Kapp R.W., Tyl R.W. (Eds.) Reproductive Toxicology

3rd Edotion. — Informa Healthcare, 2010. — 422 p. — (Target Organ Toxicology Series). — ISBN13: 9781420073430.Thoroughly examining the popular and expanding field of reproductive toxicology, this newly revised and expanded third edition provides the latest, cutting-edge scientific developments in this constantly evolving discipline. Reproductive Toxicology's contributors are experienced regulatory agency and Clinical Research Organization representatives who currently utilize the new techniques discussed in the text and continue to revolutionize reproductive toxicology research.
This ground-breaking resource includes:
- New and important critical mechanistic topics such as epigenetics and omics
- The first significant compilation of epigenetic mechanisms
- An in-depth analysis of the role of genomics, proteomics, and metabolomicsin human reproduction
- New guidelines with respect to the latest research applications in the fieldNormal reproduction and development
Biology and physiology of fertilization
Normal development of the male reproductive system
Normal development of the female reproductive system
Development of the mammalian nervous system
Regulatory evaluation of reproduction
FDA and ICH perspectives on reproductive and developmental toxicology
EPA and OECD perspectives on reproductive and developmental toxicity testing
Reproductive study evolution and IND submissions for the Food and Drug Administration
Developmental toxicity of systemic organ systems
Developmental immunotoxicology
Developmental neurotoxicology
Developmental toxicology of the respiratory system
Developmental toxicity of the kidney
Developmental toxicology of the liver
Cardiovascular development and malformation
Toxicity of the reproductive process
Male reproductive toxicity
Female reproductive toxicity
Toxicity of the pregnant female reproductive system
Epigenetic reproductive toxicants
Cumulative effects of in utero administration to mixtures of reproductive toxicants in the male rat: a systems biology framework
Metals and metal compounds in reproductive and developmental toxicology
Omics in reproductive and developmental toxicology