Wiley, 2010. - 481 p. - This book covers several major areas of modern research, development, and practical applications of molecular sciences. This text offers empirical-rational principles of broad relevance to scientists, professionals, and students interested in general aspectsof molecular discovery, as well as the thought processes behind experimental approaches. Empirical methods of discovery, along with serendipitous and rational design approaches, have played an important role in human history. the book compares empirical discovery strategies for biologically useful molecules with serendipitous discovery and rational design, while also considering the strengths and limitations of empirical pathways to molecular discovery. Logically arranged, this text examines the different modes of molecular discovery, empha-sizing the historical and ongoing importance of empirical strategies.
If It Works, It Works: Pragmatic Molecular Discovery
Empirical Miracles: Nature's Precedents for Empirical Solutions
Evolution's Gift: Natural Somatic Diversification and Molecular Design
Evolution While You Wait
The Blind Protein Maker
The Blind Shaper of Nucleic Acids
Evolving and Creating Recognition Molecules
Molecules Small and Large
An Empirical-Rational Loop Forwards
Exploring the Limits