Sanoudou D. (ed.) Clinical Applications of Pharmacogenetics

InTech, 2012. - 305 p. - The rapidly evolving field of Pharmacogenetics aims at identifying the genetic factors implicated in the inter-individual variation of drug response. These factors could enable patient sub-classification based on their treatment needs thus expediting drug development and promoting personalized, safer and more effective treatments. This book presents Pharmacogenetic examples from a broad spectrum of different drugs, for different diseases, which are representative of different stages of evaluation or application. It has been designed so as to serve both the unfamiliar reader through explanations of basic Pharmacogenetic concepts, the clinician with presentation of the latest developments and international guidelines, and the research scientist with examples of Pharmacogenetic applications, discussions on the limitations and an outlook on the new scientific trends in this field.Pharmacogenetics: Matching the Right Foundation at Personalized Medicine in the Right Genomic Era
Multiplexed Pharmacogenetic Assays for SNP Genotyping: Tools and Techniques for Individualizing Patient Therapy
Role of Pharmacogenetics in Gastrointestinal Cancer
Pharmacogenomics of Thiopurine S-Methyltransferase: Clinical Applicability of Genetic Variants
S-Adenosylmethionine: A Novel Factor in the Individualization of Thiopurine Therapy
Current Status of Pharmacogenetics in Antithrombotic Drug Therapy
Clinical Implications of Genetic Admixture in Hispanic Puerto Ricans: Impact on the Pharmacogenetics of CYP2C19 and PON1
Neuropharmacogenetics of Major Depression: Has the Time Come to Take both Sexes into Account?
Pharmacogenetics of Asthma Pharmacogenomics in Gastroenterology
The Pharmacogenetics of the Antimalarial Amodiaquine
Pharmacogenetics and Obstetric Anesthesia and Analgesia
Beyond Pharmacogenetics