Dzau Victor J., Liew Choong-Chin (eds.) Cardiovascular Genetics and Genomics for the Cardiologist

Wiley-Blackwell, 2007. — 329 p. — ISBN: 978-1-405-13394-4Until recently, a modest knowledge of genetics was more than adequate for the daily practice of clinical cardiology, but advances in genetics and genomics are changing cardiovascular medicine in fundamental ways. The identification of the genetic basis of several forms of dyslipidemia, hypertension, diabetes, cardiomyopathies, and vascular diseases signalled the new importance of genetics in clinical medicine. Outstanding contributors write on their areas of expertise, making Cardiovascular Genetics and Genomics for the Cardiologist both authoritative and comprehensive. If you want to gain a better appreciation of how genetics and genomics are already shaping current practice and may potentially revolutionize cardiology, look no further than this dependable reference.The gene in the twenty-first century.
Cardiovascular single gene disorders.
Monogenic hypercholesterolemia.
Hypertrophic cardiomyopathy.
Dilated cardiomyopathy and other cardiomyopathies.
The long QT syndrome.
Cardiovascular polygenic disorders.
Atherosclerosis.
Heart failure.
The implications of genes on the pathogenesis, diagnosis and therapeutics of hypertension.
Therapies and applications.
Gene therapy for cardiovascular disease: inserting new genes, regulating the expression of native genes, and correcting genetic defects.
Stem cell therapy for cardiovascular disease.
Pharmacogenetics and personalized medicine.
The potential of blood-based gene profiling for disease assessment.