Albanna Mohammad Z., Holmes IV James H. Skin Tissue Engineering and Regenerative Medicine

Academic Press, 2016. — 440 p. — ISBN: 978-0-12-801654-1.The skin is the largest human organ system. Loss of skin integrity due to injury or illness results in a substantial physiologic imbalance and ultimately in severe disability or death. From burn victims to surgical scars and plastic surgery, the therapies resulting from skin tissue engineering and regenerative medicine are important to a broad spectrum of patients. Skin Tissue Engineering and Regenerative Medicine provide a translational link for biomedical researchers across fields to understand the inter-disciplinary approaches that expand available therapies for patients and additional research collaboration. This work expands on the primary literature on the state-of-the-art of cell therapies and biomaterials to review the most widely used surgical therapies for specific clinical scenarios.Anatomy, Physiology, Histology, and Immunohistochemistry of Human Skin.
Molecular and Cellular Biology of Wound Healing and Skin Regeneration.
Tissue Processing and Staining for Histological Analyzes.
Clinical Management of Wound Healing and Hypertrophic Scarring.
Process Development and Manufacturing of Human and Animal Acellular Dermal Matrices.
Clinical Applications of Acellular Dermal Matrices in Reconstructive Surgery.
Advances in Acellular Extracellular Matrices (ECM) for Wound Healing.
Natural Biomaterials for Skin Tissue Engineering.
Synthetic Biomaterials for Skin Tissue Engineering.
Hybrid Biomaterials for Skin Tissue Engineering.
Biologic Skin Substitutes.
Wound Healing: A Comprehensive Wound Assessment and Treatment Approach.
Current Innovations for the Treatment of Chronic Wounds.
The Surgical Management of Burn Wounds.
Advances in Isolation and Expansion of Human Cells for Clinical Applications.
Cutaneous Applications of Stem Cells for Skin Tissue Engineering.
Advances in Biopharmaceutical Agents and Growth Factors for Wound Healing and Scarring.
Skin Models for Drug Development and Biopharmaceutical Industry.
Animal Models for Wound Healing.
Human Skin Bioprinting: Trajectory and Advances.
Translational Research of Skin Substitutes and Wound Healing Products.