Springer, 2019. — 347 p. — (Springer Series in Biomaterials Science and Engineering 13). — ISBN: 9811369232.
This book presents a comprehensive, state-of-the-art review of the latest progresses in UHMWPE biomaterials, which has been critical for the performance and longevity of joint implants. Oriented by clinical challenges to UHMWPE-based joint implants, it introduces the processing, crosslinking, structural manipulation, oxidation mechanism, stabilization, drug delivery, and wear, as well as clinical performance, biomechanics, and simulated studies of joint implant based on UHMWPE with low wear, which are aimed to tackle or minimize the adverse effect related to wear and wear debris. These contributions provide fundamentals of chemistry and physics of UHMWPEs to help understand the clinical performances of UHMWPE based joint implants. Perspectives to next generation UHMWPE to meet the unmet challenges in clinical use are included.
Clinical Applications of UHMWPE in Joint Implants
Highly Crosslinked UHMWPE for Joint Implants
Oxidation in Prosthetic UHMWPE
Natural Polyphenol-Stabilized Highly Cross-Linked UHMWPE for Joint Implants
High-Temperature Melted, Cross-Linked, and Stabilized Ultrahigh Molecular Weight Polyethylene
Drug-Loaded UHMWPE to Inhibit Wear Particle-Induced Osteolysis: Processing, Characterization, and Biological Evaluation
Biomechanics and Tribology of Artificial Knee Joint
Biomechanics and Biotribology of UHMWPE Artificial Hip Joints
Clinical Application of Roentgen Stereophotogrammetric Analysis Technique to Detect Hip Aseptic Loosening
Wear and Diagnostic Analysis of Clinical Failures of Artificial Hip Joints