Pevsner J. Bioinformatics and Functional Gemomics

Wiley, John & Sons, 2003. — 800 p.Introduction to Bioinformatics provides a broad-based introduction to bioinformatics by following three, real-world examples throughout the book: retinol-binding protein, breast cancer, and a calcium binding site C
2. The author emphasizes the use of computational tools and databases to study connections between the structure of proteins and genes to function, development, evolution, and disease. Readers will learn real skills, such as how to analyze genes and proteins, how to make trees using phylogenetic software, how to extract data, or how to identify genes and proteins implicated in diseases.Analyzing DNA, RNA, and Protein Sequences in DatabasesAccess to Sequence Data and Literature Information
Pairwise Sequence Alignment
Basic Local Alignment Search Tool (BLAST)
Advanced BLAST Searching
Genomewide Analysis of RNA and Protein
Bioinformatic Approaches to Gene Expression
Gene Expression: Microarray Data Analysis
Protein Analysis and Proteomics
Protein Structure
Multiple Sequence Alignment
Molecular Phylogeny and Evolution
Genome Analysis
Completed Genomes and the Tree of Life
Completed Genomes: Viruses
Completed Genomes: Bacteria and Archaea
Eukaryotic Genomes: Fungi
Eukaryotic Genomes: From Parasites to Primates
Human Genome
Human Disease
Epilogue
Appendix: GCG for Protein and DNA AnalysisSolutions to Self-Test Quizzes