Springer, 2010. — 194 p.
Chemotherapy has made a dramatic difference to improved survival in patients with cancer. However, not all patients respond and some experience serious side effects. "Pharmacogenetics: Making cancer treatment safer and more effective" is an up to date summary of the exciting new field of how genetic testing can tailor more effective prescription in oncology. It is targeted at oncologists and professionals involved in the treatment of patients with cancer. It provides a core background in genetics and pharmacological principles before providing chapters from acknowledged experts in the field on genetic tests in specific cancer types, including breast, bowel and lung cancer. Clinical cases are used to illustrate the practical application of this knowledge. Chapters on ethics, health economics and the industry aspects of pharmacogenetics set out the challenges and opportunities afforded by this new science.
List of Contributing Authors
Principles of cancer treatment
Clinical pharmacology and anticancer drugs
Pharmacogenetics
Pharmacogenetics in the management of breast cancer
Pharmacogenetics in colorectal cancer
Pharmacogenetics in the management of lung cancer
Pharmacogenetics and cancer treatment in children
Pharmacogenetics in palliative care
Genetic predictors of normal tissue response to radiotherapy
Cancer pharmacogenetics in industry
Ethical issues in pharmacogenetics
Economics of cancer pharmacogenetics
Future directions in cancer pharmacogenetics