Mor Gil (ed.) Reproductive Immunology: Basic Concepts

Academic Press, 2021. — 462 p. — (Reproductive Immunology). — ISBN: 978-0-12-818508-7.Reproductive Immunology: Basic Concepts gives a holistic insight into the understanding of the complex interactions between the maternal immune system and the fetal/placental unit necessary for the success of pregnancy. This interaction is critical for the support of the human fetal semiallograft and the protection against infections. The book covers various topics such as B cells, macrophages, and T cells, a discussion on fetal signals and their impact on maternal reproductive cells such as endometrial cells, and mast cells, and the role of fetal Hofbauer cells, the immune regulatory role of glucocorticoids, and many other novel topics within the field of reproductive immunology. Edited and written by experts in the field, this book introduces up-to-date knowledge of the role of the immune system during pregnancy and provides the necessary background to understand pregnancy complications associated with alterations in the functioning of the immune system. The book provides a complete discussion of the immunological aspects of pregnancy and serves as a great tool for research scientists, students, reproductive immunologists, and OBGYNs.The role of the immune system during pregnancy: General concepts.
Presentation and recognition of placental, fetal, and pathogen-derived antigens in human pregnancy.
Uterine macrophages: Essential roles for a successful human pregnancy.
Natural killer cells in reproduction: Before, during and after pregnancy.
To B (e) born: New concepts concerning B cells throughout pregnancy.
Neutrophils: Diverse functions in the endometrium of cycling women and during pregnancy.
Regulatory T cells: Master regulators for the success of pregnancy.
Immunology of the decidua.
Mechanism of glucocorticoid action in immunology — Basic concepts.
The nature of the immune response in microbial-associated and sterile intraamniotic inflammation.
Autoimmunity, regulatory T cells, and pregnancy: Maintaining the balance.
Mucosal immunology of the female reproductive tract and its regulation by female sex hormones.
Toll-like receptors and NOD-like receptors at the implantation site.
Hofbauer cells and placental viral infection.
Gamma/delta T cells in pregnancy.
Placental regulation of immune functions.
TAM receptors in pregnancy.
The epigenetic regulation of the immune system during pregnancy.
Interactions between the epithelial barrier and the microbiota in the reproductive tract.