Wiranowska Marzenna, Vrionis Frank D. (eds.) Gliomas: Symptoms, Diagnosis and Treatment Options

Nova Science Publishers, 2013. — 414 p. — (Cancer Etiology, Diagnosis and Treatments) — ISBN: 978-1-62618-089-5In this book, the biology, current treatment modalities and new emerging therapeutic approaches and targets for glioma, a highly aggressive and invasive brain tumour, are described. The pathologic features of the most frequently WHO classified gliomas encountered in clinical practice, are reviewed. Molecular genetics and specifically the mutations that underlie brain tumours are outlined as is the inherited genetic susceptibility and lifestyle risk factors reflecting on glioma epidemiology. The clinical features of glioma as well as diagnostic methods that include conventional and advanced magnetic resonance imaging (MRI) and brain mapping are also discussed with an outline of emerging treatment options.Symptoms and Diagnosis
Epidemiology of Gliomas
Pathology of Gliomas
Molecular Genetics of Brain Tumors
Clinical Features of Central Nervous System Tumors
Neuro Imaging of Malignant Gliomas
Intra-operative Brain Mapping in Glioma Surgery
Preoperative Brain Mapping in Glioma Surgery
Current Treatment Options
Neurological Complications of Gliomas
Radiation Therapy in the Management of Glioma
Dose Rate Modulation for the Safe Delivery of Retreatment Irradiation in Recurrent Glioma Patients
Targeted Therapies for Malignant Gliomas
Antiangiogenic Therapies for High-Grade Glioma
CSF Dissemination of Gliomas and Primary Brain Tumors
Future Treatment Options: New Targets and Experimental Therapies
Stem Cell Biology as it Relates to Glioma Pathogenesis and Treatment
Glioma Extracellular Matrix Molecules as Therapeutic Targets
Current Immunotherapeutic Targets in Gliomas
The Significance of PTEN/Akt Pathway in Glioma and its Relation to Proliferation, Adhesion and Apoptosis of Glioma Cells
The Thiol Redox System in Glioma Biology: Clinical Target and Significance in Resistance to Glioma Chemotherapy
Loco-Regional and Targeted Therapy of Glioma with Chlorotoxin
Cytokine-Directed Recombinant Cytotoxins for Glioma Treatment
Nanoparticle Based Delivery of Therapeutics to Glioma