Argiris Athanassios, Ferris R.L., Rosenthal David I. (eds.) Head and Neck Cancers: Evidence-Based Treatment

Demos Medical, 2018. — 553 p. — ISBN: 9780826137777Head and Neck Cancers: Evidence-Based Treatment presents a practical, state-of-the-art resource for any clinical oncologist treating or managing patients with head and neck cancers, including oropharyngeal cancer, cancer of the oral cavity, laryngeal cancer, nasopharyngeal cancer, hypopharyngeal cancer, cancer of the sinuses and the skull base, salivary gland cancer, and neck lymphadenopathy. Section 1 of the book covers the most pertinent details on the epidemiology, biology, diagnosis and staging of the disease including topics such as the genomic landscape of squamous cell carcinoma of the head and neck and novel imaging modalities. Section 2 discusses the evidence-based treatment modalities for conventional and novel chemotherapy regimens, the evidence behind emerging radiation therapy techniques and the minimally invasive surgical advances changing the landscape of care. The chapters in Section 3 are dedicated to site-specific management, including management guidelines, tables with FDA-approved therapies and relevant ongoing clinical trials as well as instructive clinical cases with important discussion on outcomes and follow up care. Finally, Section 4 focuses on recurrent and metastatic disease and Section 5 provides the essentials on supportive care, including managing the elderly, managing patients suffering from dysphagia and oral complications, and must-know details of quality of life assessment and patient-reported outcomes. Emphasizing the practice-changing techniques and the latest evidence-based treatment advances including targeted therapies, immunotherapy, transoral robotic surgery, and radiation therapy precision, this comprehensive yet accessible textbook is indispensable for any clinical oncologist of each discipline wanting a balanced and evidence-based reference on managing patients with head and neck malignancies.Epidemiology, Biology, Diagnosis, and Staging
Head and Neck Cancer Epidemiology
Pathology of HNSCC
The Genomic Landscape of HNSCC
HPV-Related Head and Neck Cancer Biology
Imaging of Head and Neck Cancers
Established and Emerging Treatment Modalities
Advances in Radiation Therapy Techniques for HNSCC: Image-Guided RT Stereotactic, IMRT-VMAT, MRI-Linac and Simulation
Proton Therapy
Transoral Robotic Surgery: Advances and Applications
Induction Chemotherapy: Current and Emerging Role in HNSCC
Immunotherapy for HNSCC: Rationale and Clinical Applications
Targeting the Human Epidermal Receptor Family in HNSCC
Therapies Targeting VEGF/Angiogenesis and Other Novel Targets and Therapies in HNSCC
Site-Specific Management
Oropharyngeal Cancer: HPV-Positive Disease
Non–HPV-Associated Oropharyngeal Cancer
Oral Cavity Cancer: Surgical Approaches and Postoperative Treatment
Nasopharyngeal Cancer
Hypopharyngeal Cancer: A Multidisciplinary Approach
Laryngeal Cancer: Organ Preservation Strategies
Malignancies of the Paranasal Sinuses and Skull Base
Evaluation and Treatment of Metastatic Lymphadenopathy From an Unknown Primary
Salivary Gland Malignancies
Recurrent or Metastatic Disease
Locally Recurrent HNSCC: Salvage Surgery, Reirradiation
Recurrent or Metastatic HNSCC: Systemic Therapy
Supportive Care and Special Patient Groups
Oral Complications
Dysphagia in Patients With Head and Neck Cancer
Quality of Life Assessment and Patient-Reported Outcomes in Head and Neck Cancer
Management of Head and Neck Cancers in the Elderly