analysis. Beginning with an overview of recent developments, the book highlights the most popular ionization...
Springer, 2013. - 300 p. - CRISPR/Cas is a recently described defense system that protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR/Cas systems has been identified in at least half of the available prokaryotic genomes. On-going structural and functional analyses have resulted in a far...
World Scientific Publishing, 2017. — 180 p. — ISBN: 9813223707, 978-9813223707 Actions of living beings at any stage of life are of general interest; molecular machines can be a replica of such activities. Stimuli guided movements and shape changes of molecules are one of the rapidly developing areas on which fundamental principles of molecular machine banks. Thus, the...
Springer-Verlag, 2007. — 375 p. The central goal of the present tutorial book is to stimulate this integration by bringing these different disciplines together. The idea of such a book emerged during the interdisciplinary workshop Structural approaches to sequence evolution: Molecules, networks, populations that we organized at the Max-Planck-Institut fur Physik komplexer...
Wiley-VCH Verlag GmbH & Co.KGaA, Weinheim, Germany, 2004. — 387 p. — ISBN: 3527307753 This first book dedicated to the topic relates the known physiological functions of porins to their molecular structure and mechanism, as documented by various in vitro and in vivo methods, including the generation of null mutants in mice. For the first time, it brings together biophysical...
Springer, 2013. — 422 p. — (Proteins and Cell Regulation 9) — ISBN: 978-94-007-6069-1 Tetraspanin proteins have recently emerged as a new class of modulators of various processes involving cell surface receptors, including cell migration and invasion, host immune responses, cell-cell fusion, and viral infection. The book summarises recent advances in the fields of biology in...
Springer, 2013. — 1259 p. — (Proteins and Cell Regulation 9) — ISBN: 978-94-007-6070-7 Tetraspanin proteins have recently emerged as a new class of modulators of various processes involving cell surface receptors, including cell migration and invasion, host immune responses, cell-cell fusion, and viral infection. The book summarises recent advances in the fields of biology in...
Textbook (Basic iText). — Milwaukee: University of Wisconsin, 2015. — 350 p. Most introductory science courses start with a discussion of scientific method, and this interactive electronic textbook, or iText is no exception. A key feature of the iText is its focus on experimental support for what we know about cell biology. Having a sense of how science is practiced and how...
Wiley, 2012. — 631 p. NMR is one of the most powerful methods for imaging of biomolecules. This book is the ultimate NMR guide for researchers in the biomedical community and gives not only background and practical tips but also a forward looking view on the future of NMR in systems biology. The Role of NMR in the Study of the Structure and Dynamics of Biomolecules The Role of...
Wiley, 2013. — 487 p. With contributions from an international team of eighty leading experts and pioneers in the field, Production of Plasma Proteins for Therapeutic Use presents a comprehensive overview of the current state of knowledge about the function, use, and production of blood plasma proteins. In addition to details of the operational requirements for the production...
Taylor & Francis Group, 2012. - 278 p. - Molecular recognition, also known as biorecognition, is the heart of all biological interactions. Originating from protein stretching experiments, dynamic force spectroscopy (DFS) allows for the extraction of detailed information on the unbinding process of biomolecular complexes. It is becoming progressively more important in...
Elsevier, 2013. — 351 p. Low-Abundance Proteome Discovery addresses the most critical challenge in biomarker discovery and progress: the identification of low-abundance proteins. The book describes an original strategy developed by the authors that permits the detection of protein species typically found in very low abundance and that may yield valuable clues to future...
Springer, 2018. — 381 p. This edited monograph presents the collected interdisciplinary research results of the priority program “Information- and Communication Theory in Molecular Biology (InKoMBio, SPP 1395)”, funded by the German Research Foundation DFG, 2010 until 2016. The topical spectrum is very broad and comprises, but is not limited to, aspects such as microRNA as part...
3-Volume Set. - Academic Press, 2003. - 2402 p. - The Handbook of Cell Signaling is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses.
8th edition. — Academic Press / Elsevier, 2012. — 1096 p. — ISBN: 978-0-12-374947-5. Basic Neurochemistry: Principles of Molecular, Cellular, and Medical Neurobiology, the outstanding and comprehensive classic text on neurochemistry, is now newly updated and revised in its Eighth Edition. For more than forty years, this text has been the worldwide standard for information on...
Springer, 2017. — 121 p. — ISBN: 978-3-319-60906-5. One of the first “mantras” encountered by non-matrix biologists, as they enter the field of matrix biology, is that the extracellular matrix (ECM) is not simply the glue that holds tissues together. To many matrix biologists, this notion is self-evident; after all, biologists have understood for more than eight decades that...
Springer, 2010. — 321 p. — (Topics in Bone Biology, Volume 6) — ISBN: 978-1-84882-821-6 This volume, the sixth in the series Topics in Bone Biology, presents the current knowledge of bone development, from growth to mineralization.Like previous volumes in this series, it embraces the important interaction between medical science and practice. Insights stemming from molecular...
Springer, 2015. - 90 p. - In this unique overview of the Hsp60 chaperonin, Peter Bross addresses molecular biologists, medical research scientists and individuals interested in molecular or general biology. First, Bross discusses the basics of the Hsp60 chaperonin in terms of its structure and the molecular mechanisms determining its function. Second, the author highlights the...
WIT Press, 2007. — 513 p. This volume focuses initially on DNA as a starting point for the consideration of the evolution of information and complexity in the natural world. The significance of the dual functions of DNA and the complexity of biomolecules, emphatically revealed by results from the Human Genome Project, are considered both in the context of the way living things...
9th Edition. — Glencoe/McGraw-Hill, 2006. — 890 p. BSCS Biology: A Molecular Approach (Blue Version) challenges gifted and honor students to think scientifically, to integrate concepts, to analyze data, and to explore complex issues. This research-based program, developed with funding from the National Science Foundation, supports an inquiry approach to biology. It provides...
Cambridge University Press, 2010. - 283 p. - The science of complex biological networks is transforming research in areas ranging from evolutionary biology to medicine. This is the first book on the subject, providing a comprehensive introduction to complex network science and its biological applications. With contributions from key leaders in both network theory and modern...
Wiley, 2006. - 310 p. - The ability to introduce non-canonical amino acids in vivo has greatly expanded the repertoire of accessible proteins for basic research and biotechnological application. Here, the different methods and strategies to incorporate new or modified amino acids are explained in detail, including a lot of practical advice for first-time users of this powerful...
Wiley, 2009. - 296 p. - The growing flood of new experimental data generated by genome sequencing has provided an impetus for the development of automated methods for predicting the functions of proteins that have been deduced by sequence analysis and lack experimental characterization. Prediction of Protein Structures, Functions and Interactions presents a comprehensive...
2nd Edition. — Academic Press, 2019. — 454 p. — ISBN 978-0-12-813259-3. This book, Second Edition, provides an overview of skeletal biology, from the molecular level, to the organ level, including cellular control, interaction and response, adaptive responses to various external stimuli, and the interaction of the skeletal system with other metabolic processes in the body. The...
Springer, 1998. — 336 p. — ISBN: 978-3-642-72073-4. Life and Death in Stationary Phase The Citric Acid Cycle and Oxygen-Regulated Gene Expression in Escherichia coli Gene Transfer by Bacterial Conjugation: Establishment of the Immigrant Plasmid in the Recipient Cell Bacteriophage Mu Regulation of Bacteriophage λ Replication Replication and Maintenance of Bacterial Plasmids...
Springer, 2018. — 244 p. The book addresses new achievements in AFM instruments – e.g. higher speed and higher resolution – and how AFM is being combined with other new methods like NSOM, STED, STORM, PALM, and Raman. This book explores the latest advances in atomic force microscopy and related techniques in molecular and cell biology. Atomic force microscopy (AFM) can be used...
NTech, 2012. - 484 p. - This book has gathered an ensemble of experts in the field, in 22 chapters, which have been broadly categorized into Computational Approaches, Experimental Approaches, and Others. Computational Approaches Computational Methods for Prediction of Protein-Protein Interaction Sites Advances in Human-Protein Interaction - Interactive and Immersive Molecular...
3rd ed. Textbook, London, ElsieverAcademic Press, 2004, 349 p. Book about DNA structure An Introduction to Molecular Biology for Non-Scientists Why a Helix? Different Kinds of Double Helix Twisting and Curving Curving in Three Dimensions DNA Supercoiling The Assembly of DNA into Chromosomes Specific DNA–Protein Interactions Methods Used to Study the Structure of DNA DNA in...
CRC Press, 2015. - 496 p. - Cell Membrane Nanodomains: From Biochemistry to Nanoscopy describes recent advances in our understanding of membrane organization, with a particular focus on the cutting-edge imaging techniques that are making these new discoveries possible. With contributions from pioneers in the field, the book explores areas where the application of these novel...
Momentum Press, 2017. — 73 p. — (Biology Collection). — ISBN10: 1944749039, ISBN13: 978-1944749033. This book introduces the concept of emergent properties, which are unexpected traits found only when two or more biological components interact. This book introduces the concept of emergent properties, which are unexpected traits found only when two or more biological components...
2000 Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York. Despite the global interest in elucidating mechanisms of transcriptional regulation, a comprehensive source of strategic, conceptual, and technical information has not been available for those entering the field for the first time. Although protocols for numerous techniques have been published, the...
4th Edition. — Academic Press, 2019 (2020). — 271 p. — ISBN: 978-0-12-818024-2. This book, Fourth Edition is a must-have collection of methods and procedures on how to create a single, continuous, comprehensive project that teaches students basic molecular techniques. It is an indispensable tool for introducing advanced undergraduates and beginning graduate students to the...
Oxford University Press, 1998. — 235 p. Silane-modified surfaces for biomaterial immobilization. Avidin-biotin immobilization systems. Antibodies as immobilization reagents. Bioanalytical applications of self-assembled monolayers. Protein adsorption: friend or foe? Micropatterning cell adhesiveness. Sol-gel matrices for protein entrapment. Immobilization of'smart'...
Springer, 2013. — 285 p. Gaining Insights into the Small Molecule Targeting of the G-Quadruplex in the c-MYC Promoter Using NMR and an Allele-Specific Transcriptional Assay, by Christine E. Kaiser, Vijay Gokhale, Danzhou Yang and Laurence H. Hurley. Higher-Order Quadruplex Structures, by Luigi Petraccone. Investigation of Quadruplex Structure Under Physiological Conditions...
2nd edition. — Wolters Kluwer, 2019. — 265 p. — ISBN: 978-1496348500 Now in its second edition, Lippincott Illustrated Reviews: Cell and Molecular Biology continues to provide a highly visual presentation of essential cell and molecular biology, focusing on topics related to human health and disease. It offers all the most popular features of the bestselling Lippincott...
InTech. 2011. — 148 p. This book focuses on the numerous applications of Bacterial Artificial Chromosomes (BACs) in a variety of studies. The topics reviewed range from using BAC libraries as resources for marsupial and monotreme gene mapping and comparative genomic studies, to using BACs as vehicles for maintaining the large infectious DNA genomes of viruses. The large size of...
CRC Press, 2016. - 139 p. - Basics of Molecular Recognition explores fundamental recognition principles between monomers or macromolecules that lead to diverse biological functions. Based on the author’s longtime courses, the book helps readers understand the structural aspects of macromolecular recognition and stimulates further research on whether molecules similar to DNA or...
Springer, 2018. — 359 p. Cell surface small molecules and macromolecules, such as members of cholesterol family (including steroid hormones), the glycolipid family (sphingolipids), the glycoprotein family (both N-linked and O-linked), and a vast array of other receptors have been shown to be involved in normal and abnormal cellular processes. The 11th International Symposium on...
Bentham Science Publishers, 2015. — 147 p. Nucleic acid sequencing techniques have enabled researchers to determine the exact order of base pairs - and by extension, the information present - in the genome of living organisms. Consequently, our understanding of this information and its link to genetic expression at molecular and cellular levels has lead to rapid advances in...
Springer, 2004. — 305 p. — ISBN: 978-3-642-62269-4. This volume consists of papers concerned with models and methods used in solving some fundamental problems of biosciences. They represent a wide spectrum of diverse ideas and trends. In particular, they reflect the genuinely interdisciplinary nature of research on modeling in molecular biology the inspiration, ideas and...
2nd edition. — Academic Cell, 2013. — 928 p. Molecular Biology, Second Edition, examines the basic concepts of molecular biology while incorporating primary literature from today’s leading researchers. This updated edition includes Focuses on Relevant Research sections that integrate primary literature from Cell Press and focus on helping the student learn how to read and...
3rd Edition. — Academic Cell, 2019. — 1001 p. — ISBN: 978-0-12-813288-3. This book, Third Edition, provides a thoroughly revised, invaluable resource for college and university students in the life sciences, medicine and related fields. This esteemed text continues to meet the needs of students and professors by offering new chapters on RNA, genome defense, and epigenetics,...
Elsevier / Academic Press, 2005. — 803 p. This book’s subtitle, Understanding the Genetic Revolution, reflects the massive surge in our understanding of the molecular foundations of genetics in the last fifty years. In the next half century our understanding of how living organisms function at the molecular level, together with our ability to intervene, will expand in ways we...
3rd edition. — New York: Academic Cell, 2019. — 1001 p. Molecular Biology, Third Edition, provides a thoroughly revised, invaluable resource for college and university students in the life sciences, medicine and related fields. This esteemed text continues to meet the needs of students and professors by offering new chapters on RNA, genome defense, and epigenetics, along with...
Elsevier; Academic Cell, 2012. — 816 p. Molecular Biology: Academic Cell Update Edition Study Guide aims to help students get a better grasp of important concepts in Molecular Biology: Academic Cell Update. Each of the chapters in this study guide contains a summary that lets students see the bigger picture, that is, how all the techniques fit together in that chapter. A list...
Wiley, 2000. - 300 p. Recently molecular biology has undergone unprecedented development generating vast quantities of data needing sophisticated computational methods for analysis, processing and archiving. This requirement has given birth to the truly interdisciplinary field of computational biology, or bioinformatics, a subject reliant on both theoretical and practical...
Wiley, 2000. - 307 P. (Wiley series in mathematical and computational biology) Recently molecular biology has undergone unprecedented development generating vast quantities of data needing sophisticated computational methods for analysis, processing and archiving. This requirement has given birth to the truly interdisciplinary field of computational biology, or bioinformatics,...
Springer, 2017. — 269 p. This book focuses on the regulation of transcription and translation in Archaea and arising insights into the evolution of RNA processing pathways. From synthesis to degradation and the implications of gene expression, it presents the current state of knowledge on archaeal RNA biology in 13 chapters. Topics covered include the modification and...
Springer International Publishing, Switzerland, 2016. — 715 p. — ISBN10: 3319407384 For the first time this book compiles chapters comprehensively dealing with extracellular matrices in arthropods from exoskeleton components to glandular matrices such as silks and saliva The unique mechanical properties of arthropod composite matrices have inspired and gained applicative uses...
Humana Press, 2000. — 489 p. P. Michael Conn and Anthony Means have successfully assembled a panel of leading investigators to provide an integrated review of the key areas - membrane receptor-initiated cell signaling and nuclear-receptor initiated gene regulation. Chosen for the excellence of their research, these distinguished authors illuminate the molecular machinery...
W.H.Freeman and Company, 2012. - 948 p. - Written and illustrated with unsurpassed clarity, Molecular Biology: Principles and Practice introduces fundamental concepts while exposing students to how science is done. The authors convey the sense of joy and excitement that comes from scientific discovery, highlighting the work of researchers who have shaped - and who continue to...
Oxford University Press, 2010. - 882 p. - The biological world operates on a multitude of scales - from molecules to cells to tissues to organisms to ecosystems. Throughout all these levels runs a common thread: the communication and onward passage of information - from cell to cell, from organism to organism and, ultimately, from generation to generation. This information is...
Helvetian Press, 2010. - 716 p. The twenty-one chapters of this volume present a comprehensive description for chemists, biologists and students of the fundamental physical and chemical phenomena that form the basis of molecular biology. Topics include the fundamental thermodynamic and kinetic properties of biochemical reactions in solution; the physical properties of aqueous...
Wiley, 2003. - 394 p. - Molecular biology has had a major impact on the practice of pathology in recent years and this continues with the new approaches being developed in genomics and proteomics. Knowledge of the molecular organization of the cell has led to the development of powerful new techniques which bring greater accuracy and objectivity to the diagnosis, prognosis and...
3rd Edition. - CRC Press, 2011. - 721 p. - Several milestones in biology have been achieved since the first publication of the Handbook of Molecular and Cellular Methods in Biology and Medicine. This is true particularly with respect to genome-level sequencing of higher eukaryotes, the invention of DNA microarray technology, advances in bioinformatics, and the development of...
Wiley, 2018. - 570 p. Presenting a wide array of information on chemical ligation – one of the more powerful tools for protein and peptide synthesis – this book helps readers understand key methodologies and applications that protein therapeutic synthesis, drug discovery, and molecular imaging. -Moves from fundamental to applied aspects, so that novice readers can follow the...
Springer Science & Business Media, 2011. — 583 p. The book describes how the balance between pro- and anti-inflammatory molecules is related to health and disease. It is suggested that many diseases are initiated and their progress is influenced by inflammatory molecules and a decrease in the production and/or action of anti-inflammatory molecules and this imbalance between...
InTech, 2016. — 512 p. — ISBN: 9789535124368. In this book eminent scientists provide an up-to-date review of the present and future trends on biofilm-related research. The book provides a comprehensive account on microbial interactions in biofilms, pyocyanin, and extracellular DNA in facilitating Pseudomonas aeruginosa biofilm formation, atomic force microscopic studies of...
Wiley, 2004. - 429 p. - This readily comprehensible book explains the identification of molecular targets via cellular assays, reporter genes or transgenic models, as well as surveying recent advances in the synthesis, separation and analysis of drugs. A special section is devoted to molecular genetics methods. With its examination of these novel methods and generous practical...
Weinheim, Germany: Wiley-VCH Verlag GmbH, 2018. — 432 p. — ISBN: 3527342672. An essential guide that puts the focus on method developments and applications in aptamers In recent years, aptamer-based systems have been developed for a wide-range of analytical and medical applications. Aptamers for Analytical Applications offers an introduction to the topic, outlines the common...
Elsevier, 2014. - 547 p. - Methods in Enzymology 546. - This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers recent research and methods development for changing the DNA sequence within the genomes of cells and organisms. Focusing on enzymes that generate double-strand...
Elsevier, Acad. Press, 2014. — 549 p. — (Methods in Enzymology, Volume 546). — ISBN: 978-0-12-801185-0 This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers recent research and methods development for changing the DNA sequence within the genomes of cells and organisms....
Kluwer, 2000. - 272 p. Plant molecular biology has produced an ever-increasing flood of data about genes and genomes. Evolutionary biology and systematics provides the context for synthesizing this information. This book brings together contributions from evolutionary biologists, systematists, developmental geneticists, biochemists, and others working on diverse aspects of...
Chapman & Hall/CRC. 2003. - 484 p. Technology today allows the collection of biological information at an unprecedented level of detail and in increasingly vast quantities. To reap real knowledge from the mountains of data produced, however, requires interdisciplinary skills-a background not only in biology but also in computer science and the tools and techniques of data...
Lippincott Williams, 1999. - 120 p. - The impact of molecular biology today and in the future cannot be underestimated. Gene therapy and cloning of sheep are explained and discussed in the daily newspapers. The clinical and etiolog- ical aspects of diseases are now being explained at the molecular biology level. Drugs that will have an impact on molecular biological processes...
3rd Edition. - Lippincott Williams & Wilkins, 2012. - 169 p. - High-Yield Cell and Molecular Biology, Third Edition provides the essential information needed for USMLE Step 1 review and course study. It covers current cell and molecular biology techniques and principles with a clinical focus — what a physician needs to know to understand, diagnose, and treat human disease....
Wiley, 2010. - 481 p. - This book covers several major areas of modern research, development, and practical applications of molecular sciences. This text offers empirical-rational principles of broad relevance to scientists, professionals, and students interested in general aspectsof molecular discovery, as well as the thought processes behind experimental approaches. Empirical...
Springer, 1997. — 416 p. In recent years, unprecedented advances in many aspects of the molecular biology of nucleic acids have been witnessed. The area of RNA chemistry has undergone a kind of explosion, with a huge interest in RNA-mediated catalysis. At the same time, our structural understanding of DNA-protein interactions has increased enormously, and the related area of...
Pan Stanford Publishing, 2016. — 471 p. Liposomes have been widely explored in the drug delivery realm over the past decades. Many of the properties that made them well suited for drug delivery applications, such as the internal space to encapsulate a large payload of molecules and the inherent protection from exterior stresses, have also been exploited in various analytical...
John Wiley & Sons, 2016. - 631 p. - ISBN: 978-1-118-89368-5 Pattern recognition is the automatic identification ofregularities, that is, figures, characters, shapes, and forms present in data. Pattern recognition is the core process of many scientific discoveries, whereby researchers detect regularities in large amounts of data in fields as diverse as Geology, Physics,...
Springer, 2005. — 238 p. The book provides an updated overview of molecular analysis of human tissues, and the impact this analysis has on diagnosis and prognosis of human diseases. Special emphasis is placed on human cancer and the future directions of the field. Methods of handling clinical tissue samples, including the impact of handling on subsequent molecular analysis, are...
Springer, 2015. - 353 p. - The aim of molecular diagnostics is preferentially to detect a developing disease before any symptoms appear. There has been a significant increase, fueled by technologies from the human genome project, in the availability of nucleic acid sequence information for all living organisms including bacteria and viruses. When combined with a different type...
Springer, 2012. - 261 p. - Infrared spectroscopy is a new and innovative technology to study protein folding/misfolding events in the broad arsenal of techniques conventionally used in this field. The progress in understanding protein folding and misfolding is primarily due to the development of biophysical methods which permit to probe conformational changes with high kinetic...
Elsevier, 2014. - 242 p. - Biomolecular Electronics - the electrical control of biological phenomena - is a scientific challenge that, once fully realized, will find a wide range of applications from electronics and computing to medicine and therapeutic techniques. This new arena of biomolecular electronics is approached using familiar concepts from many areas such as...
Academic Press, 2020. — 571 p. — ISBN: 9780128191781 Precision Medicine for Investigators, Practitioners and Providers addresses the needs of investigators by covering the topic as an umbrella concept, from new drug trials to wearable diagnostic devices, and from pediatrics to psychiatry in a manner that is up-to-date and authoritative. Sections include broad coverage of...
4th Edition. — Elsevier, 2010. — 742 p. This is the fourth edition of the successful laboratory guide which has translated the rich story of riboneucleic acid for over fifteen years. RNA Methodologies 4e presents the latest collection of tested laboratory protocols for the isolation and characterization of eukaryotic and prokaryotic RNA with greater emphasis on transcript...
Wiley, 2006. - 290 p. This keenly awaited first overview of the field represents a complete guide to the structure and function of the most important mammalian cell membrane organelles. Filling a huge gap in the primary literature, this book is the first to cover the subject in detail. Following an introduction by Kai Simons, the discoverer of lipid rafts and the most prominent...
John Wiley & Sons, Inc., 2003. — 470 p. The past few years have witnessed rapid progress in the characterization of mechanisms that underlie the generation and processing of inter- and intracellular signals. While there have been significant corollary advances in the area of signaling in disease processes, there is as yet no single resource that connects these advances with an...
Cambridge University Press, 2011. - 287 p. - The concept of molecular machines in biology has transformed the medical field in a profound way. Many essential processes that occur in the cell, including transcription, translation, protein folding, and protein degradation, are all carried out by molecular machines. This volume focuses on important molecular machines whose...
InTech, 2012. - 772 p. - This volume will help new investigators in the field to get acquainted with the general topic of lipoprotein research and will guide scientists interested in this area to emerging new fields. By typing into databases such as Medline or PubMed the word "lipoprotein" one gets more than 100.000 hits that highlight the common interest in this topic. It is...
2nd Edition. — Springer, 2008. — 2847 p. Glycostructures play a pivotal and crucial role in a myriad of organisms and important systems in biology, physiology, medicine, bioengineering and technology. Within recent years tools have been developed to promote the understanding of their highly complex functions and the associated chemistry and chemical biology, however, many facts...
2nd Edition. - Wiley, 2011. - 459 p. - Molecular Ecology, 2nd Edition provides an accessible introduction to the many diverse aspects of this subject. The book takes a logical and progressive approach to uniting theory with examples from a wide range of taxonomic groups. The straightforward writing style offers in-depth analysis whilst making often challenging subjects such as...
The Royal Society of Chemistry, 2013. — 357 p. Guanosine and its derivatives have a high potential for self-recognition and self-assembly, as well as the recognition ability for other biologically important molecules. This book explores in detail these properties with the goal of increasing knowledge of the basic principles of guanosine-assembly, synthesis of new optimised...
Elsevier, 2009. - 534 p. - The 33rd volume of Laboratory Techniques in Biochemistry and Molecular Biology Series reviews the techniques Forster Resonance Energy Transfer (FRET) and Fluorescence Lifetime Imaging Microscopy (FLIM) providing researchers with step by step protocols and handy hints and tips. Both have become staple techniques in many biological and biophysical...
John Wiley & Sons, Inc., 2008. - 737 p. Current Protocols Essential Laboratory Techniques (CPET) is a fundamentally new type of laboratory manual. This manual thus serves as a companion for more advanced technical manuals, such as the other titles in the Current Protocols series, and is a basic standard reference for any molecular laboratory. As this manual covers technical...
Springer, 2011. — 348 p. — ISBN: 978-94-007-0427-5. Cellular lesions are related to macromolecular synthetic processes including the hierarchical flow of genetic information. Heavy metals generate oxidizing radicals through the Fenton and Haber-Weiss reactions leading to metal-induced carcinogenesis mediated primarily by the elevated levels of reactive oxygen species. Heavy...
CRC Press, 2009. — 424 p. Endogenous small RNAs have been found in various organisms, including humans, mice, flies, worms, fungi, and bacteria. Furthermore, it’s been shown that microRNAs acting as cellular rheostats have the ability to modulate gene expression. In higher eukaryotes, microRNAs may regulate as much as 50 percent of gene expression. Regulation of Gene Expression...
Wiley-Liss, 2001. - 542 p. Preparing for Success in the Laboratory Getting What You Need from a Supplier The Preparation of Buffers and Other Solutions: A Chemist’s Perspective How to Properly Use and Maintain Laboratory Equipment Working Safely with Biological Samples Working Safely with Radioactive Materials DNA Purification RNA Purification Restriction Endonucleases...
Academic Press, 2020. — 372 p. — ISBN: 978-0-12-816126-5. This book enables the reader to understand the role of sialylation as a post translational modification. The book provides insights on the latest knowledge in the field of sialoglycobiology. Sialic acids as terminal residues of oligosaccharide chains play crucial roles in several cellular recognition events. Synthesized...
2nd Edition. — Cold Spring Harbor Laboratory Press, 2005. — 929 p. Dynamic modulation of protein–protein interactions provides the physical basis for many biological signaling networks. Consequently, over the last several decades, much effort has been invested in defining and understanding these interactions. Knowledge of the pattern and regulation of discrete protein–protein...
Taylor and Francis Group, 2011. - 301 p. - The role of metal ions in protein folding and structure is a critical topic to a range of scientists in numerous fields, particularly those working in structural biology and bioinorganic chemistry, those studying protein folding and disease, and those involved in the molecular and cellular aspects of metals in biological systems....
Springer, 2012. - 508 p. - Since the discovery of X-rays and radioactivity, ionizing radiations have been widely applied in medicine both for diagnostic and therapeutic purposes. The risks associated with radiation exposure and handling led to the parallel development of the field of radiation protection. Pioneering experiments done by Sanche and co-workers in 2000 showed that...
2nd Edition. - Elsevier, 2009. - 839 p. - Signal Transduction is a well-illustrated, coherent look at cellular signaling processes. Beginning with the basics, it explains how cells respond to external cues, hormones, growth factors, cytokines, cell surfaces, etc., and then shows how these inputs are integrated and coordinated. The extensive color artwork provides the reader...
Academic Press, 2003. — 441 p. — ISBN: 978-0122896316 Signal Transduction is a well-illustrated, coherent look at cellular signaling processes. Beginning with the basics, it explains how cells respond to external cues, hormones, growth factors, cytokines, cell surfaces, etc., and then shows how these inputs are integrated and coordinated. The extensive color artwork provides...
Springer, 2016. - 180 p. - This book will take an evidence-based approach to current knowledge about biomolecules and their place in our lives, inviting readers to explore how we know what we know, and how current gaps in knowledge may influence the way we approach the information. Biomolecular science is increasingly important in our everyday life, influencing the choices we...
New York: Copernicus, 1996. - 183 p. The molecular world Looking at the molecular world The names of molecules Molecular building blocks Building molecules Enzymes Information Powering the body Digestion Chemical energy Form and motion Cell form Body form Molecular motors Dangers and defenses Toxins and venoms Detoxification Immunity Healing Molecules and the mind Hormones...
2nd Edition. — Springer, 2009. — 171 p. Imagine that we had some way to look directly at the molecules in a living organism. An x-ray microscope would do the trick, or since we’re dreaming, perhaps an Asimov-style nanosubmarine (unfortunately, neither is currently feasible). Think of the wonders we could witness firsthand: antibodies atta- ing a virus, electrical signals racing...
Springer Nature Singapore Pte Ltd., 2017. — 86 p. — (SpringerBriefs in Applied Sciences and Technology) — ISBN: 9811046352. This book highlights the experimental investigations that have been carried out on magnetic resonance imaging and computed tomography (MRI & CT) images using state-of-the-art Computational Image processing techniques, and tabulates the statistical values...
Springer. 2011. 363 p. Being the crucial components of living cells, ion channels are important targets of therapeutic agents. Historically, it has been challenging to develop drugs on this target class. A major issue with target based ion channel drug development is the identification of effective small chemical leads for medicinal chemistry optimization to the clinical...
Springer, 2015. - 270 p. - Protein conversion from a water-soluble native conformation to the insoluble aggregates and fibrils, which can deposit in amyloid plaques, underlies more than 20 human diseases, representing a major public health problem and a scientific challenge. Such a conversion is called protein misfolding. Protein misfolding can also involve errors in the...
John Wiley & Sons Ltd, West Sussex, UK, 2009. — 543 p. — ISBN: 1405176296 Metal ions and metal complexes have long been recognized ascritically important components of nucleic acid chemistry, both inregulation of gene expression and as promising therapeutic agents.Understanding how metal complexes interact with DNA has become anactive research area at the interface between...
Third Edition. — Oxford University Press, 2010. - 292 p. ISBN An overview of signalling Aspects of cellular signalling Pathways are the key to signalling A look at some of the history and techniques of cell signalling Components that comprise signalling pathways Extracellular signals: hormones, cytokines and growth factors Detection of extracellular signals: the role of...
Wiley, 2012. — 673 p. Tag-based approaches were originally designed to increase the throughput of capillary sequencing, where concatemers of short sequences were first used in expression profiling. New Next Generation Sequencing methods largely extended the use of tag-based approaches as the tag lengths perfectly match with the short read length of highly parallel sequencing...
Springer, 2018. — 464 p. This edited book contains a compilation of 14 advanced academic chapters dealing with the structure and function of membrane protein complexes. This rapidly advancing important field of study closely parallels those on soluble protein complexes, and viral protein and nucleoprotein complexes. Diverse topics are included in this book, ranging from...
Taylor & Francis Group, 2014. - 474 p. - Interest in the role of extracellular vesicles (microvesicles and exosomes) is expanding rapidly. It is now apparent that far from being merely cellular debris, these vesicles play a key role in cell-to-cell communication and signaling. Moreover, they are significantly elevated in a number of diseases. This raises the question of their...
Wiley-Blackwell, 2019. — 342 p. — ISBN: 978-1-119-38532-5. A groundbreaking text that highlights the various sources, applications and advancements concerning proteins from novel and traditional sources This book offers a guide to the various sources, applications, and advancements that exist and are currently being researched concerning proteins from novel and traditional...
Springer, 2008. — 815 p. Synapses play a central role in the brain by mediating signal transmission between neurons. This book provides a fundamental description of the synapse by leading experts in the field. Each individual synapse carries out its numerous functions in a tiny space, thereby requiring an exquisite molecular and functional arrangement. This book describes the...
Intech, 2012. — 598 p. This book is intended to present current concepts in molecular biology with the emphasis on the application to animal, plant and human pathology, in various aspects such as etiology, diagnosis, prognosis, treatment and prevention of diseases as well as the use of these methodologies in understanding the pathophysiology of various diseases that affect...
Wiley, 2012. - The first and only book devoted entirely to MEMBRANE LIPID ASYMMETRY AND ITS BIOLOGICAL IMPLICATIONS Transmembrane Dynamics of Lipids is comprised of contributions from expert authors from leading research groups that present up-to-date quantitative data on the formation, stability, and biological consequences of the asymmetrical organization of lipids in cell...
CRC Press, 2018. — 225 p. This book endeavours to present an analysis of the current knowledge of the structure properties and possible functions of histones. The broad scope of this topic prevents the discussion of certain individual aspects in any detail. For this purpose, some of the more specialised review articles should be consulted. However, the present volume will...
Popular edition. The molecules of life: DNA, RNA, and proteins / Russ Hodge ; foreword by Nadia Rosenthal. 2009, 240 p. The Physics and Chemistry of Life: Basic Principles and Methods How the Cell Stores and Uses Information Communication Between and Inside Cells Traffic and Cell Architecture Molecules of Immunity, Health, and Disease
Springer, 2005. - 315 p. - Volume 3 of Springer Series on Fluorescence "Fluorescence Spectroscopy in Biology: Advanced Methods and their Applications to Membranes, Proteins, DNA, and Cells" focuses on brandnew research and applications in biology, biophysics and other fields of life sciences. Many frontline researcher have contributed to this highly attractive and...
Basic Books, 2012. - 288 p. - Life is an enduring mystery. Yet, science tells us that living beings are merely sophisticated structures of lifeless molecules. If this view is correct, where do the seemingly purposeful motions of cells and organisms originate? In Life’s Ratchet, physicist Peter M. Hoffmann locates the answer to this age-old question at the nanoscale. Below the...
Cambridge University Press, 2014. - 227 p. - Delivering fundamental insights into the most popular methods of molecular analysis, this text is an invaluable resource for students and researchers. It encompasses an extensive range of spectroscopic and spectrometric techniques used for molecular analysis in the life sciences, especially in the elucidation of the structure and...
Springer, 2018. — 124 p. This book offers comprehensive information on all aspects of ELISA, starting with the fundamentals of the immune system. It also reviews the history of analytical assays prior to the advent of ELISA (enzyme-linked immunosorbent assay) and addresses the materials of choice for the fabrication of the platforms, possible biomolecular interactions,...
Springer, 2014. - 427 p. - In this book, plant biology is considered from the perspective of plants and their surrounding environment, including both biotic and abiotic interactions. The intended audience is undergraduate students in the middle or final phases of their programs of study. Topics are developed to provide a rudimentary understanding of how plant-environment...
World Scientific Pub Co Inc., 2005, 144 p. This book introduces an approach to protein folding from the point of view of kinetic theory. There is an abundance of data on protein folding, but few proposals are available on the mechanism driving the process. Here, presented for the first time, are suggestions on possible research directions, as developed by the author in...
Author: Lawrence Hunter. Published in: Artificial intelligence and molecular biology. One of the major challenges for computer scientists who wish to work in the domain of molecular biology is becoming conversant with the daunting intricacies of existing biological knowledge and its extensive technical vocabulary. Questions about the origin, function, and structure of living...
AAAI Press, 1993. — 467 p. The enormous amount of data generated by the Human Genome Project and other large-scale biological research has created a rich and challenging domain for research in artificial intelligence. These original contributions provide a current sampling of AI approaches to problems of biological significance; they are the first to treat the computational...
Springer, 2013. — 281 p. — (Topics in Current Chemistry 328). Assisting Oxidative Protein Folding: How Do Protein Disulphide-Isomerases Couple Conformational and Chemical Processes in Protein Folding? Peptide Bond cis/trans Isomerases: A Biocatalysis Perspective of Conformational Dynamics in Proteins Small Heat-Shock Proteins: Paramedics of the Cell Allostery in the Hsp70...
Langes Bioscience, 2006. - 286 p. This volume is unique to the existing literature in the Peptide Nucleic Acid field, in that it focuses on comparing and contrasting PNA with other available oligonucleotide homologues and considers areas in which these biomolecules could be profitably applied to clinical and diagnostic applications. Part I of the book addresses comparative...
Springer-Verlag US, 2006. — XX, 274 p. This volume is unique to the existing literature in the Peptide Nucleic Acid field, in that it focuses on comparing and contrasting PNA with other available oligonucleotide homologues and considers areas in which these biomolecules could be profitably applied to clinical and diagnostic applications. Part I of the book addresses comparative...
Wiley, 2011. - 290 p. Addressing one of the biggest riddles in current molecular cell biology, this ground-breaking monograph builds the case for the crucial involvement of lipids and membranes in the formation of amyloid deposits. Tying together recent knowledge from in vitro and in vivo studes, and built on a sound biophysical and biochemical foundation, this overview brings...
Wiley-VCH, 2009. — 371 p. — ISBN: 978-3-527-32265-7. With its exploration of the scientific and technological characteristics of systems exploiting molecular recognition between synthetic materials, such as polymers and nanoparticles, and biological entities, this is a truly multidisciplinary book bridging chemistry, life sciences, pharmacology and medicine. The authors...
CMLS Cellular and Molecular Life Sciences, 2005 Abstract. Phosphodiesterases (PDEs) are essential regulators of cyclic nucleotide signaling with diverse physiological functions. Because of their great market potential and therapeutic importance, PDE inhibitors became recognized as important therapeutic agents in the treatment of various diseases. Currently, there are seven PDE...
MJP Publishers, 2009. — 468 p. — ISBN: 978-81-8094-057-6. The term molecular biology was first used in 1945 by William Astbury. He defined this branch of science as the study of the chemical and physical structures of biological macromolecules. After several breakthroughs in this study, the concept of molecular biology was modified. It can be defined as the biochemistry of...
Springer International Publishing, Switzerland, 2017. — 652 p. — (Reference Series in Phytochemistry) — ISBN: 9783319286686. This handbook provides comprehensive reference information on the efficient production of secondary metabolites from plants by transgenesis and other genetic manipulation strategies. It reviews and summarizes selected important case studies in genetic...
World Scientific Publishing Europe Ltd, 2017. — 610 p. — ISBN10: 1848166605, ISBN13: 978-1848166608. This book represents the results of 45 years of research on a wide range of topics, including atomic physics, single-molecule enzymology, whole-cell metabolism, physiology, pharmacology, linguistics, semiotics, and cosmology. It describes the first comprehensive molecular theory...
Springer, 2012. — 280 p. — (Springer Series on Fluorescence 11). — ISBN: 3642233716. Fluorescent proteins are intimately connected to research in the life sciences. Tagging of gene products with fluorescent proteins has revolutionized all areas of biosciences, ranging from fundamental biochemistry to clinical oncology, to environmental research. The discovery of the Green...
Springer, 2012. — 284 p. Fluorescent proteins are intimately connected to research in the life sciences. Tagging of gene products with fluorescent proteins has revolutionized all areas of biosciences, ranging from fundamental biochemistry to clinical oncology, to environmental research. The discovery of the Green Fluorescent Protein, its first, seminal application and the...
Humana Press, 2017. - 616 p. This book will focus on DNA and histone methylation in epigenetics and describe how it is involved in the molecular mechanisms responsible for the development of cancer. Chapters will summarize the current knowledge of the molecular basis of DNA and histone methylation and explain how it is involved in cancer, describe the features of DNA and...
Humana Press, 2018. — 553 p. — (Methods in Molecular Biology). — ISBN: 1493977768, 9781493977765. This volume explores and explains how digital PCRs (dPCRs) help in the study of numerous topics, such as infectious diseases, evolution of cancer and treatment responses, somatic mosaicism, genome editing and cell therapy, and food testing for GMOs and pathogens. Written in the...
6th Edition. — Wiley, 2010. — 837 p. The sixth edition explores core concepts in considerable depth and presents experimental detail when it helps to explain and reinforce the concepts. The majority of discussions have been modified to reflect the latest changes in the field. The book also builds on its strong illustration program by opening each chapter with VIP art that...
7th Edition. — Wiley, 2013. — 874 p. This Seventh Edition connects experimental material to key concepts of Cell Biology. The text offers streamlined information that reinforces a connection of key concepts to experimentation. Though the use paired art, and new science illustrations, readers benefit from a visual representation of experimental connections. Animations and video...
8th.ed. — Wiley, 2015. — 832 p. — ISBN: 9781118886144. This text is an unbound, three hole punched version. Designed for courses in Cell Biology offered at the Sophomore/Junior level, Karp's Cell and Molecular Biology: Concepts and Experiments, Binder Ready Version, 8th Edition continues to be the best book in the market at connecting key concepts to the experiments that reveal...
Wiley, 2015. - 393 p. - By integrating technology, supporting infrastructure and efficient application, this all-in-one guide presents molecular diagnostics as an essential component of modern, personalized clinical practice. It considers all important aspects, from the hardware and software needed, to recent improvements in blood- and non-blood-based biomarker tests. Chapters...
CRC Press, 2003. — 420 p. — ISBN: 0849314267 Combining elements of biochemistry, molecular biology, and immunology, artificial DNA can be employed in a number of scientific disciplines. Some of the varied applications include site-specific mutagenesis, hybridization, amplification, protein engineering, anti-sense technology, DNA vaccines, protein vaccines, recombinant...
Springer, 2010. - 237 p. - Extracellular nucleic acids have recently emerged as important players in the fields of biology and the medical sciences. In the last several years, extracellular nucleic acids have been shown to be involved in not only microbial evolution as genetic elements but also to have structural roles in bacterial communities, such as biofilms. Circulating DNA...
Springer, 2014. - 355 p. - This book will focus on new molecular interactions and novel activities and the associated diseases that have been recently discovered from the studies of eukaryotic and mammalian aminoacyl-tRNA synthetases. In addition, the potential applications of ARS researches in biotechnology and medicine will be addressed.
CRC Press, 2017. – 541 p. – ISBN: 9781498709613. Marine glycobiology is the study of carbohydrate and carbohydrate with molecules (protein, lipids, enzymes, or small molecules). Glycoconjugates are glycan linked with other biological molecules. The study and research on marine glycobiology is less well-known. However, the recent development on analytical instruments and...
Elsevier, 2012. - 641 p. - Research on dyneins has a direct impact on human diseases, such as viruses and cancer. With an accompanying website showing over 100 streaming videos of cell dynamic behavior for best comprehension of material, Dynein: Structure, Biology and Disease is the only reference covering the structure, biology and application of dynein research to human...
Walter de Gruyter GmbH, 2013. — 431 p. While structure-function relationships of proteins have been studied for a long time, structural studies of RNA face additional challenges. Nevertheless, with the continuous discovery of novel RNA molecules with key cellular functions and of novel pathways and interaction networks, the need for structural information of RNA is still...
Elsevier, 2009. — 353 p. Single molecule techniques, including single molecule fluorescence, optical tweezers, and scanning probe microscopy, allow for the manipulation and measurement of single biological molecules within a live cell or in culture. These approaches, amongst the most exciting tools available in biology today, offer powerful new ways to elucidate biological...
Springer, 2004. — 213 p. — ISBN: 978-3-662-05388-1. Estrogens: From Classical Endocrine Action to Tissue Selective Action Identification of RIP140 as a Nuclear Receptor Cofactor with a Role in Female Reproduction A Structural Explanation for ERα/ERβ SERM Discrimination Protein Structure-Based Design, Synthesis Strategy and In Vitro Pharmacological Characterization of Estrogen...
CRC Press, 2017. — 343 p. Calcium Entry Channels in Non-Excitable Cells focuses on methods of investigating the structure and function of non-voltage gated calcium channels. Each chapter presents important discoveries in calcium entry pathways, specifically dealing with the molecular identification of store-operated calcium channels which were reviewed by earlier volumes in the...
3rd Edition. — Academic Press, 2016. — 1103 p. A reference on cellular signaling processes, the third edition of Signal Transduction continues in the tradition of previous editions, in providing a historical overview of how the concept of stimulus-response coupling arose in the early twentieth century and shaped our current understanding of the action of hormones, cytokines,...
Wiley, 2009. - 389 p. - Your hands-on study guide to the inner world of the cell Need to get a handle on molecular and cell biology? This easy-to-understand guide explains the structure and function of the cell and how recombinant DNA technology is changing the face of science and medicine. You discover how fundamental principles and concepts relate to everyday life. Plus, you...
Springer, 2017. — 172 p. This book focuses on a topical and timely aspect of prokaryotic biology - the biology of prokaryotic multiple chaperonins. Chaperonins are a class of molecular chaperones, the proteins that assist folding of other proteins in the cell. The book begins with an introductory chapter on the structural and functional aspects of chaperonins, followed by an...
Sprinter, 2019. — 276 p. — ISBN: 9811366004. This book will consider principles of the organization of protein molecules, the relationships between primary, secondary, and tertiary structure, the determinants of protein conformation, and the applications of structure determination and structure modeling in biomedical research. Proteins and Protein Structure Conformational...
InTech. 2011. 318 p. DNA replication, the process of copying one double stranded DNA molecule to produce two identical copies, is at the heart of cell proliferation. This book highlights new insights into the replication process in eukaryotes, from the assembly of pre-replication complex and features of DNA replication origins, through polymerization mechanisms, to propagation...
2nd Edition. — ExLi4EvA, 2016. — 311 p. — ISBN: 9533077751 This book covers a wide range of aspects and issues related to the field of DNA replication. The reader will gain an overview of our current understanding of DNA replication and related cellular processes, and useful resources for further reading. Since the discovery of the DNA structure researchers have been highly...
Springer, 2011. - 321 p. - Due to their novel concepts and extraordinary high-throughput sequencing capacity, the next generation sequencing methods allow scientists to grasp system-wide landscapes of the complex molecular events taking place in various biological systems, including microorganisms and microbial communities. These methods are now being recognized as essential...
Wiley Blackwell, 2014. — 536 p. — ISBN: 978-3-527-33465-0 Natural products (secondary metabolites) which once were focused on alkaloids and terpenes nowcover an infinitemolecular diversity, and are merging with primary metabolites through omics connections. Today, it is assumed that druggable molecules can also be a matter of bioinspired thinking through close and synergistic...
5th Edition. — Elsevier, 2013. — 748 p. An expanded, up-to-date resource for students and researchers, The Dictionary of Cell & Molecular Biology, Fifth Edition, provides clear and concise definitions needed for laboratory study. With over 12,000 entries and a breadth of terms across bioscience, including plant molecular biology, microbiology and biotechnology, this revision...
Academic Press, Elsevier, 2007, 455 p. The over 10,000 entries in this comprehensive Dictionary of Cell and Molecular Biology provide clear and concise definitions for anyone working in life sciences today. It incorporates related terms from neuroscience, genetics, microbiology, immunology, pathology, and physiology. This fourth revised edition reflects the enormous changes...
Taylor and Francis Group, 2010. - 562 p. - Carotenoids are of great interest due to their essential biological functions in both plants and animals. However, the properties and functions of carotenoids in natural systems are surprisingly complex. With an emphasis on the chemical aspects of these compounds, Carotenoids: Physical, Chemical, and Biological Functions and Properties...
Springer Science+Business Media, 2006. — 127 p Lappalainen Pekka is a research director at Institute of Biotechnology, University of Helsinki, Finland. His main research interests include the small actin binding proteins twinfilin, Srv2/CAP and ADF/cofilin as well as the analysis of the roles of the actin cytoskeleton during various cellular and developmental processes. He...
Wiley, 2006. - 678 p. - An extensive compilation of articles by leading professionals, this reference explains the fundamental principles of mass spectrometry as they relate to the life sciences. Topics covered include spectroscopy, energetics and mechanisms of peptide fragmentation, electron capture dissociation, ion-ion and ion-molecule reactions, reaction dynamics,...
Elsevier, 1998. — 375 p. Understanding the mechanisms of eukaryotic gene regulation is essential for students and scientists working in a wide range of clinical and basic disciplines. However, keeping track of the vast number of transcription factors which are central to gene regulation can prove daunting. The fourth edition of Eukaryotic Transcription Factors not only provides...
Springer, 2019. — 299 p. — (Topics in Medicinal Chemistry 30). – ISBN: 978-3-030-24589-4. This book introduces readers to the latest advances in G protein-coupled receptor (GPCR) biology. It reviews our current understanding of the structural basis of ligand binding and allosteric mechanisms, following a decade of technological breakthroughs. Several examples of structure-based...
CRC Press, 2010. - 450 p. - Computational modeling can provide a wealth of insight into how energy flow in proteins mediates protein function. Computational methods can also address fundamental questions related to molecular signaling and energy flow in proteins. Proteins: Energy, Heat and Signal Flow presents state-of-the-art computational strategies for studying energy...
CRC Press, 2013. - 333 p. - Lipidomics is the study of the lipid molecules that are found in animal, plant, and bacterial cells. Recent research in this field has been driven by the development of sensitive new mass spectrometric tools and protocols, leading to the identification and quantification of thousands of lipids and their roles in metabolic processes. Designed for...
3rd edition. — Academic Press, 2019. — 628 p. — ISBN: 978-0-12-813209-8 The Ovary, Third Edition, includes more than 60% new material that highlights the clinical aspects of human ovarian functions. It covers advances in the areas of genomics, assisted reproductive technology, and cancer diagnosis and treatment. This updated edition synthesizes new information at the molecular,...
Springer Nature Singapore Pte Ltd., 2017. — 238 p. — (Advances in Experimental Medicine and Biology 983) — ISBN: 9811043094. RNA is a class of versatile nucleic acid molecules with a myriad of functions, and being able to base pair with both DNA and RNA, it is naturally used by organisms as a guide tool to specifically target proteins to other nucleic acid sequences as...
2nd Edition. — Springer-Verlag, Berlin, Heidelberg, 2017. — 588 p. — (Springer Protocols) — ISBN10: 3662529572 his manual offers detailed protocols for fluorescence in situ hybridization (FISH) and comparative genomic hybridization approaches, which have been successfully used to study various aspects of genomic behavior and alterations. Methods using different probe and cell...
Springer, 2009. - 451 p. - This FISH application guide provides an overview of the principles and the basic techniques of fluorescence in situ hybridization (FISH) and primed in situ hybridization (PRINS), which are successfully used to study many aspects of genomic behavior and alterations. In 36 chapters, contributed by international experts in their particular field, the...
Cambridge University Press, 2005. — 305 p. This monograph describes the theoretical bases and experimental prerequisites for methods such as spin fluorescence, triplet, Mössbauer, photochromic and electron-density labeling, including the procedures used to obtain specifically modified proteins, enzymes, biomembranes, nucleic acids, and other biological molecules. The...
2nd Edition. - World Scientific Publishing, 2013. - 495 p. - This highly illustrated book provides an up-to-date description of the structure and function of the translation system including ribosomes, tRNAs, translation factors, antibiotics and aminoacyl-tRNA synthetases. Research on translation is undergoing rapid changes and is receiving significant attention as evidenced by...
World Scientific Publishing Company, 2014. — 204 p. — ISBN: 978-9814579544 (pbk. : alk. paper), ISBN: 9814579548 (pbk. : alk. paper) Synthetic Biology: A Lab Manual is the first manual for laboratory work in the new and rapidly expanding field of synthetic biology. Aimed at non-specialists, it details protocols central to synthetic biology in both education and research. In...
7th edition — Freeman, W. H. & Company, 2013. — 1154 p. — ISBN-10: l-4292-3413-X, ISBN-13: 978-1-4292-3413-9 Molecular Cell Biology presents the key concepts in cell biology and their experimental underpinnings. The authors, all world-class researchers and teachers, incorporate medically relevant examples where appropriate to help illustrate the connections between cell biology...
6th Edition. — Freeman, W. H. & Company, 2007. — 1150 p. ISBN10: 1429209569, ISBN13: 978-1429209564 With its acclaimed author team, cutting-edge content, and coverage based on landmark experiments, Molecular Cell Biology has earned an impeccable reputation with instructors, edition after edition. The new Sixth Edition is the Molecular Cell Biology for a new generation, a...
6th Edition. — Freeman, W. H. & Company, 2007. — 1150 p. ISBN10: 1429209569, ISBN13: 978-1429209564 With its acclaimed author team, cutting-edge content, and coverage based on landmark experiments, Molecular Cell Biology has earned an impeccable reputation with instructors, edition after edition. The new Sixth Edition is the Molecular Cell Biology for a new generation, a...
7th edition — Freeman, W. H. & Company, 2013. — 1154 p. ISBN-10: l-4292-3413-X, ISBN-13: 978-1-4292-3413-9 Molecular Cell Biology presents the key concepts in cell biology and their experimental underpinnings. The authors, all world-class researchers and teachers, incorporate medically relevant examples where appropriate to help illustrate the connections between cell biology...
7th edition — Freeman, W. H. & Company, 2013. — 1154 p. ISBN-10: l-4292-3413-X, ISBN-13: 978-1-4292-3413-9 Molecular Cell Biology presents the key concepts in cell biology and their experimental underpinnings. The authors, all world-class researchers and teachers, incorporate medically relevant examples where appropriate to help illustrate the connections between cell biology...
8th Edition. - W. H. Freeman and Company, 2016. - 1278 p. - With its acclaimed author team, cutting-edge content, emphasis on medical relevance, and coverage based on key experiments, "Molecular Cell Biology" has justly earned an impeccable reputation as an exciting and authoritative text. Avoiding an encyclopedic approach, the book grounds its coverage in the experiments that...
(5th edition) Authors: Lodish H., Berk A., Matsudaira P., Kaiser C. A., Krieger M., Scott M. P., Zipursky L., Darnell J. W.H. Freeman, 2003. - 973 p. This is a book in English. It describes the structure of the cell and the processes occurring in it.. Life Begins with Cells Chemical Foundations Protein Structure and Function From Gene to Protein: Basic Molecular Genetic...
Oxford University Press, 1999. — 358 p. No one can escape a sense of wonder when looking at an organism from within. From the humblest amoeba to man, from the smallest cell organelle to the amazing human brain, life presents us with example after example of highly ordered cellular matter, precisely organized and shaped to perform coordinated functions. But where does this order...
Springer, 2012. - 334 p. - Biological systems are an emerging discipline that may provide integrative tools by assembling the hierarchy of interactions among genes, proteins and molecular networks involved in sensory systems. The aim of this volume is to provide a picture, as complete as possible, of the current state of knowledge of sensory systems in nature. The presentation...
Wiley, 2012. — 329 p. This book is a comprehensive and up-to-date review and evaluation of the contemporary status of telomerase research. Chapters in this volume cover the basic structure, mechanisms, and diversity of the essential and regulatory subunits of telomerase. Other topics include telomerase biogenesis, transcriptional and post-translational regulation, off-telomere...
Wiley, 2018. — 223 p. — ISBN: 978-1-119-28121-4. A basic overview of mass spectrometry relevant to life and health science applications, illustrated throughout with relevant case studies. This introductory text provides information and assistance to new users of mass spectrometry (MS) working in clinical or biochemical fields who are faced with implementing and designing...
Academic Press, 2019. — 368 p. — ISBN: 978-0-12-815669-8. The ‘RNA world’ hypothesis that proposed RNA molecules as the first form of genetic material was put forwarded in the late 1980s but got impetus only recently when high-throughput sequencing technologies began unearthing new types of non-coding RNA (ncRNA) transcripts in higher eukaryotes. Till then, research on ncRNAs...
Springer, 2013. - 166 p. - "Disruption of Protein-Protein Interfaces" reviews the latest developments and future perspectives in drug discovery at protein-protein interfaces. The authors detail experimental and computational tools to tackle the subject and highlight the contribution of the Italian research community to the field. Evidence shows that blocking or modulating...
Springer, 2017. — 581 p. — Advances in Experimental Medicine and Biology, volume 1042. — ISBN: 978-981-10-6955-0/ This book reviews the latest trends and future directions of DNA replication research. The contents reflect upon the principles that have been established through the genetic and enzymatic studies of bacterial, viral, and cellular replication during the past...
Second Edition. — Academic Press, 1999. — 647 p. Biological Techniques Series The book describes various aspects of the use of fluorescent and luminescent dyes in cell and molecular biology. It will be useful for those who are engaged in confocal microscopy, the study of the visualization of the membrane potential of living cells, GFP proteins. The use of fluorescent and...
Springer, 2013. - 92 p. - The goal of this book is to introduce the biological and technical aspects of next generation sequencing methods, as well as algorithms to assemble these sequences into whole genomes. The book is organized into two parts; part 1 introduces NGS methods and part 2 reviews assembly algorithms and gives a good insight to these methods for readers new to...
Springer Nature Singapore Pte Ltd., 2018. — 286 p. — ISBN: 978-981-10-8371-6. The focus of this book is to introduce up-to-date information on applications and practical use of RNA for agriculture, biotechnology and medicine. It provides unique ideas, tools, and methods in detail from a variety of scientific and technical disciplines. RNA science has progressed enormously in...
2 nd edition: Taylor & Francis Group, 2006. — 305 p. — ISBN: 0-203-00267-9. This book contains information obtained from authentic and highly regarded sources. Reprinted material is quoted with permission, and sources are indicated. A wide variety of references are listed. Reasonable efforts have been made to publish reliable data and information, but the author and the...
Wiley, 2014. — 815 p. Meeting the need for an up-to-date and detailed primer on all aspects of the topic, this ready reference reflects the incredible expansion in the application of FRET and its derivative techniques over the past decade, especially in the biological sciences. This wide diversity is equally mirrored in the range of expert contributors. The book itself is...
Springer, 2013. - 485 p. - Biological membranes play a central role in cell structure, shape and functions. However, investigating the membrane bilayer has proved to be difficult due to its highly dynamic and anisotropic structure, which generates steep gradients at the nanometer scale. Due to the decisive impact of recently developed fluorescence-based techniques, tremendous...
Wiley-VCH Verlag, Weinheim,, 2007, 304 p. Knowledge of the atomic structure of biomacromolecules such as proteins, nucleic acids and carbohydrates is indispensable for an understanding their biological function. The sequencing of whole genomes from bacteria to man has provided the possibility to clone and express their gene products, which in most cases are proteins. The new...
2nd Edition. — Wiley-Blackwell, 2008. — 9600 p. — ISBN10: 3527305424, ISBN13: 978-3527305421 16 Volume Set edition This second edition of the Encyclopedia of Molecular Cell Biology and Molecular Medicine covers the molecular and cellular basis of life, disease, and therapy at university and professional researcher level. With its 16 volumes, this is the most comprehensive and...
2nd Edition. — Wiley-Blackwell, 2008. — 9600 p. — ISBN10: 3527305424, ISBN13: 978-3527305421 16 Volume Set edition This second edition of the Encyclopedia of Molecular Cell Biology and Molecular Medicine covers the molecular and cellular basis of life, disease, and therapy at university and professional researcher level. With its 16 volumes, this is the most comprehensive and...
Wiley, 2014. - 883 p. - Based on one of the leading encyclopedic resources in cell and molecular biology worldwide, this two-volume work contains more than 75% new content, not previously published in the Encyclopedia. All the other chapters have been carefully updated. The result is a comprehensive overview of the different functions of the various forms of RNA in living...
Springer, 2020. — 254 p. — (Concepts and Strategies in Plant Sciences). — ISBN: 978-3-030-35771-9. This book summarizes the latest findings on the functions of microRNAs in the regulation of plant development and responses to the surrounding environment. MicroRNAs are an important class of molecules that can be found in diverse groups of organisms, including plants and animals,...
Stockholm: Sweden by Universitetsservice AB. 2010 — 250 p. Mitochondrial form and function in pancreatic β-cells and brown adipocytes Picture on cover: Brown adipocyte stained with the red mitochondrial membrane potential sensitive dye TMRE. In addition a subset of the mitochondrial population is also labeled with photo-convertible GFP. The image was acquired with a Zeiss LSM...
Cambridge University Press, 2014. - 438 p. - Quantum mechanics provides the most accurate microscopic description of the world around us, yet the interface between quantum mechanics and biology is only now being explored. This book uses a combination of experiment and theory to examine areas of biology believed to be strongly influenced by manifestly quantum phenomena. Covering...
Springer, 2007. - 246 p. The book presents a class of new results in molecular biology for which topological methods and ideas are important. These include: the large-scale conformation properties of DNA; computational methods (Monte Carlo) allowing the simulation of large-scale properties of DNA; the tangle model of DNA recombination and other applications of Knot theory;...
Academic Press, 2011. — 451 p. — ISBN: 0123705819, 9780123705815 Structural Biology Using Electrons and X-rays is the perfect book to provide advanced undergraduates or graduate students with an accessible introduction to the two major diffraction-based techniques of structural biology. While concentrating on electron cryo-microscopy with image analysis, it also includes X-ray...
CRC Press, 2003. — 434 p. — (Methods in Visualization) — ISBN: 9780849300417 Although the polymerase chain reaction has revolutionized genetic analysis by amplifying rare nucleic acid sequences, the in situ application is the only method that allows the localization of amplified signal within tissue structure. The applications of in situ polymerase chain reaction have greatly...
CRC Press, 2016. - 347 p. - Thoroughly researched using experimentation and re-examination of all previously published evidence, Molecular and Physiological Mechanisms of Muscle Contraction is a carefully crafted treatise and revision of previous conceptions of muscle contraction. It presents detailed descriptions of new, previously unpublished data and hybrids recent findings...
Taylor & Francis Group, 2005. - 385 p. - Of recent, the structure of the complement system has received considerable attention, including the publication of several three-dimensional structures of complement proteins. This has led to the need for an authoritative resource to provide a complete overview of the basics, as well as an explanation of the cutting-edge work being...
Springer, 2011. - 416 p. - The concept of ‘biomineralization’ signifies mineralization processes that take place in close association with organic molecules or matrices. The awareness that mineral formation can be guided by organic molecules notably contributed to the understanding of the formation of the inorganic skeletons of living organisms. Modern electron microscopic and...
Royal Society of Chemistry, 2008. - 289 p. - This unique book covers all the modern approaches and the many advances experienced in the field during the last 10 years. There is much emphasis on computational methods and studies of protein aggregation which have really flourished in the last decade. It includes chapters in the areas that have witnessed major developments and...
2nd Edition. — ExLi4EvA, 2016. — 183 p. — ISBN: 9535105647 This book illustrates methods of DNA sequencing and its application in plant, animal and medical sciences. This book is intended to serve as an important resource and review to the researchers in the field of DNA sequencing. The book has two distinct sections. The one includes 2 chapters devoted to the DNA sequencing...
Duke University Press, 2015. - 333 p. What are living bodies made of? Protein modelers tell us that our cells are composed of millions of proteins, intricately folded molecular structures on the scale of nanoparticles. Proteins twist and wriggle as they carry out the activities that keep cells alive. Figuring out how to make these unruly substances visible, tangible, and...
Springer Singapore, 2019. — 272 p. — ISBN 978-981-13-2200-6, 978-981-13-2199-3, ASIN B07FNF4QV6. This book presents a new emerging concept of "Integrative Structural Biology". It covers current trends of the molecular and cellular structural biology, providing new methods to observe, validate, and keep the structural models of the large cellular machines with recent scientific...
Springer Singapore, 2019. — 272 p. — ISBN 978-981-13-2200-6, 978-981-13-2199-3, ASIN B07FNF4QV6. This book presents a new emerging concept of "Integrative Structural Biology". It covers current trends of the molecular and cellular structural biology, providing new methods to observe, validate, and keep the structural models of the large cellular machines with recent scientific...
Advances in Chemical Physics, vol. 29, An Interscience Publication, John Wiley & Sons, Inc., 1975, - 388 p. Many of the papers published in this volume were presented at an European Molecular Biology Organization (EMBO) conference held in Brussels, November 22-24, 1972. The papers cover biological control systems, biological physic, and biological chemistry.
Springer New York, 2010. — 505 p. In the field of molecular evolution, inferences about past evolutionary events are made using molecular data from currently living species. With the availability of genomic data from multiple related species, molecular evolution has become one of the most active and fastest growing fields of study in genomics and bioinformatics. Most studies in...
3rd edition. — CRC Press, 2013. — 453 p. — ISBN: 9781138198586 PCR’s simplicity as a molecular technique is, in some ways, responsible for the huge amount of innovation that surrounds it, as researchers continually think of new ways to tweak, adapt, and re-formulate concepts and applications. PCR Technology: Current Innovations, Third Edition is a collection of novel methods,...
CRC Press, 2009. - 465 p. - It can be argued that the dawn of the 21st century has emerged as the age focused on molecular biology, which includes all the regulatory mechanisms that make cellular biochemical reaction pathways stable and life possible. For biomedical engineers, this concept is essential to their chosen profession. Introduction to Molecular Biology, Genomics, and...
Springer, 2019. — 318 p. — (Advances in Experimental Medicine and Biology 1203). — ISBN: 978-3-030-31433-0. The book provides an overview on the different aspects of gene regulation from an mRNA centric viewpoint, including how mRNA is assembled and self-assembles in a complex consisting of RNA and proteins, and how its ability to be translated at the right time and space...
Springer, 2018. — 232 p. — (Integrated Analytical Systems). — ISBN: 978-3-319-64745-6. This book presents an overview of fundamental aspects of surface-based biosensors and techniques for enhancing their detection sensitivity and speed. It focuses on rapid detection using miniaturized sensors and describes the physical principles of nanoscale transducers, surface modifications,...
Springer, 2012. — 437 p. Channels and transporters are multi-functional proteins that mediate substrate transport and signal transmission and simultaneously act as regulators for other proteins and biosensors for environmental materials. Patch clamping is an epoch-making technique that allows researchers to perform real-time measurements of electrogenic channel/transporter...
Springer, 2018. — 234 p. This book presents cutting-edge research on the use of physical and mathematical formalisms to model and quantitatively analyze biological phenomena ranging from microscopic to macroscopic systems. The systems discussed in this compilation cover protein folding pathways, gene regulation in prostate cancer, quorum sensing in bacteria to mathematical and...
Wiley, 2014. — 567 p. New insights into the evolution and nature of proteins Exploring several distinct approaches, this book describes the methods for comparing protein sequences and protein structures in order to identify homologous relationships and classify proteins and protein domains into evolutionary families. Readers will discover the common features as well as the key...
Wiley-Blackwell, 2017. — 341 p. — ISBN: 9781119165026. This book addresses the difficulties experienced by wet lab researchers with the statistical analysis of molecular biology related data. The authors explain how to use R and Bioconductor for the analysis of experimental data in the field of molecular biology. The content is based upon two university courses for...
Wiley, 2009. - 311 p. - Protein Targeting with Small Molecules: Chemical Biology Techniques and Applications takes readers beyond the use of chemical biology in basic research, providing a highly relevant look at techniques that can address the challenges of biology and drug design and development. This indispensable bench companion features up-to-date coverage of advances in...
Science Squared Ltd, 2012. — 39 p. This short eBook provides 10 such nuggets, neatly contained in one place. From How SDS-PAGE works to the chemical reason why enzymes have optimal temperatures we hope that there will be something in here that will enlighten and entertain even the most experienced scientist. What's happening under the hood of your kits and protocols What's...
Taylor & Francis Group, 2014. - 470 p. - As a result of their unique physical properties, biological membrane mimetics, such as liposomes, are used in a broad range of scientific and technological applications. Liposomes, Lipid Bilayers and Model Membranes: From Basic Research to Application describes state-of-the-art research and future directions in the field of membranes,...
Academic Press, 2020. — 497 p. — ISBN: 978-0-12-814855-6. This book reviews the mathematical and physical foundations of molecular structural biology. Based on these fundamental concepts, it then describes molecular structure and explains basic genetic mechanisms. Given the increasingly interdisciplinary nature of research, early career researchers and those shifting into an...
Facts on File, 2004. — 208 p. Understanding the cell is the key to grasping the significant potential and technological developments of the new biology. Gene therapy, animal cloning, and stem cell therapy are possible now only because of the great advances in our knowledge of cell biology, which modern technology has allowed scientists to make. As researchers are able to...
McGraw-Hill, 1998. — 251 p. Introduction to Molecular Biology focuses on molecular biology concepts and less on expanded data and themes. It presents a solid framework of concepts to better prepare students for more detailed courses in molecular biology and genetics. Written for science majors, this introductory, one-semester molecular biology text is designed for a...
CRC Press, 2019. - 263 p. With the advances in the field of molecular biology, new tools make it possible to conduct in-depth studies in food microbial communities from a molecular perspective. Information from genomic, transcriptomic, proteomic and metabolomic studies can be integrated through bioinformatic applications, thereby improving our understanding of the interactions...
Medical Information Science Reference, 2008 — 460 p. As science continues to advance, researchers are continually gaining new insights into the way living beings behave and function, and into the composition of the smallest molecules. Most of these biological processes have been imitated by many scientific disciplines with the purpose of trying to solve different problems, one...
Taylor & Francis Group, 2011. — 514 p. This book presents an overview of the current state of research in both synchrotron radiation and structural proteomics from different laboratories worldwide. The book presents recent research results in the most advanced methods of synchrotron radiation analysis, protein micro- and nano crystallography, X-ray scattering and X-ray optics,...
Academic Press, 2000. — 681 p. Since the first gap junction protein (connexin) was cloned over a decade ago, more than a dozen connexin genes have been cloned. Consequently, a wealth of information on the molecular basis of gap junctional communication has been accumulated. This book pays tribute to this exciting era in the history of cell communication research by documenting...
New Science Press, 2004. - 184 p. The genomics revolution is providing gene sequences in exponentially increasing numbers. Converting this sequence information into functional information for the gene products coded by these sequences is the challenge for post-genomic biology. The first step in this process will often be the interpretation of a protein sequence in terms of the...
Wiley-VCH Verlag GmbH & Co., 2015. — 592 p. The layer-by-layer (LbL) deposition technique is a versatile approach for preparing nanoscale multimaterial films: the fabrication of multicomposite films by the LbL procedure allows the combination of literally hundreds of different materials with nanometer thickness in a single device to obtain novel or superior performance. In the...
The Royal Society of Chemistry, Cambridge, UK, 2011. — 373 p. — ISBN: 1849730091 RSC Biomolecular Sciences, №22 The specific recognition of one molecule by another lies at the heart of all biomolecular processes. It is difficult to think of any area of biology where such interactions are not central, providing the super-structures that define cellular systems, selectivity that...
Wiley, 2010. - 495 p. - A guide to using molecular biology and immunological methods for the analysis of food. Many of the analytical problems that food chemists face in the lab cannot be solved by chemistry alone, and so analytical chemists are turning to molecular biology and immunology for alternative approaches. Molecular Biological and Immunological Techniques and...
CRC Press, 2010. — 508 p. This book covers the structure and classification of adhesion molecules in relation to signaling pathways and gene expression. It discusses immunohistochemical localization, neutrophil migration, and junctional, functional, and inflammatory adhesion molecules in pathologies such as leukocyte decompression sickness and ischemia reperfusion injury....
7th ed. ,2006 - 667 p. BLACKWELL PUBLISHING. Main Street, Malden, MA 02148-5020, USA. Garsington Road, Oxford OX4 2DQ, UK. Swanston Street, Carlton, Victoria 3053, Australia. The book describes the main technologies used in molecular genetics, genetic engineering and bioinformatics. Gene manipulation in the post-genomics era. Fundamental Techniques of Gene. Manipulation. Basic...
Apple Academic Press, 2018. - 335 p. This new book, Molecular Biology: Different Facets, provides a comprehensive description of the basic tenets of molecular biology, from mechanisms to its elaborate role in gene regulation. The initial sections cover the history of genetics and molecular biology. The book then goes on to highlight the significance of molecular approaches for...
Oxford University Press, 2012. — 256 p. Seventy years ago, Erwin Schrödinger posed a simple, yet profound, question: 'What is life?'. How could the very existence of such extraordinary chemical systems be understood? This problem has puzzled biologists and physical scientists both before, and ever since. Living things are hugely complex and have unique properties, such as...
Oxford University Press, 2012. — 256 p. Seventy years ago, Erwin Schrödinger posed a simple, yet profound, question: 'What is life?'. How could the very existence of such extraordinary chemical systems be understood? This problem has puzzled biologists and physical scientists both before, and ever since. Living things are hugely complex and have unique properties, such as...
Oxford University Press, 2012. — 256 p. Seventy years ago, Erwin Schrödinger posed a simple, yet profound, question: 'What is life?'. How could the very existence of such extraordinary chemical systems be understood? This problem has puzzled biologists and physical scientists both before, and ever since. Living things are hugely complex and have unique properties, such as...
Wiley, 1978. — 459 p. Basic theory of intermolecular forces: Applications to small molecules Elaboration of approximate formulas for the interactions between large molecules Studies of biomolecular interactions The fine structure of hydrogen bond
Springer, 2008. - 254 p. - This book integrates concepts and methods from physics, biology, biochemistry and physical chemistry into a standalone, unitary text of biophysics that aims to provide a quantitative description of structures and processes occuring in living matter. The book introduces graduate physics students and physicists interested in biophysics research to...
Wiley-Blackwell, 2000. — 202 p. — ISBN10: 0632043792, 13 978-0632043798. The 11th Hour Series is designed to be used when a textbook doesn''t make sense, when the course content is tough, or when you just want a better grade in the course. The authors cut through the fluff, get to what you need to know, and then help you understand it. Clinical correlations or everyday...
Laboratory manuals. — Humana Press, 2001. — 264 p. (Methods In Molecular Biology, vol. 170) Microarray technology provides a highly sensitive and precise technique for obtaining information from biological samples, with the added advantage that it can handle a large number of samples simultaneously that may be analyzed rapidly. Researchers are applying microarray technology to...
5th Ed. — Pearson Education, 2017. — 571 p. — (Practical Skills). — ISBN10: 1292100737, 13 978-1292100739. If you are studying the biomolecular sciences - including biochemistry, biomedical sciences, biotechnology, genetics, microbiology and molecular biology - then this book will be an indispensable companion throughout the whole of your degree programme. It provides effective...
4th Edition. — Pearson Education, 2013. — 571 p. If you are a studying within the biomolecular sciences (including biochemistry, biomedical sciences, biotechnology, genetics, microbiology and molecular biology) then this book will be an indispensable companion throughout the whole of your degree programme. It provides effective support for the development of the laboratory and...
Springer, 2010. — 269 p. — ISBN10: 3642100813, 13 978-3642100819. This comprehensive text provides an overview of the state of art of alginate material properties, genetics and the molecular mechanisms underlying alginate biosynthesis as well as applications of tailor-made alginates in medicine, food and biotechnology.
Caister Academic Press, 2014. - 515 p. - Membranes are pivotal components of life, acting as formidable insulators that demarcate a living cell; generate energy in the form of ion gradients; transport ions, proteins, nucleic acids, nutrients, and metabolites; and provide transduction systems to sense the environment and to communicate with other cells. Membranes also provide...
2nd Edition. — Humana Press, 2009. — 268 p. Through the study and application of bioluminescence, scientists have painstakingly harnessed a powerful tool that enables us to seek a deeper understanding of the complex mechanisms underpinning so many vital biologic systems. In this fully revised and updated second edition of Bioluminescence: Methods and Protocols, expert...
Intech, 2013. — 329 p. As biosensors comprise a prospective alternative to traditional chemical analyses, enabling fast on- and in-line measurements with sufficient selectivity, the field is expanding rapidly and is offering new ideas and developments every day. This book aims to cover the present state of the art in the biosensor technology and introduce the general aspects of...
Wiley, 2016. — 267 p. This book is geared to every student in biology, pharmacy and medicine who needs to become familiar with receptor mediated signaling. The text starts with explaining some basics in membrane biochemistry, hormone biology and the concept of receptor based signaling as the main form of communication between cells and of cells with the environment. It goes on...
Wiley, 2011. - 443 p. - Designed as a research-level guide to current strategies and methods of membrane protein production on the small to intermediate scale, this practice-oriented book provides detailed, step-by-step laboratory protocols as well as an explanation of the principles behind each method, together with a discussion of its relative advantages and disadvantages....
Springer, 2017. — 277 p. — ISBN: 978-981-10-4498-4. This book highlights the current state of the art in single cell analysis, an area that involves many fields of science – from clinical hematology, functional analysis and drug screening, to platelet and microparticle analysis, marine biology and fundamental cancer research. This book brings together an eclectic group of...
Springer-Verlag, 2011. - 452 p. - The ribosome is a macromolecular machine that synthesizes proteins with a high degree of speed and accuracy. Our present understanding of its structure, function and dynamics is the result of six decades of research. This book collects over 40 articles based on the talks presented at the 2010 Ribosome Meeting, held in Orvieto, Italy, covering...
Momentum Press, 2018. — 134 p. Understanding the molecular underpinnings of life is a task requiring insight from multiple disciplines. In that likeness, biologists have moved toward a systemic approach drawing from the expertise of computational scientists, chemists, engineers, and mathematicians. This collaborative approach requires translation of biological semantics into...
New York: Springer, 2016. — 469 p. Calcium entry pathways in non-excitable cells presents a concise synthesis of thoughtfully selected topics covering from the different calcium entry mechanisms in non-excitable cells to the cellular microdomains and organelles regulating the calcium entry process. Particular attention is given to the fascinating group of ion channels involved...
Springer, 2012. - 214 p. - This book fills in a gap in the NO literature. Recent progress in the field of NO-biology shows that NO is generated within distinct cell compartments, including specific plasma membrane regions, mitochondria, chloroplasts, peroxisomes, the Golgi-complex and intracellular membrane systems. NO synthesis plays specific roles in these compartments and,...
New York , Basel, USA: Marcel Dekker, Inc., 2003. — 656 p. — (Surfactant Science Series 111). — ISBN: 0824708997. This text examines films of biomolecules that can provide solid surfaces for catalyzing enzyme reactions, serve in biosensors and as biorecognition elements, mediate nanoparticle formation, and provide a basis for fundamental studies and applications in biomedicine...
Springer, 2018. - 126 p. In this book, the molecular recognition of DNA using small molecules is discussed, with a study of the photochemistry of BrU-labeled DNA. The purposes of the study were to develop small molecules for regenerative medicine, to develop a method to detect the recognition site of small molecules, and to detect the most important biological phenomena using...
ITexLi, 2016. — 183 p. — ISBN: 9535127969 This volume is a collection of chapters for both novice and experienced scientists and technologists aiming to address obtaining an optimized real-time PCR result, simultaneous processing of a large number of samples and assays, performing PCR and RT-PCR on cell lysate without extraction of DNA or RNA, detecting false-positive PCR...
Academic Press, 2017. - 310 p. - Volume 329 of International Review of Cell and Molecular Biology Early Stage Protein Misfolding and Amyloid Aggregation, Volume 329, the latest in the International Review of Cell and Molecular Biology series presents comprehensive reviews and current advances in cell and molecular biology, including articles that address the structure and...
ExLi4EvA (ITexLi), 2016. – 188 p. – ISBN: 9535122614 This book gives a comprehensive overview of recent advances in Retrovirology, as well as general concepts of molecular biology of retroviral infections, immunopathology, diagnosis, and prevention, to current clinical recommendations in management of retroviruses, including endogenous retroviruses, highlighting the ongoing...
Hardcover: 484 p. Publisher: Wiley-Liss; 2 edition (November 27, 2007) Language: English ISBN10: 9780470040737, ISBN13: 978-0470040737 This book is the eagerly awaited second edition of the best-selling Mitochondria, a book widely acknowledged as the first modern, truly comprehensive authored work on the important, scientifically fundamental topic of the cellular organelles...
The Johns Hopkins University Press, 1993. - 715 p. ISBN: 0801846730 In the first edition of Genetics and Molecular Biology, renowned researcher and award-winning teacher Robert Schleif produced a unique and stimulating text that was a notable departure from the standard compendia of facts and observations. Schleif's strategy was to present the underlying fundamental concepts of...
Wiley-VCH, 2003. — 605 p. — ISBN: 3-527-30594-7. The latest knowledge on molecular motors is vital for the understanding of a wide range of biological and medical topics: cell motility, organelle movement, virus transport, developmental asymmetry, myopathies, and sensory defects are all related to the function or malfunction of these minute molecular machines. Since there is a...
Wiley, 2013. — 672 p Fusion proteins belong to the most lucrative biotech drugs — with Enbrel being one of the best-selling biologics worldwide. Enbrel represents a milestone of modern therapies just as Humulin, the first therapeutic recombinant protein for human use, approved by the Fda in 1982 and Orthoclone the first monoclonal antibody reaching the market in 1986. These...
Wiley, 2012. - 583 p. - Sheds new light on intrinsically disordered proteins and peptides, including their role in neurodegenerative diseases. With the discovery of intrinsically disordered proteins and peptides (IDPs), researchers realized that proteins do not necessarily adopt a well defined secondary and tertiary structure in order to perform biological functions. In fact,...
Springer, 2013. — 176 p. — Advances in Biochemical Engineering/Biotechnology, v.133. Integration in Bioanalysis: Technologies for Point-of-Care Testing, by Frank F. Bier, Soeren Schumacher Future of Medicine: Models in Predictive Diagnostics and Personalized Medicine, by Babette Regierer, Valeria Zazzu, Ralf Sudbrak, Alexander Kühn and Hans Lehrach A Highly Versatile Microscope...
Wiley, 2015. — 267 p. Built on a decade of experience with novel molecular diagnostics, this practice-oriented guide shows how to cope with validation issues during all stages of biomarker development, from the first clinical studies to the eventual commercialization of a new diagnostic test.
InTech. 2011. 708 p.v The study of DNA advanced human knowledge in a way comparable to the major theories in physics, surpassed only by discoveries such as fire or the number zero. However, it also created conceptual shortcuts, beliefs and misunderstandings that obscure the natural phenomena, hindering its better understanding. The deep conviction that no human knowledge is...
2nd Edition. — ExLi4EvA, 2016. — 707 p. — ISBN: 9533075937 This book offers to readers current trends in the field of DNA replication. The study of DNA advanced human knowledge in a way comparable to the major theories in physics, surpassed only by discoveries such as fire or the number zero. The deep conviction that no human knowledge is perfect, but only perfectible, should...
The Royal Society of Chemistry, 2014. - 631 p. - The complexity and heterogeneity of biological systems has posed an immense challenge in recent years. An increasingly important tool for obtaining molecular and atomic scale information on a range of large biological molecules and cellular components is solid-state NMR. This technique can address fascinating problems in...
Nova Science Publishers, 2011. - 176 p. - This book presents and discusses topical research in the study of DNA, genetics and cell biology. Topics discussed include DNA damage related to exposure to oil spills; mutation detection in TP53 gene; DNA and protein sequence analysis; the role of effectors on hypoxia due to nitric oxide production in human alveolar epithelial cells...
Academic Press, 2019. — 451 p. — ISBN: 978-0-12-802823-0. This book describes the fundamentals of molecular biology in a clear, concise manner to aid in the comprehension of this complex subject. Each technique described in this book is explained within its conceptual framework to enhance understanding. The targeted approach covers the principles of molecular biology including...
CRC Press, 2000. — 384 p. — ISBN: 0849309425 Calcium signalling occupies a preeminent position in the signal transduction system of the cell by virtue of its participation in a wide range of physiological functions together with the biological events associated with genetic expression, cell proliferation and apoptosis, as well as cell differentiation and morphogenesis.
World Scientific Publishing, 2006. — 500 p. This book, written by a distinguished scientist in the field, provides a comprehensive overview of the biochemical aspects of all luminous organisms currently known. It is the first and only book that provides chemical information on all known bioluminescence systems, in a single volume. Some 35 different types of bioluminescence...
Elsevier, 2010. - 367 p. (Methods in Cell Biology, Volume 98) - In recent years new discoveries have made this an exciting and important field of research. This comprehensive volume presents comprehensive chapters and detailed background information for researchers working with in the field of Nuclear Mechanics and Genome Regulation. * Both classic and state-of-the-art methods...
Springer, 2008. - 677 p. - Comprehensive theoretical and experimental analysis of UV-radiation and low energy electron induced phenomena in nucleic acid bases (NABs) and base assemblies are presented in this book. NABs are highly photostable; the absorbed energy is dissipated in the form of ultrafast nonradiative decay. This book highlights the possible mechanisms of these...
Springer, 2012. - 386 p. - The Metal Ions in Life Sciences series links coordination chemistry and biochemistry in their widest sense and thus increases our understanding of the relationship between the chemistry of metals and life processes. The series reflects the interdisciplinary nature of Biological Inorganic Chemistry and coordinates the efforts of scientists in fields...
Springer, 2017. — 251 p. This book provides essential information on improving protein folding/stability, which is a result of the balance between the intra-molecular interactions of protein functional groups and their interactions with the solvent environment. The protein folding solvent environment mainly consists of salts, small molecule compounds, metabolites, molecular...
Springer, 2016. - 132 p. This thesis offers readers a comprehensive introduction to amyloid proteins and the computational methods used with them. Katrine Skeby critically assesses and compares both the literature and the experiments performed by other researchers, which further elevates the quality and relevance of her own work. Amyloid proteins are highly complex, and this...
Springer, 1988. - 205 p. Crystalline surface layers (S-layers) represent an almost universal feature of archaebacterial cell envelopes and can be found in gram-positive and gram-negative eubacterial species from nearly all phylogenetic branches. S-layers consist of a single protein- or glycoprotein species and thus can be considered as one of the most primitive membrane...
Academic Press, 1996. - 245 p. Crystalline Bacterial Cell Surface Proteins assembles information on the understanding of the occurrence, structure, chemistry, genetics, assembly, function, and application potential of S-layers. The chapters are designed to stand independent of each other and provide a complete survey of the different topics in S-layer research. This book is...
Cold Spring Harbor Laboratory Press, 2000. — 1020 p. Preface/Front Matter. Origins and Principles of Translational Control. The Pathway and Mechanism of Initiation of Protein Synthesis. The Protein Biosynthesis, Elongation Cycle. A Comparative View of Initiation Site Selection Mechanisms. Mechanism and Regulation of Initiator Methionyl-tRNA Binding to Ribosomes. Regulation of...
CRC Press, 2006. — 191 p. Prion-related diseases, known as transmissible spongiform encephalopathies (TSEs), are infectious, fatal neurodegenerative disorders for which there is no cure, treatment, nor even a means for early diagnosis. The horrific advent of Mad Cow Disease -- transmitted to humans through eating meat from steers sickened by bovine spongiform encephalopathy...
Springer, 2013. - 308 p. In recent years, a number of groundbreaking structural and mechanistic studies deepened our understanding of helicase mechanisms and established new approaches for their analyses. Many fundamental mechanistic questions ranging from the mechanism of force generation, mechanochemical coupling to distinct mechanisms by which the same enzyme translocates on...
McGraw-Hill, 2003. — 129 p. The book is a pared-down, simplified, and tightly focused review of the topic. With an emphasis on clarity and brevity, it features a streamlined and updated format and the absolute essence of the subject, presented in a concise and readily understandable form. Graphic elements such as sidebars, reader-alert icons, and boxed highlights stress...
2nd Edition. - Wiley, 1989. - 534 p. - In response to the expansion of knowledge in biochemistry and molecular biology, the Second Edition of this reference has been completely revised and updated, with approximately 16,000 new entries. Names of specific compounds and other substances have been substantially enlarged, and definitions have been expanded for clarity and...
Cambridge University Press, 2004. — 288 p. — ISBN10: 052161211X, ISBN13: 978-0521612111. The biology of birds is diverse and frequently differs significantly from that of other vertebrates. Many birds migrate or fly at high altitudes, while egg-laying and feather production places high demands on nutrient uptake and storage. This book is the only comprehensive and up-to-date...
Springer, 2015. - 380 p. - The book focuses on the aqueous interface of biomolecules, a vital yet overlooked area of biophysical research. Most biological phenomena cannot be fully understood at the molecular level without considering interfacial behavior. The author presents conceptual advances in molecular biophysics that herald the advent of a new discipline, epistructural...
Elsevier, 2013. — 364 p. An Introduction to Biological Membranes: From Bilayers to Rafts covers many aspects of membrane structure/function that bridges membrane biophysics and cell biology. Offering cohesive, foundational information, this publication is valuable for advanced undergraduate students, graduate students and membranologists who seek a broad overview of membrane...
Springer, 2013. — 219 p. G protein coupled receptors (GPCRs) comprise an important protein family, which is involved in signal transduction in the cell. Besides that a large number of drugs, available on market, address GPCRs. For an efficient and improved development of appropriate drugs, molecular modeling of GPCRs is – in order to understand the ligand-receptor interactions...
Academic Press, 2008. - 613 p. - This new edition of Fluorescent Proteins presents current applications of autofluorescent proteins in cell and molecular biology authored by researchers from many of the key laboratories in the field. Starting from a current review of the broad palette of fluorescent proteins available, several chapters focus on key autofluorescent protein...
CRC, 2017. — 364 p. — ISBN: 978-1-4665-6550-0. Advances in sequencing technology have allowed scientists to study the human genome in greater depth and on a larger scale than ever before – as many as hundreds of millions of short reads in the course of a few days. But what are the best ways to deal with this flood of data? Algorithms for Next-Generation Sequencing is an...
Becom Co., Ltd., 2009. - 229 p. Rin and Ami have been skipping molecular biology class all semester, and Professor Moro has had enough-he's sentencing them to summer school on his private island. But they're in store for a special lesson. Using Dr. Moro's virtual reality machine to travel inside the human body, they'll get a close-up look at the fascinating world of molecular...
Springer, 2015. - 1521 p. - Glycans (carbohydrate oligomers) are the so-called building blocks of carbohydrates, nucleic acids, proteins and lipids and play major roles in many biological phenomena as well as in various pathophysiological processes. However, this area of glycoscience has been neglected from the research community because glycan structures are very complex and...
3th Edition. Springer, 2009 - 758 p. The Handbook is intended to be a service to the neuroscience community , to help in finding available and useful information, to point out gaps in our knowledge, and to encourage continued studies. It represents the valuable contributions of the many authors of the chapters and the guidance of the editors and most important, it represents...
2nd Edition. — Academic Press, 2018. — 841 p. — ISBN: 978-0-12-804182-6. This book, Second Edition, is aimed at students of bone biology and genetics and includes general introductory chapters on bone biology and genetics. More specific disease orientated chapters comprehensively summarize the clinical, genetic, molecular, animal model, molecular pathology, diagnostic,...
Springer, 2013. — 385 p. Attachment of dissimilar materials in engineering and surgical practice is a perennial challenge. Bimaterial attachment sites are common locations for injury, repeated injury, and mechanical failure. Nature presents several highly effective solutions to the challenge of bimaterial attachment that differ from those found in engineering practice....
Springer, 2014. — 204 p. — (Advances in Biochemical Engineering/Biotechnology. Volume 144) — ISBN: 9783662433843 This book review series presents current trends in modern biotechnology. The aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical...
Springer-Verlag, Berlin, Heidelberg, 2014. — 224 p. — (Advances in Biochemical Engineering/Biotechnology. Volume 145) — ISBN: 9783662436189 This book review series presents current trends in modern biotechnology. The aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology,...
Springer International Publishing, Switzerland, 2016. — 202 p. — (Advances in Biochemical Engineering/Biotechnology. Volume 154) — ISBN10: 3319274058 This book review series presents current trends in modern biotechnology. The aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required from chemistry, biochemistry,...
Academic Press, 2019. — 248 p. — ISBN: 978-0-12-813335-4. This book thoroughly details key psychological factors to consider while implementing genome sequencing in clinical practice, taking into account the subtleties of genetic risk assessment, patient consent and best practices for sharing genomic findings. Chapter contributions from leading international researchers and...
Springer, 2015. — 42 p. This book offers low-cost and rapid molecular assays for the characterization of mutant plant germplasm. Detailed protocols are provided for the desiccation of plant tissues; the extraction of high-quality DNA for downstream applications; the extraction of single-strand-specific nucleases for single nucleotide polymorphism; and small insertion/deletion...
Springer, 2016. - 165 p. This thesis presents a method for reliably and robustly producing samples of amyloid-β (Aβ) by capturing them at various stages of aggregation, as well as the results of subsequent imaging with various atomic force microscopy (AFM) methods, all of which add value to the data gathered by collecting information on the peptide’s nanomechanical, elastic,...
ITexLi (ExLi4EvA), 2016. – 365 p. – ISBN: 9535124161; 9535124153 This book overviews the role of the extracellular matrix (ECM) in different tissues and organs of the human body. The extracellular matrix (ECM) is an ensemble of non-cellular components present within all tissues and organs of the human body. The ECM provides structural support for scaffolding cellular...
Wiley, 2007. - 769 p. - This book provides an integrated treatment of the structure and function of nucleic acids, proteins, and glycans, including thorough coverage of relevant computational biochemistry. The text begins with an introduction to the biomacromolecules, followed by discussion of methods of isolation and purification, physiochemical and biochemical properties, and...
Springer, 2019. — 216 p. — ISBN: 9811381768. This book examines the utility of genome-wide association studies (GWAS) in the era of next-generation sequencing and big data, identifies limitations and potential means of overcoming them, and looks to the future of GWAS and what may lay beyond. GWAS are among the most powerful tools for elucidating the genetic aspects of human and...
Scientific Computing Ltd., 2003. — 161 p. — ISBN: 952-9821-89-1. This is the first edition of the DNA microarray data analysis guidebook. Although invented in the mid-90s, DNA microarrays are still novelties as biomedical research tools. DNA microarrays generate large amounts of numerical data, which should be analyzed effectively. In this book, we hope to offer a broad view of...
Springer, 2016. — 171 p. — ISBN: 978-3-319-34146-0. This timely volume explores the use of CRISPR-Cas9 for genome editing, presenting cutting-edge techniques and their applications in treatment of disease. The chapters describe latest methods such as use of targetable nucleases, investigation of the non-coding genome, mouse genome editing, increasing of knock-in efficiency in...
3th edition. —Taylor & Francis, 2005. — 370 p. — (Instant Notes). — ISBN 0–203–96732–1 The new edition of Instant Notes in Molecular Biology has been revised and updated to include information on micro RNAs, RNA inhibition, functional genomics, proteomics, imaging, stem cells and bioinformatics. Written in an accessible style, the book will be a highly useful tool for studying...
Academic Press, 2019. — 282 p. — ISBN: 978-0-12-814685-9. This book is the first book to compile information about helicases from many different organisms in a single volume. Research in the helicase field has been going on for a long time now, but the completion of so many genomes of these ubiquitous enzymes has made it difficult to keep up with new discoveries. As the huge...
BIOS Scientific Publishers, 1998. - 512 p. - This book emphasises the unifying principles and mechanisms of molecular biology, with frequent use of tables and boxes to summarise experimental data and gene and protein functions. How to use this book Biological Heredity and Variation The Cell Cycle Chromatin Chromosome Mutation Chromosome Structure and Function Development,...
Elsevier, 2011. - 377 p. - The growing area of peptide and protein therapeutics research is of paramount importance to medical application and advancement. A needed reference for entry level researchers and researchers working in interdisciplinary / collaborative projects, Peptide and Protein Delivery addresses the current and emerging routes for delivery of therapeutics....
Academic Press, 2018. — 244 p. The Evolution of Molecular Biology: The Search for the Secrets of Life provides the historical knowledge behind techniques founded in molecular biology, also presenting an appreciation of how, and by whom, these discoveries were made. It deals with the evolution of intellectual concepts in the context of active research in an approachable language...
Humana Press, 2012. - 644 p. - Through many recent remarkable developments, perhaps the most significant advancements in the study of transcriptional regulation are the development of genome-wide approaches for measuring gene expression, exemplified by gene chips (chip), and chromatin immunoprecipitation assays (ChIP) for measuring in vivo protein-DNA interactions at any...
Springer, 2018. - 306 p. This book reviews the latest advances in multiple fields of plant biotechnology and the opportunities that plant genetics, genomics and molecular biology have offered for agriculture improvement. Advanced technologies can dramatically enhance our capacity in understanding the molecular basis of traits and utilizing the available resources for...
Springer, 2017. — 218 p. Using a novel approach that combines high temporal resolution of the laser T-jump technique with unique sets of fluorescent probes, this study unveils previously unresolved DNA dynamics during search and recognition by an architectural DNA bending protein and two DNA damage recognition proteins. Many cellular processes involve special proteins that bind...
New York: Humana Press, 2010. — 256 p. Since the introduction of fluorescent calcium indicators and the subsequent development of capacities for real-time monitoring and imaging of calcium movements in the intact cells studied in isolation, in situ and in vivo, the complex and vital calcium signalling system has been illuminated, proving calcium signals to be excellent...
Oxford University Press, 2007 - 384 p. ISBN10: 0198569238; ISBN13: 978-0198569237 Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. However, it is only recently that the necessary sophisticated technology has been developed to begin testing this theory and its consequences. Vijg critically reviews the concept of...
Springer International Publishing Switzerland, 2016. — 159 p. — (Topics in Current Chemistry Collections) — ISBN: 978-3-319-29684-5 The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related...
Birkhauser, 1998. — 287 p. The properties of materials depend on the nature of the macromolecules, small molecules and inorganic components and the interfaces and interactions between them. Polymer chemistry and physics, and inorganic phase structure and density are major factors that influence the performance of materials. In addition, molecular recognition, organic-inorganic...
Wiley, 2005. — 246 p. The past few years have witnessed intense research in this fascinating field as well as many controversial discussions. Now the time is ripe for a comprehensive book covering not only theoretical aspects, but also such mechanistic topics as principles and mechanisms of photoinduced charge injection, transport and trapping in DNA, sequence-dependent DNA...
McGraw-Hill Companies, 2007. - 347 p. - Bridging the gap between biology and engineering, Applied Cell and Molecular Biology for Engineers uses clear, straightforward language to introduce you to the cutting-edge concepts of molecular and cell biology. Written by an international team of engineers and life scientists, this vital tool contains clinical focus boxes and...
Second edition. – Humana Press, 2008. – 1104 p. Recent advances in the biosciences have led to a range of powerful new technologies, particularly nucleic acid, protein and cell-based methodologies. The most recent insights have come to affect how scientists investigate and define cellular processes at the molecular level. Molecular Biomethods Handbook, 2nd Edition expands upon...
Taylor & Francis Group, 2013. - 396 p. - Quantitative methods are revolutionizing modern molecular and cellular biology. Groundbreaking technical advances are fueling the rapid expansion in our ability to observe, as seen in multidisciplinary studies that integrate theory, computation, experimental assays, and the control of microenvironments. Integrating new experimental and...
InTech, 2012. - 443 p. - Coverage of this book includes: Complex formation and dynamics of polymers Dynamics of lipid bilayers, peptides, DNA, RNA, and proteins Complex liquids and plasmas Dynamics of molecules on surfaces Nanofluidics and nanomachines The contents illustrate the rapid progress on molecular dynamics simulations in many fields of science and technology, such as...
Springer, 2016. — 242 p. — ISBN10: 9811016569. — ISBN13: 978-9811016561. This book focuses on cell- and molecule-based biosensors using micro/nano devices as transducers. After providing basic information on micro/nano cell- and molecule-based biosensors, it introduces readers to the basic structures and properties of micro/nano materials and their applications. The topics...
CRC Press LLC, 2016. — 252 p. — ISBN: 9781482217896, 1482217899 A Practical Guide to the Highly Dynamic Area of Massively Parallel Sequencing The development of genome and transcriptome sequencing technologies has led to a paradigm shift in life science research and disease diagnosis and prevention. Scientists are now able to see how human diseases and phenotypic changes are...
Humana Press, 2008. - 349 p. - Within the complex neuronal network of the nervous system, neuron-to-neuron communication occurs mainly through chemical synapses, where the presynaptic nerve terminal releases neurotransmitters that control the function of postsynaptic neurons by acting on postsynaptic receptors. Recent decades have brought groundbreaking new developments and a...
JAI Press, 1993. — 209 p. Advances in Developmental Biology was launched as a series by JAI Press in 1992 with the appearance of Volume 1. This series is inextricably linked to the companion series, Advances in Developmental Biochemistry, that was launched at the same time. As stated in the Preface to Volume 1: “Together the two series will provide annual reviews of research...
5th Ed. — Pearson Education, 2004. — 732 p. As the fifth edition of Molecular Biology of the Gene goes to press, completion of the human genome sequence is no longer news. This was not something that could safely have been anticipated when the first edition appeared in 1965; even when the fourth edition came out in 1987, few if any foresaw how quickly we would move into a world...
7th Edition. — Pearson Education, 2013. — 911 p. Now completely up-to-date with the latest research advances, the Seventh Edition of James D. Watson’s classic book, Molecular Biology of the Gene retains the distinctive character of earlier editions that has made it the most widely used book in molecular biology. Twenty-two concise chapters, co-authored by six highly...
5th Edition. — McGraw-Hill, 2012. — 892 p. Molecular Biology by Robert Weaver, is designed for an introductory course in molecular biology. Molecular Biology 5th edition focuses on the fundamental concepts of molecular biology emphasizing experimentation. In particular author, Rob Weaver, focuses on the study of genes and their activities at the molecular level. Through the...
CRC Press, 2005. — 470 p. — ISBN: 978-0-8493-1488-9 Given the explosive development of new molecular marker techniques over the last decade, newcomers and experts alike in the field of DNA fingerprinting will find an easy-to-follow guide to the multitude of techniques available in DNA Fingerprinting in Plants: Principles, Methods, and Applications, Second Edition. Along with...
Springer, 2012. — 281 p. Michael D. Wendt - Protein-Protein Interactions as Drug Targets; Shaomeng Wang, Yujun Zhao, Denzil Bernard, Angelo Aguilar, Sanjeev Kumar - Targeting the MDM2-p53 Protein-Protein Interaction for New Cancer Therapeutics; Kurt Deshayes, Jeremy Murray, Domagoj Vucic - The Development of Small-Molecule IAP Antagonists for the Treatment of Cancer; John F....
John Wiley & Sons, Inc., 2017. — 442 p. — (Wiley Series on Pharmaceutical Science and Biotechnology: Practices, Applications, and Methods). — ISBN: 1119103061. The first book to offer a blueprint for overcoming the challenges to successfully quantifying biomarkers in living organisms The demand among scientists and clinicians for targeted quantitation experiments has...
Wiley-VCH; 2nd Edition, 2008 - 502 p. ISBN: 978-3-527-31941-1 Short description Still the only concise practical guide, this edition combines the best features of a laboratory manual with a concise reference for successful experimental design. Full coverage of electrophoresis, liquid chromatography, mass spectrometry and further relevant techniques. History Critical points...
Ottawa: National Research Council of Canada, 2001. — 256 p. Publishing information Abstract Résumé The G¹ buildup: getting ready for chromosome replication A checkpoint to pass The S phase: replicating the chromosomes — a daunting task Mitosis and the birth of two new cells Ca²+ and starting the cycle Ca²+ and the G¹–S transition Ca²+ in mitosis Stem cells and cell stacks Ca²+...
Springer, 2013. — 159 p. Bioinformatics, which can be defined as the application of computer science and information technology to the field of biology and medicine, has been rapidly developing over the past few decades. It generates new knowledge as well as the computational tools to create that knowledge. Understanding the basic processes in living organisms is therefore...
Springer, 2015. — 155 p. In his master thesis Thorsten Will proposes the substantial information content of protein complexes involving transcription factors in the context of gene regulatory networks, designs the first computational approaches to predict such complexes as well as their regulatory function and verifies the practicability using data of the well-studied yeast...
Fifth Edition. — 2008, Garland Science. — 588 p. — ISBN10: 0815341105, ISBN13: 978-0815341109 The Problems Book helps students appreciate the ways in which experiments and simple calculations can lead to an understanding of how cells work by introducing the experimental foundation of cell and molecular biology. Each chapter will review key terms, test for understanding basic...
6th Edition. - Garland Science, 2015. - 985 p. - The Problems Book helps students appreciate the ways in which experiments and simple calculations can lead to an understanding of how cells work by introducing the experimental foundation of cell and molecular biology. Each chapter reviews key terms, tests for understanding basic concepts, and poses research-based problems. The...
7th Edition. - Cambridge University Press, 2010. - 762 p. - This best-selling undergraduate textbook provides an introduction to key experimental techniques from across the biosciences. It uniquely integrates the theories and practices that drive the fields of biology and medicine, comprehensively covering both the methods students will encounter in lab classes and those that...
Harvard University Press, 2013. — 197 p. Bioluminescence is everywhere on earth — most of all in the ocean, from angler fish in the depths to the flashing of dinoflagellates at the surface. Here, Thérèse Wilson and Woody Hastings explore the natural history, evolution, and biochemistry of the diverse array of organisms that emit light. While some bacteria, mushrooms, and...
Wiley, 2011. - 437 p. - The intersection of molecular chaperones and neurodegeneration is an intensely studied area because of the potential of manipulating the expression of molecular chaperones to thwart the progression of debilitating diseases. How protein chaperones protect cells from neurodegenerative diseasesIncluding contributions from leading experts, Protein Chaperones...
Springer, 2005. - 208 p. - Contents. M.I. Pividori, S. Alegret: DNA Adsorption on Carbonaceous Materials. F. Luderer, U. Walschus: Immobilization of Oligonucleotides for Biochemical Sensing by Self-Assembled Monolayers: Thiol-Organic Bonding on Gold and Silanization on Silica Surfaces. Y. Okahata, T. Kawasaki: Preparation and Electron Conductivity of DNA-Aligned Cast and LB...
Dordrecht: Springer Science+Business Media, 2012. — 387 p. Genome-Scale Network Modeling Kinetic Modeling of Metabolic Networks Design of Superior Cell Factories Based on Systems Wide Omics Analysis Technologies for Biosystems Engineering Systems Metabolic Engineering of Escherichia coli for Chemicals, Materials, Biofuels, and Pharmaceuticals Systems Metabolic Engineering of...
Axolotl Academic Publishing Company, 2009. — 283 p. Yet another cell and molecular biology book? At the very least, you would think that if I was going to write a textbook, I should write one in an area that really needs one instead of a subject that already has multiple excellent and definitive books. So, why write this book, then? First, it’s a course that I have enjoyed...
CRC Press, 2018. — 332 p. — (Methods in Signal Transduction Series). Autophagy and Signaling is an up-to-date overview of the many signaling pathways regulating autophagy in response to different cellular needs. Discussion includes the status and future directions of autophagy signaling research with respect to different aspects of health and disease. These include the roles of...
Springer, 2013. — 301 p. In recent years, owing to the fast development of a variety of sequencing technologies in the post human genome project era, sequencing analysis of a group of target genes, entire protein coding regions of the human genome, and the whole human genome has become a reality. Next Generation Sequencing (NGS) or Massively Parallel Sequencing (MPS)...
Bookboon, 2010. — 34 p. Genetic origins of amino acids Transcription and translation Amino acid geometries and protein folding Structure-function relationship of proteins Conformational change via epigenetics
Humana Press, 2017. — 248 p. — (Neuromethods). — ISBN10: 1493969447. — ISBN13: 978-1493969449. This volume details methods for the analyses of specific lipid classes and lipidomics analyses of cells such as lymphocytes and oocytes. Lipidomics guides readers through chapters on direct-flow and chromatographic methods (SFC, UHPLC, HPTLC, ion-mobility); derivatization methods for...
CRC Press, 2005. — 230 p. The major aim of this book is to demonstrate the critical techniques utilized in the experiments selected from many significant findings that contribute to our understanding of APP biology. Each technique will be presented in the format of a standard protocol, providing step-by-step instructions for bench scientists carrying out similar studies on APP...
Springer, 2018. - 2018. - 65 p. This book summarizes the emerging experimental evidence on hair-cell mechanotransduction, and covers hair’s cellular structure, biophysical properties, molecular components and functions. Auditory hair cells convert sound-induced vibration into electrical signals. This biological process, mechanotransduction, is what allows us to hear and...
Caister Academic Press, 2014. — 172 p. High-throughput, next generation sequencing (NGS) technologies are capable of producing a huge amount of sequence data in a relatively short time and have revolutionized genome research in recent years. The powerful and flexible nature of NGS has made it an indispensable tool for a broad spectrum of biological sciences, and NGS...
Springer, 2015. - 206 p. - This book serves as an introduction to targeted genome editing, beginning with the background of this rapidly developing field and methods for generation of engineered nucleases. Applications of genome editing tools are then described in detail, in iPS cells and diverse organisms such as mice, rats, marine invertebrates, fish, frogs, and plants. Tools...
Wiley, 2009. - 374 p. - In this first comprehensive resource to cover the application of single molecule techniques to biological measurements, the pioneers in the field show how to both set up and interpret a single molecule experiment. Following an introduction to single molecule measurements and enzymology, the expert authors consider molecular motors and mechanical...
Springer, 2013. — 201 p. — ISBN: 978-3-642-39108-8. Molecular Beacons explains working principle of molecular beacons, discusses their design, synthesis, purification and characterization, explores their thermodynamic and kinetic properties, and more importantly, reviews their in vivo and in vitro applications with the emphasis on the design and modification of molecular...
Springer, 2016. - 71 p. - This book is a passionate account of the scientific breakthroughs that led to the solution of the first protein structures and to the understanding of their function at atomic resolution. The book is divided into self-standing chapters that each deal with a protein or protein family. The subject is presented in a fluid, non-technical style that will...
Springer, 2015. — 399 p. The subject of optogenetics is comprehensively covered in this book, including physical, chemical, and biological topics of light-sensing proteins and their application in biological systems, particularly in neuroscience and medicine and the related opto-electronics. Optogenetics is a new technology that combines genetics and optics. It enables one to...
3rd Edition. - Academic Press, 2016. - 441 p. - The Membranes of Cells, Third Edition, provides a basic guide to biomembranes, connecting researchers to the numerous fields of biology. The new edition offers a complete update of content based on new understandings in the field. Foundational content for graduate students, researchers, professors, and undergraduate students...
3rd Edition. - CRC Press, 2012. - 553 p. - Biological membranes provide the fundamental structure of cells and viruses. Because much of what happens in a cell or in a virus occurs on, in, or across biological membranes, the study of membranes has rapidly permeated the fields of biology, pharmaceutical chemistry, and materials science. The Structure of Biological Membranes,...
2nd Edition. - CRC Press, 2005. - 553 p. - Recent research has provided an abundance of new information on membrane biochemistry. Now more than ever, it is essential to update our current understanding of membrane structure and function to fully appreciate and apply these findings. Completely revised and updated to reflect advances in the field, The Structure of Biological...
Chelsea House, 2012. - 155 p. - The scientist featured in the Times story was J. Craig Venter (1946– ). The article explained that Venter proposed to determine the order, or sequence, of the 6 billion small molecules that make up the DNA, or deoxyribonucleic acid, in the nucleus, or central body, of each human cell. DNA contains the instructions for carrying out cell functions...
Taylor & Francis Group, 2013. - 337 p. - Structural Glycobiology covers the experimental, theoretical, and alternative technologies used in the study of the structural basis for the diverse biological roles of carbohydrates. The book overviews the application of specialized technologies to the study of carbohydrates in biology, reviews relevant and current research in the...
Imperial College Press, 2010. - 401 p. Given the immense progress achieved in elucidating protein protein complex structures and in the field of protein interaction modeling, there is great demand for a book that gives interested researchers/students a comprehensive overview of the field. This book does just that. It focuses on what can be learned about protein protein...
CRC Press, 2010. - 425 p. - With chapter contributions from more than 30 metal biology experts, Cellular and Molecular Biology of Metals explains the role of key divalent metal ions involved in the molecular and cellular biology of various target cell populations. Although it primarily focuses on homeostatic metals, such as nickel, zinc, and chromium, the text also discusses a...
World Scientific, 2006. — 339 p. — ISBN: 9812566457. Series: Science, Engineering, and Biology Informatics (Book 1). This book focuses on the development and application of the latest advanced data mining, machine learning, and visualization techniques for the identification of interesting, significant, and novel patterns in gene expression microarray data. Biomedical...
Springer, 2018. - 389 p. Unlike bacteria and viruses, which are based on DNA and RNA, prions are unique as disease-causing agents since they are misfolded proteins. Prion diseases are called "protein structural conformational” diseases. This monograph is the book on molecular dynamics (MD) simulations nearly for all the known normal prion protein (PrPC) PDB entries in the...
World Scientific Publishing, 2011. - 226 p. - This invaluable book provides the first description of the diverse and fascinating functions of heme in life processes for a broad audience. It begins with an introduction to the intricate chemical properties of heme and the history of early observations of human diseases associated with heme. It then proceeds to describe the...
Wiley-Liss; 1 edition (March 4, 2004) 144 p. ISBN10: 0471453447 Microarray technology provides researchers in the life sciences with a revolutionary tool for measuring gene expression. However, this highly developed process involves multiple steps, from sample selection to data analysis, each susceptible to potentially costly errors. Without sound quality control, experimental...
Springer International Publishing AG, 2018. — 326 p. — (Advances in Biochemical Engineering/Biotechnology 162) — ISBN: 3319553178. This book review series presents current trends in modern biotechnology. The aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics,...
Academic Press, 2019. — 300 p. — ISBN: 978-0-12-814365-0. This book is a resource for the computation of non-coding RNAs. The book covers computational methods for the identification and quantification of non-coding RNAs, including miRNAs, tasiRNAs, phasiRNAs, lariat originated circRNAs and back-spliced circRNAs, the identification of miRNA/siRNA targets, and the identification...
Springer, 2012. - 255 p. - Application of NMR and Molecular Docking in Structure-Based Drug Discovery, by Jaime L. Stark and Robert Powers NMR as a Unique Tool in Assessment and Complex Determination of Weak Protein-Protein Interactions, by Olga Vinogradova and Jun Qin The Use of Residual Dipolar Coupling in Studying Proteins by NMR, by Kang Chen und Nico Tjandra NMR Studies of...
Springer, 2015. — 219 p. — (Advances in Predictive, Preventive and Personalised Medicine) — ISBN: 978-94-017-9213-4 This book focuses on predictive, preventative and personalized medicine (PPPM) and how it is related to the healthcare of rare diseases. Readers will discover how advanced rare diseases healthcare provides an excellent “proof-of-principles” for the personalisation...
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