Luders H.O. Deep Brain Stimulation and Epilepsy

Boca Raton: CRC Press, 2020. — 385 p.Deep brain stimulation has been used effectively for many years to treat patients suffering from Parkinson's disease. Now, neurologists and neurosurgeons are using electric pulse generators to block abnormal activity, i.e. epileptic fits. Promising research results indicate that electric pulses implanted deep in the brain can affect neurocircuitry and help stop oncoming seizures. Supplying a solid background on brain stimulation and its application to epilepsy, Deep Brain Stimulation and Epilepsy provides a historical overview, explores pathogenesis of brain stimulation, discusses animal experiments and human studies, and explores future prospects of brain stimulation for epileptic control. The editor and his team of contributors distill information drawn directly from the literature into one convenient resource.Historical overview: brain stimulation and epilepsy
Brain stimulation and epilepsy: basic overview and novel approaches
Pathogenesis of brain stimulation: animal studies
The basal ganglia: an overview
The subthalamic nucleus: anatomy and neurophysiology
Brain stimulation and epilepsy: electrical stimulus characteristics
Electrically excitable nerve elements: excitation sites in peripheral and central stimulation
Control of neuronal activity by electrical fields: in vitro models of epilepsy
The nigral control of epilepsy: basal ganglia circuitry as a substrate for seizure control
High frequency direct cortical electrical stimulation: an animal model of induced acute focal seizures
Pathogenesis of brain stimulation: human studies
Cortico-coritcal evoked potentials
Repetitive transcranial magnetic stimulation
High frequency subthalamic nucleus stimulation
Cortical-evoked potentials from deep brain stimulation
EEG recording from the subthalamic nucleus in patients with epilepsy
EEG and the anterior thalamic nucleus
Effect of brain stimulation on epileptic seizures: animal experiments
Absence seizures in the GAERS model: subthalamic nucleus stimulation
Focal limbic seizures induced by kainic acid: effects of bilateral subthalamic nucleus stimulation
Focal stimulation versus deep brain stimulation
The anterior thalamus and the pentylenetetrazol (PTZ) model
Effect of brain stimulation on epileptic seizures: human studies
Vagal nerve stimulation: surgical technique
Vagal nerve stimulation: effects on seizures
Therapeutic prospects and safety of transcranial magnetic stimulation in epilepsy
Direct cortical electrical stimulation in the treatment of epilepsy
Electrical neuromodulation of the epileptic focus in cases of temporal lobe seizures
Anterior thalamic nucleus stimulation: surgical procedure
Anterior thalamic nucleus stimulation: issues in study design
Surgical procedure for subthalamic nucleus stimulation
Subthalamic nucleus and substantia nigra pars reticulata stimulation: the Grenoble experience
Subthalamic nucleus stimulation in patients with intractable epilepsy: the Cleveland experience
Brain stimulation: future prospects
The future of brain stimulation for seizure control