2nd edition. — Thieme, 2021. — 1570 p. — ISBN: 978-1-62623-532-8.
An increased understanding of the biology and molecular characterization of skull base tumors has led to innovative new approaches. Endoscopic tumor resection, surgical reconstruction, and advances in radiation delivery, chemotherapy, and targeted biologic therapy, have greatly expanded treatment options for patients with these challenging tumors. The updated second edition of Comprehensive Management of Skull Base Tumors by master surgeons Ehab Hanna, Franco DeMonte, and an impressive group of global experts reflects expanded knowledge of skull base tumors and evidence-based advances. This generously illustrated second edition is organized into three sections with 42 chapters. Section I features expanded coverage of endonasal skull base anatomy and surgical principles, as well as radiotherapeutic advances such as proton therapy and stereotactic radiation. Section II is focused on site-specific procedures with emphasis on surgical approaches, and Section III focuses on tumor-specific considerations with emphasis on multidisciplinary treatment approaches. Core topics of this thorough book include pathology, genetics, diagnostic considerations, surgical reconstruction, rehabilitation, chemotherapy, functional outcomes, quality of life issues, neurocognitive assessment, and cerebrovascular management. The most comprehensive resource available today on the management and treatment of skull base tumors, this book is essential reading for neurosurgical and otolaryngology residents. It will also benefit surgeons who specialize in oromaxillofacial, craniofacial, and plastic and reconstructive surgery.
General PrinciplesSurgical Anatomy of the Cranial Base: Transcranial and Endonasal Approaches.
The Pathology of Tumors and Tumorlike Lesions of the Skull Base.
Imaging of Skull Base Neoplasms.
Head, Neck, and Neuro-otologic Assessment of Patients with Skull Base Tumors.
Anesthesia and Intraoperative Monitoring of Patients with Skull Base Tumors.
Endoscopic Endonasal Skull Base Surgery.
Reconstruction of Skull Base Defects.
Radiotherapy for Skull Base Tumors: Principles and Techniques.
Clinical Applications of Radiotherapy for Skull Base Tumors.
Management of Benign Skull Base Tumors in Neuro-oncology: Systemic Cytotoxic and Targeted Therapies.
Rehabilitation of Speech and Swallowing of Patients with Tumors of the Skull Base.
Neuropsychological Assessment of Patients with Skull Base Tumors.
Cerebrovascular Management in Skull Base Tumors.
Quality of Life and Measures of Outcome for Patients with Skull Base Tumors.
Pediatric Skull Base Surgery.
Site-Specific ConsiderationsSurgical Management of Tumors of the Nasal Cavity, Paranasal Sinuses, Orbit, and Anterior Skull Base.
Nasopharyngeal Carcinoma.
Clival Tumors.
Tumors of the Infratemporal Fossa.
Tumors of the Parapharyngeal Space.
Tumors of the Temporal Bone.
The Evaluation and Management of Sellar Tumors.
Tumors of the Cavernous Sinus and Parasellar Space.
Tumors of the Petrous Apex.
Tumors of the Cerebellopontine Angle.
Tumors of the Jugular Foramen.
Tumors of the Craniovertebral Junction.
Tumors of the Orbit.
Tumor-Specific ConsiderationsSquamous Cell Carcinoma of the Nasal Cavity and Paranasal Sinuses.
Nonsquamous Cell Carcinoma of the Nasal Cavity and Paranasal Sinuses.
Esthesioneuroblastoma.
Melanoma of the Nasal Cavity and Paranasal Sinuses.
Sarcomas of the Skull Base.
Angiofibromas and Other Vascular Tumors of the Skull Base.
Chordomas and Chondrosarcomas of the Skull Base.
Meningiomas.
Schwannomas of the Skull Base.
Paragangliomas of the Head and Neck.
Pituitary Adenomas.
Craniopharyngiomas.
Epidermoids, Dermoids, and Other Cysts of the Skull Base.
Fibro-Osseous Lesions of the Skull Base.