World Scientific Pub, 2001. — 808 p.
Aimed at scientists and non-specialised readers alike, this book retraces the source of national and international biotechnology programmes by examining the origins of biotechnology and its political and economic interpretation by large nations. With a foreword by Andre Goffeau, who initiated the European Yeast Genome Project, the book describes the achievements of the first genetic and physical maps, as well as the political and scientific genesis of the American Human Genome Project. Following these advances, the author discusses the European biotechnology strategy, the birth and implementation of European biotechnology programmes and the yeast genome project. After a detailed description of scientific policy and administrative, technical and scientific achievements, the principal stages of the yeast project and its major benefits are discussed. This enables the reader to obtain a panoramic view of this developing discipline at the dawn of the 21st century, as well as a better knowledge of the means deployed at international level. The conclusion gives a very detailed account of the genesis and early stages of this new scientific and technological field called genomics which appears to be a key component of modern industry. By using an epistemological analysis, the conclusion poses the problem of a new representation of life and critically appraises the limitations and deficiencies.
Introduction: The Essence of Life and the Labyrinth of the Genome
The Invention of Biotechnology
Political Interpretations of Biotechnology and the Birth of the First Research Programs
The Foundations of the Heralded Revolution
Attack on the Genomes: The First Genetic and Physical Maps
The Human Genome Project and the International Sequencing Programs
European Biotechnology Strategy and Sequencing the Yeast Genome
The Decryption of Life
Conclusion: The Dreams of Reason or the New Biology's Dangerous Liaisons
Epilogue: Dreams or Nightmares? Man Reasoned out by His Genes
Acronyms