Klein Alberich (ed.) Neural Tube Defects: Prevalence, Pathogenesis and Prevention

Nova Science Publishers, 2013. — 170 p. — (Neurodevelopmental Diseases- Laboratory and Clinical Research) — ISBN: 978-1624178924Neural Tube Defects (NTDs) are congenital malformations of the central nervous system caused by partial or complete failure of the neural tube to close, within 28 days of conception. They represent the second most frequent cause of congenital abnormality. In this book, the authors discuss the prevalence, pathogenesis and prevention of neural tube defects. Topics include preconception folic acid as a primary prevention tool for NTD and its risk assessment; understanding and preventing folic acid-resistant neural tube defects; knowledge of the cellular mechanisms responsible for normal neural tube formation in comprehending and preventing NTDs; developmental delay in interneuron, motor neuron, sensory tract, and synapse formation in chick spina bifida; and an examination of whether neural tube defects lead to structural alterations in the urinary and genital organs in human fetuses.Prevalence, Pathogenesis and Prevention of Neural Tube Defects
Primary Prevention of Neural Tube Defects: Not Only Preconception Folic Acid Supplementation
Understanding and Preventing Folic Acid-Resistant Neural Tube Defects
Folic Acid, Homocysteine and Neural-Tube Defects
Developmental Delay in Interneuron, Motor Neuron, Sensory Tract, and Synapse Formation in Chick Spina Bifida
Do Neural Tube Defects Lead to Structural Alterations in the Urinary and Genital Organs in Human Fetuses?