2nd edition. — Academic Press, 2014. — 896 p. — ISBN: 9780124045996
In this second edition of Post-Genomic Cardiology, developing and new technologies such as translational genomics, next generation sequencing (NGS), bioinformatics, and systems biology in molecular cardiology are assessed in light of their therapeutic potential. As new methods of mutation screening emerge, both for the genome and for the “epigenome,” comprehensive understanding of the many mutations that underlie cardiovascular diseases and adverse drug reactions is within our reach.This book, written by respected cardiologist José Marín-García, features discussion on the Hap-Map: the largest international effort to date aiming to define the differences between our individual genomes. This unique reference further reviews and investigates genome sequences from our evolutionary relatives that could help us decipher the signals of genes, and offers a comprehensive and critical evaluation of regulatory elements from the complicated network of the background DNA.
Post-Genomic Cardiology
Pediatric Cardiology in the Post-Genomic Era
Post-Genomic Assessment of Coronary Artery Disease, Angiogenesis, and Hypertension
Post-Genomic Analysis of the Myocardium
Heart Failure, Cell Death, and Mitochondria Dynamics
Molecular and Genetic Analysis of Metabolic Disorders
Molecular Genetics of Dysrhythmias
Genes, Gender, and Epigenetics
Aging and the Cardiovascular System
Genetics, Epigenetics, and New Approaches to Treatment
Looking to the Future