Pestell Richard G., Nevalainen Marja T. (eds.) Prostate Cancer: Signaling Networks, Genetics, and New Treatment Strategies

Humana Press, 2008. — 462 p. — ISBN: 978-1-58829-741-9Award winning authors present a comprehensive review of new perspectives in prostate cancer research and open up new directions in the clinical management of prostate cancer. In, "Prostate Cancer: Signaling Networks, Genetics, and New Treatment Strategies", the authors focus on the biology, genetics, molecular signaling networks in the disease process, and recent advances in the treatment of prostate cancer. This state-of-the-art title provides key insights into cutting edge advances in prostate cancer research, such as laparoscopic radical prostatectomy, and offers a critical evaluation and discussion of opportunities for development of novel therapies for prostate cancer. Clinical trials that have not been covered or evaluated in any other books currently available are also discussed. Invaluable to physicians and researchers, "Prostate Cancer: Signaling Networks, Genetics, and New Treatment Strategies" provides a comprehensive translational resource as well as an important source of information for prostate cancer patients.Histopathology and Molecular Biology of Prostate Atrophy
Epigenetic Gene Silencing in Prostate Cancer
Inherited Genetic Changes in Prostate Cancer
Prostate Molecular Oncogenesis
Somatic Genetic Changes in Prostate Cancer
Androgen Receptor in Prostate Cancer Progression
Epigenetic Modification and Acetylation of Androgen Receptor Regulate Prostate Cellular Growth
Estrogen Receptor α and β in the Regulation of Normal and Malignant Prostate Epithelium
Estrogen Action in Normal Prostate Epithelium and in Prostate Cancer
Hypoxia-Inducible Factor 1 in the Angiogenesis of Prostate Cancer
Signal Transduction by the Ras–MAP Kinase Pathway in Prostate Cancer Progression
Transcription Factors STAT5 and STAT3
Role of PI3K–Akt and PTEN in the Growth and Progression of Prostate Cancer
New Perspectives in Prediction of Clinical Outcome of Prostate Cancer
New Directions in Radiation Therapy of Prostate Cancer
The Current Knowledge of Hormonal Therapy in the Treatment of Prostate Cancer
Advances in Surgical Intervention of Prostate Cancer
Targeted Therapy Trials for Prostate Cancer
New Perspectives on Chemotherapy in Prostate Cancer
Concluding Remarks