Le Bihan Denis, Iima M. et al. (eds.) Intravoxel Incoherent Motion (IVIM) MRI: Principles and Applications

Pan Stanford Publishing, 2019. — 563 p. — ISBN: 9789814800198Intravoxel incoherent motion (IVIM) refers to translational movements which within a given voxel and during the measurement time present a distribution of speeds in orientation and/or amplitude. The concept was introduced in 1986 together with the foundation of diffusion MRI because it had been realized that flow of blood in capillaries (perfusion) would mimic a diffusion process and impact diffusion MRI measurements. IVIM-based perfusion MRI, which does not require injection of any tracer or contrast agent, has been first investigated in the brain, but is now experiencing a remarkable revival for applications throughout the body, especially for oncologic applications, from diagnosis to treatment monitoring. This book addresses a number of highly topical aspects of the field from leading authorities, introducing the concepts behind IVIM MRI, outlining related methodological issues, and summarizing its current usage and potential for clinical applications. It also presents future research directions, both in terms of methodological development and clinical application fields, extending to new, non-perfusion applications of IVIM MRI, such as virtual MR elastography.Introduction to IVIM MRI.
Introduction to IVIM MRI
Other MRI Approaches to Perfusion Imaging
Other MRI Approaches to Perfusion Imaging (ASL, DSC, DCE).
Clinical Applications of IVIM MRI: Neurological Applications
Clinical Applications of IVIM MRI to the Nervous System
IVIM MRI: A Window to the Pathophysiology Underlying Cerebral Small Vessel Disease
IVIM fMRI: Brain Activation with a High Spatial Specificity and Resolution
Clinical Applications of IVIM MRI: Body IVIM MRI
IVIM in the Body: A General Overview
Head and Neck IVIM MRI
IVIM MRI of the Breast
Cardiac IVIM MRI
Liver Fibrosis
Assessment of Liver Tumors with IVIM Diffusion-Weighted Imaging
IVIM MRI of the Pancreas
IVIM MRI in the Kidney
IVIM Diffusion Model in Prostate Cancer
Clinical Application of IVIM in the Female Pelvis
IVIM MRI of the Placenta
Fetal IVIM MRI
IVIM MRI and Bone Marrow
Next Frontiers of IVIM MRI
IVIM Models: Advantages, Disadvantages, and Analysis Pitfalls
Flow-Compensated IVIM in the Ballistic Regime: Data Acquisition, Modeling, and Brain Applications
Flow Compensation and Modeling of IVIM MRI in the Liver and Pancreas
Perfusion Marries Diffusion: Arterial Spin Labeling Prepared IVIM
Advanced Methods for IVIM Parameter Estimation
IVIM MRI Analysis with Low Perfusion
Synthetic and Physiological IVIM Complexity