Springer, 2019. — 352 p. — ISBN: 978-3-030-22671-8
This book provides a comprehensive, up-to-date overview of clinical and research aspects of cardiac repolarization geared toward practicing cardiologists and physicians. It analyzes elements of pathophysiology and molecular biology as they relate to the clinical aspects of cardiac repolarization, long QT syndromes, early repolarization syndromes, and special cardiac repolarization syndromes. Each chapter examines different aspects of the field with basic and clinical overviews and highlights the impact on medical management. The book covers a variety of repolarization topics including the influence of the autonomic system, racial and gender differences in patients, the future role of stem cells, inflammation and autoimmunity, and cardiovascular risk. Cardiac Repolarization: Basic Science and Clinical Management is an essential resource for physicians and related professionals, residents, fellows, and graduate students in cardiology, clinical cardiac electrophysiology, internal medicine, and cardiovascular biology.
Pathophysiology, Molecular Biology, and Clinical Aspects of Cardiac RepolarizationPhysiology and Molecular Biology of Ion Channels Underlying Ventricular Repolarization of the Mammalian Heart
Neuromodulation of Cardiac Repolarization and Arrhythmogenesis
Repolarization Remodeling in Structural Heart Disease
Cardiac Repolarization and Stem Cells: An Emerging Path Toward Precision Medicine
Role of Late Sodium Current During Repolarization and Its Pathophysiology
Age, Sex and Racial Differences in Cardiac Repolarization and Arrhythmogenesis
ECG-Derived Evaluation of Cardiac Repolarization
Pathophysiology, Molecular Biology, and Clinical Aspects of Long QT SyndromesGenotype-Phenotype Correlation in Congenital LQTS: Implications for Diagnosis and Risk Stratification
Clinical Management of LQTS Patients
Drug-Induced Long QT Syndrome and Torsades de Pointes
Acquired Long QT Syndrome and Electrophysiology of Torsade de Pointes
Pathogenesis of Autoimmune-Associated Long QT Syndrome
The Role of Inflammation and Autoimmunity in Long QT Syndrome
Pathophysiology, Molecular Biology, and Clinical Aspects of Early Repolarization SyndromesGenetics, Molecular Biology, and Emerging Concepts of Early Repolarization Syndrome
Electrocardiographic J Wave and Cardiovascular Risk in the General Population
Benign Versus Malignant Early Repolarization Patterns
Genetic Architecture, Pathophysiology, and Clinical Management of Brugada Syndrome
Pathophysiology and Clinical Aspects of Special Cardiac Repolarization SyndromesThe Short QT Syndrome
Microvolt T-Wave Alternans: Pathophysiology and Clinical Aspects
Action Potential Dynamics in Human Atrial Fibrillation