2nd Edition. — Academic Press, 2019. — 454 p. — ISBN 978-0-12-813259-3.
This book, Second Edition, provides an overview of skeletal biology, from the molecular level, to the organ level, including cellular control, interaction and response, adaptive responses to various external stimuli, and the interaction of the skeletal system with other metabolic processes in the body. The book includes chapters that address how the skeleton can be evaluated through the use of various imaging technologies, biomechanical testing, histomorphometric analysis, and the use of genetically-modified animal models. Each chapter delves deep into the important details of topics covered to provide a solid understanding of the basics of bone biology.
Bone biology researchers who also train undergraduate and graduate students in the lab will use this book constantly to orient new students on the basics of the field and as a background reference for many of the technical aspects of qualification in bone biology (e.g., mechanics, histomorphometry, genetic modification, biochemistry, etc.).
True PDFBasic Bone Biology and PhysiologyBone Morphology and Organization
Bone Marrow and the Stem Cell Niche
Bone Cells
Local Regulation of Bone Cell Function
Bone Growth, Modeling, and Remodeling
Assessment of Bone Structure and FunctionSkeletal Imaging
Skeletal Hard Tissue Biomechanics
Techniques in Histomorphometry
Skeletal Genetics: From Gene Identification
to Murine Models of Disease
Skeletal AdaptationSkeletal Changes Across the Life Span
Mechanical Adaptation
Fracture Healing
Hormonal and Metabolic Effects on Bone
The Interaction of Bone with Other Organ Systems
Skeletal Disease and Treatment