Rajkumar S. Vincent, Kyle Robert A. (eds.) Treatment of Multiple Myeloma and Related Disorders

Cambridge University Press, 2009. — 216 p. — ISBN: 978-0-521-51503-0Due to major advances in understanding the biology and pathogenesis of the disease, the management of multiple myeloma is changing rapidly. New diagnostic and prognostic criteria have been introduced, and treatment options are multiplying with high-dose chemotherapy regimens, stem cell transplants, and the development of novel agents and immune-based strategies that target tumor cells directly. This book is aimed at the practitioner who is looking to put these advances into clinical context. It will serve as an up-to-date resource for treatment of myeloma and related disorders. Chapters are written by international authorities and contain color photos, diagrams, and algorithms outlining preferred treatment strategies. Relevant scientific information is integrated throughout, but the focus here is on providing practical therapeutic guidance for oncologists and hematologists caring for myeloma patients. The book covers all myeloma subtypes and related disorders, including amyloidosis, Waldenstrom macroglobulinemia, plasmacytoma, MGUS, and POEMS syndrome.Diagnosis and genetic classification of MM
Staging and risk-stratification of MM
Treatment of newly diagnosed MM
Maintenance therapy in MM
Treatment of relapsed and relapsed/refractory MM
Diagnosis and treatment of myeloma bone disease
Treatment of myeloma related complications
Autologous transplantation for MM
Allogeneic stem cell transplantation for MM
Immunoglobulin light chain amyloidosis (AL)
Waldenstrom's macrogloblinemia/lymphoplasmacytic lymphoma
Diagnosis, risk-stratification and management of solitary plasmacytoma
Monoclonal gammopathy of undetermined significance and smoldering multiple myeloma
Diagnosis and treatment of POEMS syndrome