Liau L.M., Becker D.P., Cloughesy T.F., Bigner D.D. (eds.) Brain Tumor Immunotherapy

Humana Press, 2001. — 386 p. — ISBN: 978-0-89603-638-3.It is now clear from basic research and clinical trials that immunotherapy for brain tumors is feasible, can evoke relevant biologic responses, and can yield important insights into human biology. In Brain Tumor Immunotherapy, an authoritative panel of researchers and clinicians critically reviews the entire field to provide a comprehensive guide to modern brain tumor immunotherapy and thereby enhance future research in this area. The contributors detail many of the key laboratory experiments and clinical protocols that are currently being investigated, integrate the available information from previous and ongoing research, and help define the current status of the field. Topics range from adoptive cellular and antibody-mediated immunotherapy of brain tumors to tumor vaccines and related strategies, and include many vanguard experimental strategies and immunological techniques for studying tumor immunotherapy. Introductory material brings the reader up-to-date on the biological principles of brain tumor immunotherapy, along with the neuropathology, molecular pathogenesis, epidemiology, and the relevant current therapies.Cutting-edge and comprehensive, Brain Tumor Immunotherapy brings together all the important recent advances in our understanding of central nervous system tumor immunology and illustrates in powerful detail the many new applications now harnessing the immune response for brain tumor therapeutics.Neuropathology and Molecular Pathogenesis of Primary Brain Tumors
Epidemiology of Primary Brain Tumors
Current Therapy for Primary Brain Tumors
Immunostimulation and Immunomodulation of Brain Tumors
Biological Principles of Brain Tumor Immunotherapy
Systemic T-Cell Immunotherapy for Brain Tumors
Cytotoxic T-Lymphocytes Reactive to Patient Major Histocompatibility Complex Proteins for Therapy of Brain Tumors
Autologous Vaccine and Adoptive Cellular Immunotherapy as Treatment for Brain Tumors
Anti-Idiotype Immunotherapy Strategies for Brain Tumors
Radiolabeled Antibodies for Therapy of Brain Tumors
Immunotoxin Therapy of Brain Tumors
Antibodies to Adhesion Molecules for Immunotherapy of Brain Tumors
Cytokine-Based Immuno-Gene Therapy for Brain Tumors
Downregulation of Transforming Growth Factor β as Therapeutic Approach for Brain Tumors
Dendritic Cell Immunotherapy for Brain Tumors
Death Ligand/Death Receptor-Mediated Apoptosis for Treatment of Brain Tumors
Combining Radiation Therapy with Immunotherapy for Treatment of Brain Tumors