Cambridge University Press, 2014. — 344 p. — ISBN: 9781139382816
Adult hydrocephalus is an insidious yet treatable condition that develops slowly, with usual onset around 60 years of age. It is poorly recognized and many cases are not diagnosed until late in the course of disease, leading to poorer patient outcomes and a high financial cost to healthcare providers. The resulting neurological symptoms include gait/balance problems, loss of bladder control, and a cognitive decline leading to dementia, which is often mistaken for Alzheimer's disease. This book - the first published on this topic since 1993 - provides comprehensive guidelines to improve the speed and accuracy of diagnosis, and covers various neurosurgical techniques used to treat the disease, including the insertion of different types of shunts and endoscopic third ventriculostomy. This is essential reading for neurologists, neurosurgeons, family physicians, and radiologists who may well encounter adult patients with hydrocephalus more often than they realize.
Basic sciencesAnatomy and physiology of the cerebrospinal fluid system
Neuropathology of human hydrocephalus
Animal models of hydrocephalus
Genetics of hydrocephalus
The epidemiology of hydrocephalus
PathophysiologyPathophysiology of gait dysfunction in normal pressure hydrocephalus
The pathophysiologic basis of cognitive dysfunction in idiopathic normal pressure hydrocephalus
Incontinence and lower urinary tract symptoms in normal pressure hydrocephalus
Normal pressure hydrocephalus grading scales
DiagnosisThe differential diagnosis of normal pressure hydrocephalus
Core imaging in adult hydrocephalus
Imaging of the cerebrospinal fluid circulation
Cerebrospinal fluid dynamics and infusion techniques
Monitoring of intracranial pressure and assessment of cerebrospinal fluid dynamics
Cerebrospinal fluid biomarkers in idiopathic normal pressure hydrocephalus
Treatment and outcomesHydrocephalus shunt procedures
Hydrocephalus shunts
Management of shunts in normal pressure hydrocephalus
Endoscopic third ventriculostomy
Outcome of idiopathic normal pressure hydrocephalus
Associated conditionsNormal pressure hydrocephalus syndrome secondary to hemorrhage, infection, and malignancy
Low-pressure syndromes and cerebrospinal fluid leaks
Management of the adult with congenital hydrocephalus
Management of hydrocephalus with associated cerebrospinal fluid pathologies
Chiari malformation and hydrocephalus in adults
Pseudotumor cerebri syndrome