Robinson Laura (ed.) A Practical Guide to Toxicology and Human Health Risk Assessment

Wiley-Blackwell, 2019. — 386 p. — ISBN: 9781118882078Toxicology – the study of the adverse effects of chemicals on living organisms is the cornerstone to all aspects of chemical safety and knowledge of the subject is needed in a wide spectrum of fields from the chemical industry to medicine, emergency services, forensics, and regulatory science. Toxicology involves the study of symptoms, mechanisms, treatments and detection of poisoning... especially the poisoning of people.The many problems arising from a poor understanding of toxicology and its applications in hazard communication and chemical safety motivated the author's training courses and webinars, leading to this valuable book.Providing a practical and accessible guide, A Practical Guide to Toxicology and Human Health Risk Assessment enables readers to quickly build up knowledge and understanding of toxicology and its use in hazard identification, which is a fundamental part of chemical risk assessment. The book also covers current toxicological testing strategies and the use of physicochemical test data in hazard identification and exposure assessment.Examples are provided throughout the book to highlight important issues along with a summary of the key points that have been covered in each of the respective chapters. The book concludes with a listing of online resources on toxicology and risk assessment.Welcome to the World of Toxicology
Basic Toxicological Terminology
The Dose Makes the Poison
Toxicokinetics
Factors That Modify Toxicity
Local Effects
Systemic Effects
Genetic Toxicology
Carcinogenicity
Reproductive and Developmental Toxicology
Target Organ Toxicity
The Kidney
The Immune System
Hematopoietic System and Blood
The Nervous System
The Respiratory Tract
Assessment Methods
Alternative Methods to Animal Testing
Human Health Risk Assessment