Wahlgren Mats, Perlmann Peter (eds.) Malaria: Molecular and Clinical Aspects

Harwood Academic Publishers, 1999. — 576 p. — ISBN: 9789057024467.Malaria causes more death and disease than any other parasitic pathogen known today. This multiauthored text covers the important areas of malaria research, particularly focusing on those sectors which are of clinical importance for the understanding of the disease, the parasite, and its vector. The chapter authors are all leading experts within their own particular fields. The biology and molecular biology of the parasite, the clinical spectrum of the disease, the pathogenesis of malaria, and the immunology and emergence of malaria vaccines are some examples of the scientific spheres that are discussed.The book is suitable as a text for graduate students and clinicians as well as researchers at universities and companies involved in treating or studying infectious diseases.Milestones and Millstones in the History of Malaria
What is Malaria?
The Malaria Parasite and its Life-cycle
The Epidemiology of Malaria
Clinical Features of Malaria
Molecular Malariology
The Anopheles Mosquito: Genomics and Transformation
The Malaria Genome
The Malaria Antigens
Genetic Approaches to the Determinants of Drug Response, Pathogenesis and Infectivity in Plasmodium falciparum Malaria
The Sporozoite, the Merozoite and the Infected Red Cell: Parasite Ligands and Host Receptors
Pathogenesis and Resistance
Cytoadherence and Rosetting in the Pathogenesis of Severe Malaria
Inflammatory Processes in the Pathogenesis of Malaria
Inborn Resistance to Malaria
Burkitt’s Lymphoma and Malaria
Malaria Immunology and Vaccines
The Role of T Cells in Immunity to Malaria and the Pathogenesis of Disease
Malaria Vaccines
Synthetic Peptides as Malaria Vaccines
SPf66: The First and Towards the Second Generation of Malarial Vaccines