Springer, 2016. — 494 p. — ISBN: 978-3-319-26049-5
This book offers a comprehensive overview of the state of the art in the practice of radioguided surgery. The opening section is devoted to the basic physics principles for detection and imaging, radiation detection device technology, principles of surgical navigation, radionuclides and radiopharmaceuticals, and radiation safety. A series of chapters then address the clinical application of radioguided surgery for a variety of malignancies, including breast cancer, melanoma and other cutaneous malignancies, gynecologic malignancies, head and neck malignancies, thyroid cancer, urologic malignancies, colon cancer, gastroesophageal cancer, lung cancer, bone tumors, parathyroid adenomas, and neuroendocrine tumors. For each application, the recommended methodological approaches are discussed and the available cumulative clinical experiences of investigators from across the globe are reviewed. A conscious effort is made to highlight recent developments and innovative multidisciplinary approaches within each clinical area. Interesting issues and novel approaches are further explored through a collection of selected case reports at the end of the book. The contributing authors are all experts in their own fields, ensuring that the book will hold wide appeal for surgeons, surgical technologists, nuclear medicine physicians, nuclear medicine technologists, and various trainees.
The History of Radioguided Surgery: Early Historical Milestones and the Development of Later Innovative Clinical Applications
Detailed Methodology PartPhysics of Radioguided Surgery: Basic Principles and Methods of Radiation Detection
The Use of Intraoperative Small and Large Field of View Gamma Cameras for Radioguided Surgery
urgical Navigation: An Overview of the State-of-the-Art Clinical Applications
Tracers Applied in Radioguided Surgery
Radiation Safety and Dosimetry
Clinical Application: BreastRadioguided Sentinel Lymph Node Mapping and Biopsy in Breast Cancer
Radioguided Surgery for Non-palpable Breast Lesions: I-125 Radioactive Seed Localization
Radioguided Surgery of Non-palpable Breast Lesions: Radio Occult Lesion Localization (ROLL)
Clinical Application: SkinRadioguided Sentinel Lymph Node Mapping and Biopsy in Cutaneous Melanoma
Clinical Application: Head and NeckRadioguided Sentinel Lymph Node Mapping and Biopsy in Oral Cancer
Clinical Application: Thyroid and ParathyroidRadioguided Sentinel Lymph Node Mapping and Biopsy in Thyroid Cancer
Radioguided Parathyroid Surgery
Radioguided Surgery of Thyroid Carcinoma Recurrences
Clinical Application: Urogenital TractRadioguided Sentinel Lymph Node Biopsy and Lymphatic Mapping in Urogenital Malignancies
Radioguided Sentinel Lymph Node Mapping and Biopsy in Gynaecological Malignancies
Clinical Application: Gastrointestinal TractRadioguided Sentinel Lymph Node Mapping and Biopsy in Esophagogastric Cancer
Radioguided Sentinel Lymph Node Mapping and Biopsy in Colorectal Cancer
Radioguided Surgery for Gastroenteropancreatic Neuroendocrine Tumors
Clinical Application: ThoracicRadioguided Sentinel Lymph Node Mapping and Biopsy in Non-small Cell Lung Cancer (NSCLC)
Radioguided Surgery of Small Pulmonary Nodules
MiscellaneousRadioguided Localization of Bone Lesions
Radioguided Monitoring of Systemic Leakage During Isolated Limb Perfusion for Melanoma
Radioimmunoguided Surgery: Intraoperative Radioimmunodetection for the Radioguided Localization and Resection of Tumors
18F-FDG-Directed Surgery and 18F-FDG-Directed Interventional Procedures
Outlook: New Techniques, Image Fusion, Optical ImagingFluorescent Tracers, Hybrid Tracers
Magnetic Advances in Cancer Surgery
Ultrasound Fusion (SPECT/US)
Examples (Conventional Techniques and Innovations)Case Reports