Kohn Brenda (ed.) Pituitary Disorders of Childhood: Diagnosis and Clinical Management

Humana Press, 2019. — 358 p. — (Contemporary Endocrinology) — ISBN: 978-3-030-11338-4This unique book presents an up-to-date discussion of clinical disorders of the pituitary gland in children with specific emphasis on state-of-the-art diagnostic and treatment modalities, highlighting the newest scientific advances in genomics and molecular biology that clinician-scientists caring for children need to know. Chapters focus on the current knowledge base in genomics, pathophysiology, diagnosis, and medical and surgical management, organized into thematic sections. Part I discusses embryologic and genetic disorders, including genomics and congenital disorders of the pituitary. Part II presents acquired pituitary disorders, such as prolactinomas, Cushing's Disease, and both hormone secreting and non-secreting pituitary tumors. Subsequent sections cover posterior pituitary disorders, such as diabetes insipidus, functional hormone deficiencies of the hypothalamic-pituitary axis, including delayed puberty and pubertal disorders and growth hormone disorders, neuro-opthalmic disease, CNS radiation, childhood cancer treatment and traumatic brain injury. Authoritative and comprehensive, Pituitary Disorders of Childhood will serve as a precise guide for clinical endocrinologists and will guide future investigation into translational and clinical research on the pediatric pituitary.Embryologic and Genetic Disorders of the Pituitary Gland
Embryologic and Genetic Disorders of the Pituitary Gland
Genetics of Hypopituitarism
Acquired Pituitary Disorders: Pituitary Tumors and Nonpituitary Sellar Masses
Adamantinomatous Craniopharyngioma: Genomics, Radiologic Findings, Clinical, and Prognosis
Prolactinomas
Cushing Disease: Diagnosis and Treatment
Surgery for Cushing’s Disease
Gigantism and Acromegaly
TSH-Secreting Pituitary Adenomas
Molecular Predictors of Clinical Behavior in Pituitary Adenohypophysial Tumors
Nonpituitary Sellar Masses and Infiltrative Disorders
Posterior Pituitary Disorders
Posterior Pituitary Disorders: Anatomy and Physiology, Central Diabetes Insipidus (CDI), and Syndrome of Inappropriate Antidiuretic Hormone (SIADH)
Functional Hypothalamic-Pituitary Hormone Deficiencies
Congenital Hypogonadotropic Hypogonadism (Isolated GnRH Deficiency)
Genetics of Delayed Puberty
Hypothalamic Amenorrhea
Neuro-Opthalmic Diseases
Neuro-Ophthalmic Diseases and Endocrinologic Function
CNS Radiation
Brain Irradiation Paradigms for Childhood Central Nervous System Tumors
Childhood Cancer Treatment
Hypothalamic: Pituitary Dysfunction as a Late Effect of Childhood Cancer, Brain Tumors, and Their Treatments
Traumatic Brain Injury
Pituitary Response to Traumatic Brain Injury