De Franchis Roberto (ed.) Portal Hypertension VI. Proceedings of the Sixth Baveno Consensus Workshop: Stratifying Risk and Individualizing Care

Springer International Publishing Switzerland, 2016. — 426 p.This book will be an excellent tool for practitioners seeking an update on the latest developments in the diagnosis and management of cirrhosis and portal hypertension. Among the topics addressed are risk stratification, prognosis, screening and surveillance, impact of etiological and antifibrotic therapy, the gut microbiome and cirrhosis, prevention of decompensation/further decompensation, management of the acute bleeding episode, controversies in pediatrics, and vascular diseases of the liver in cirrhotic and noncirrhotic portal hypertension. The book is a compilation of lectures and important consensus statements from the Sixth Baveno International Consensus Workshop on Portal Hypertension, the most recent of a series of workshops held every 5 years for hepatologists with an interest in the field. Portal Hypertension VI will serve as a reference book for clinical and research fellows in Gastroenterology and Hepatology and should inspire new research projects in the areas identified as promising by the experts of the Baveno VI Faculty.Risk Stratification and PrognosisThe Concept of Risk Stratification
Competing Risks and Prognostic Stages in Cirrhosis
Screening and Surveillance: Invasive and Noninvasive Methods
Results of the Questionnaire
Identifying Compensated Advanced ChronicLiver Disease: When (Not) to Start Screening for Varices and Clinically Significant Portal Hypertension.
How to Screen?
When and How to Perform Surveillance
Cost Considerations.
Consensus Statements: Session 1 — Screening and Surveillance
Changing Scenarios I: Impact of Etiological Therapyfor Cirrhosis and of Anti- fi brotic Therapyon Portal Hypertension
(Pre)Primary Prophylaxis: Where WereWe and Where Are We Heading?
Defi ning Clinical Hints to Predict Decompensationand Altering Paradigm in Patients with Cirrhosis
Antiviral Treatments and Residual Riskof Hepatic Decompensation
Etiological Treatments: Lifestyle Management.
Liver Fibrosis: What Is Reversible and What Not? How to Assess Regression?
Potential Antifi brotic Therapies: Approaching the Bedside: Proof-of- Concept Studies (Part 1)
New Targets in Therapy: Statins, Antioxidants and Antiangiogenic Strategies
Consensus Statements: Session 2 — Impact of Etiological and Anti-fi brotic Therapy
The Gut Microbiome and Cirrhosis
The Gut Microbiome and Cirrhosis: Basic Aspects
The Gut Microbiome and Cirrhosis: Clinical Aspects
Changing Scenarios II: What to Do After Successful Cure of the Etiologic Factor
Result of the Questionnaire.
Introduction: Prevention of Decompensation Versus Prevention of First Bleeding
Role of Comorbidities in the General Managementof Compensated Cirrhosis, Including Malnutrition
Primary Prophylaxis of First Variceal Bleeding
Endoscopic Band Ligation in Primary Prophylaxis
Consensus Statements: Changing Scenarios:
Prevention of Decompensation
Management of the Acute Bleeding Episode
Management of Acute Variceal Bleeding in Patientswith Cirrhosis: General Management, Drug Therapy, and Endoscopic Treatment
A la Carte Treatment of Acute Variceal Bleeding
Consensus Statements: Management of the Acute Bleeding Episode
Controversies and Challenges in Pediatrics
Portal Hypertension in Pediatrics: Controversies and Challenges 2015 Report
Prevention of Further Decompensation (Ascites, Spontaneous Bacterial Peritonitis, Hepatorenal Syndrome, Hepatic Encephalopathy)
Introduction and Survey Results
Prevention of Variceal Rebleeding:
Stratifying Risk and Individualizing Care
Secondary Prophylaxis in Special Patient Populations
Effect of Current Therapies Aimed at Preventing
Variceal Rebleeding on Other Complications of Cirrhosis
Impact of Treatment of Non-bleeding Complications of Cirrhosis on the Risk of Variceal Bleeding
Issues in Trial Design and Areas Needing Further Research
Consensus Statements: Preventing Recurrent Variceal Hemorrhage and Other Decompensating Events
Vascular Diseases of the Liver in Cirrhotic and Non-cirrhotic Portal Hypertension: Coagulation, Anti-coagulation, Anti-platelet Drugs
Results of the Questionnaire
Extrahepatic Portal Vein Obstruction (EHPVO) and Idiopathic Portal Hypertension: East Versus West
Budd-Chiari Syndrome/Hepatic Venous Outfl ow
Tract Obstruction: East vs West.
Antithrombotic Treatment in Cirrhosis.
Session 6: Consensus Statements – Vascular Diseases of the Liver in Cirrhotic and Noncirrhotic Portal Hypertension