Bradley John S., Nelson John D. (eds.) Nelson’s Pediatric Antimicrobial Therapy

25th edition. — American Academy of Pediatrics, 2019. — 331 p.
We are now in our 25th edition of Nelson’s Pediatric Antimicrobial Therapy, a tribute to John Nelson’s belief that advice on treatment of children with infections should be clear and concise! Although no new oral anti-infective agents have been approved in the United States recently, several antibiotics in many classes that completed adult studies are now entering pediatric clinical trials, particularly those for multidrug-resistant Gram-negative bacilli. The contributing editors, all very active in clinical work, have updates in their sections with relevant new recommendations based on current published data, guidelines, and clinical experience. We hope that the reference list for each chapter provides the available evidence to support our recommendations, for those who wish to see the data.Notable Changes to 2019 Nelson’s Pediatric Antimicrobial Therapy, 25th Edition.
Choosing Among Antibiotics Within a Class: Beta-lactams and Beta-lactamase Inhibitors, Macrolides, Aminoglycosides, and Fluoroquinolones.
Choosing Among Antifungal Agents: Polyenes, Azoles, and Echinocandins.
How Antibiotic Dosages Are Determined Using Susceptibility Data, Pharmacodynamics, and Treatment Outcomes.
Approach to Antibiotic Therapy of Drug-Resistant Gram-negative Bacilli and Methicillin-Resistant Staphylococcus aureus.
Antimicrobial Therapy for Newborns.
Antimicrobial Therapy According to Clinical Syndromes.
Preferred Therapy for Specific Bacterial and Mycobacterial Pathogens.
Preferred Therapy for Specific Fungal Pathogens.
Preferred Therapy for Specific Viral Pathogens.
Preferred Therapy for Specific Parasitic Pathogens.
Alphabetic Listing of Antimicrobials.
Antibiotic Therapy for Children Who Are Obese.
Sequential Parenteral-Oral Antibiotic Therapy (Oral Step-down Therapy) for Serious Infections.
Antimicrobial Prophylaxis/Prevention of Symptomatic Infection.
Appendix: Nomogram for Determining Body Surface Area.