Muñoz V. (Ed.) Protein Folding, Misfolding and Aggregation: Classical Themes and Novel Approaches

Royal Society of Chemistry, 2008. - 289 p. - This unique book covers all the modern approaches and the many advances experienced in the field during the last 10 years. There is much emphasis on computational methods and studies of protein aggregation which have really flourished in the last decade. It includes chapters in the areas that have witnessed major developments and written by top experts including: computer simulations of folding, fast folding, single molecule spectroscopy, protein design, aggregation studies (both computational and experimental). Readers will obtain a unique perspective of the problems faced in the biophysical study of protein conformational behavior in aqueous solution and how these problems are being solved with a multidisciplinary approach that combines theory, experiment and computer simulations.Preface: Classical Themes and Novel Approaches in Protein Folding and Aggregation
The Helix as the Simplest Protein Folding Model
Kinetics and Mechanisms of -Helix Formation
Protein Folding Theory
Hydrogen Exchange Experiments
Statistical Differential Scanning Calorimetry
Fast Protein Folding
Single Molecule Spectroscopy in Protein Folding
Computer Simulations of Protein Folding
Protein Design
Protein Misfolding and Amyloid Formation
Computational Studies of Protein Aggregation