Posten C. Integrated Bioprocess Engineering

De Gruyter, 2018. — 357 p. — (De Gruyter Textbook). — ISBN: 978-3-11-031538-7.Bioprocess engineering employs microorganisms to produce biological products for medical and industrial applications. The book covers engineering tasks around the cultivation process in bioreactors including topics like media design, feeding strategies, or cell harvesting. All aspects are described from conceptual considerations to technical realization. It gives insight to students of technical biology, bioengineering, and biotechnology by detailed explanations, drawings, formulas, and example processes. In Bioprocess Engineering upstream, bioreaction, and downstream stages are closely linked to each other. From a biological point of view photo-biotechnology is in the centre of interest as well as processes, where the particulate properties play an important role. The main technical means are fermentation under highly controlled conditions, mathematical modeling of bioprocesses including measurement of intracellular compounds, as well as mechanical separation methods arising from downstream processing.Introduction – a thread through this book
Biosystems – microorganisms and other biocatalysts
Media – supplying microorganisms with a comfortable environment and building blocks for growth
Kinetics – finding quantities for bioprocess reactions
Bioreactors – designing a home for the bioreaction
Not always so simple – the batch process reconsidered
Little by little one goes far – the fed-batch process
Microalgae – the solar cell factory
Continuously operating bioprocesses – production under steady state
conditions
Measuring principles – how to put an end to the blind flight
The practice of fermentation – a step by step guide through the workflow
Modeling – art and handcraft of mathematically describing bioprocesses