CRC Press, 2014. — 970 p. — ISBN: 978-1466584280
Gleaning information from more than 100 experts in the field of cancer diagnosis, prognosis, and therapy worldwide, Cancer Biomarkers: Non-Invasive Early Diagnosis and Prognosis determines the significance of clinical validation approaches for several markers. This book examines the use of noninvasive or minimally invasive molecular cancer markers that are under development or currently in use. It deals with a majority of commonly prevalent cancers and can help anyone working in the health-care industry to recommend or develop early diagnostics, at-risk tests, and prognostic biomarkers for various cancers.It explores the practice of determining biomarkers by their characteristics and relative methodologies, and presents the most recent data as well as a number of current and upcoming early diagnostic noninvasive molecular markers for many common cancers. It also considers the sensitivity and specificity of markers, biomarker market, test providers, and patent information.The book details the general and technical aspects of noninvasive cancer markers. It covers imaging, cutting-edge molecular technologies for biomarker development, and noninvasive or minimally invasive sources of molecular markers, as well as quality control and ethical issues in cancer biomarker discovery. It also provides a detailed account of brain, head and neck, and oral cancer markers, and provides information on a number of gastrointestinal cancers, lung cancer, and mesothelioma markers.This text considers molecular technologies for biomarker development, noninvasive or minimally invasive sources of molecular markers, and quality control and ethical issues in cancer biomarker discovery.
General and Technical AspectsQuality Control and Ethical Issues of Cancer Biomarker Discovery
Imaging Techniques in Cancer Diagnosis
Role of PET in Cancer Diagnosis
Innovative Tools for Early Detection of Cancer
Noninvasive Nanodiagnostics for Cancer
Mitochondrial DNA in Early Cancer Diagnosis and Screening
Circulating miRNA Biomarkers in Various Solid Cancers
Stem Cell Biomarkers in Early Diagnosis, Prognosis, and Therapy of Cancer
Salivary Biomarkers in Early Diagnosis and Monitoring of Cancer
Brain and Head and Neck CancersBiomarkers for Brain Gliomas
Noninvasive Biomarkers in Head and Neck Squamous Cell Carcinoma
Biological Markers in Oral Squamous Cell Carcinoma
Gastrointestinal CancersBiomarkers for Gastric Cancer and the Related Premalignant Conditions
Biomarkers in Esophageal Adenocarcinoma
Biomarkers for Diagnosis and Metastasis of Hepatocellular Carcinoma
Noninvasive Early Markers in Gallbladder Cancer
Noninvasive Early Markers in Pancreatic Cancer
Lung Cancer and MesotheliomaNoninvasive Early Markers in Lung Cancer
Exhaled Volatile Organic Compounds as Noninvasive Early Molecular Markers in Lung Cancer: Bridging the Gap from Bench to Bedside
Urological CancersNoninvasive Early Molecular Biomarkers in Kidney Cancer
Novel Oncomarkers Used for Earlier Detection of Bladder Carcinoma
Screening for Prostate Cancer: New Markers and Future Aspects
Gynecological and Endocrine CancersEarly Biomarkers in Breast Cancer
Noninvasive Biomarkers in Ovarian Cancer
Early Markers for Neoplastic Lesions of the Uterine Cervix
Biomarkers in Diagnosis of Papillary Thyroid Carcinoma
Biomolecular Markers for Improving Management of Follicular and Medullary Thyroid Cancer
Hematological CancersBiomarkers in Myelodysplastic Syndrome
Markers for Diagnosis, Prognosis, and Therapy of Acute Myeloid Leukemia
Biomarkers in Hodgkin’s Lymphoma
Multiple Myeloma and Evolution of Novel Biomarkers and Therapies
MelanomaDiagnostic and Prognostic Biomarkers in Cutaneous Melanoma