Pack Allan I. (ed.) Sleep Apnea: Pathogenesis, Diagnosis and Treatment

2nd edition. — Informa Healthcare, 2012. — 572 p. — ISBN: 9780849396977Sleep apnea is a common chronic condition affecting millions of people. Written by a multidisciplinary team including sleep medicine specialists, pulmonologists, scientists, psychiatrists, otorhinolaryngologists, and more, this text provides essential scientific and clinical information for those treating and researching the condition.Since the previous edition published, sleep medicine has become a fully formed medical speciality. This second edition has been expanded to contain more clinically relevant information regarding diagnosis and treatment. Organized into sections and subsections to make the book easier for the reader to use, this essential text also examines sleep apnea in special populations, such as children, older adults or pregnant women, and takes into account gender differences in the disorder.Pathogenesis of obstructive sleep apnea:Insights from upper airway imaging studies
Biomechanics of the upper airway during sleep
Sleep-induced breathing instability
Mechanisms of upper airway hypotonia
Autonomic consequences of arousal from sleep and neural mechanisms of arousal
Airway refl exes: Changes with sleep
Gender differences in sleep-disordered breathing
Mechanisms of sleepiness in obstructive sleep apnea
Neuroimaging studies in obstructive sleep apnea
Biomarkers and obstructive sleep apnea
Obstructive sleep apnea and hypertension: Interactions and clinical implications
Other cardiovascular consequences of sleep apnea
Neuroendocrine aspects of sleep apnea
Obstructive sleep apnea and glucose metabolism
Intermittent hypoxia and neurocognitive function
Obstructive sleep apnea: Mechanisms of intermittent hypoxemia neural injury
Screening for sleep apnea
Alternative strategies for diagnosis of patients with obstructive sleep apnea
Obstructive sleep apnea: Children versus adults
Sleep apnea in older adults
Obstructive sleep apnea in pregnancy and menopause
Adherence to CPAP treatment and functional status in adult obstructive sleep apnea
CPAP therapy: Results of randomized controlled trials in obstructive sleep apnea
Oral appliance therapy for snoringand sleep apnea
Upper airway surgery for obstructive sleep apnea
Pharmacotherapeutic trials for sleep-disordered breathing