Brenner & Rector’s the kidney / [edited by] Karl Skorecki, Glenn M. Chertow, Philip A. Marsden,
Maarten W. Taal, Alan S.L. Yu ; special assistant to the editors, Walter G. Wasser. — 10th edition. — Elsevier, 2016. — 2636 p. — ISBN: 978-1-4557-4836-5
Overcome the toughest clinical challenges in nephrology with Brenner & Rector’s The Kidney -- the most well-known nephrology resource in the world. A diverse team of more than 200 international contributors brings you the latest knowledge and best practices on every front in nephrology worldwide. From basic science and pathophysiology to clinical best practices, Brenner & Rector’s The Kidney is your go-to resource for any stage of your career.
Key FeaturesReview of the basic science that underpins clinical nephrology, comprehensive selection of the most important bibliographical sources in nephrology, and Board Review-style questions help you prepare for certification or recertification.
Coverage of kidney health and disease from pre-conception through fetal and infant health, childhood, adulthood, and into old age. Expanded sections and chapter on global perspective and ethical considerations.
Uniform terminology and nomenclature in line with emerging consensus in world kidney community.
More than 700 full-color high-quality photographs as well as carefully chosen figures, algorithms, and tables to illustrate essential concepts, nuances of clinical presentation and technique, and decision making provide a visual grasp and better understanding of critical information.
New to this EditionInternationally diverse, trusted guidance and perspectives from a team of well-respected global contributors. An editorial team headed by Dr. Skorecki and handpicked by Dr. Brenner ensures the ongoing adherence to previous standards of excellence. All chapters have been extensively updated or entirely rewritten by authorities in their respective fields.
The latest clinical information including recent clinical trials, genetic causes of kidney disease, cardiovascular and renal risk prediction in chronic kidney disease, new paradigms in fluid and electrolyte management, and pediatric kidney disease, keep you current with the rapid development of care and research worldwide.
Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
I: Normal Structure and Function.
Embryology of the Kidney.
Anatomy of the Kidney.
The Renal Circulations and Glomerular Ultrafiltration.
The Podocyte.
Metabolic Basis of Solute Transport.
Transport of Sodium, Chloride, and Potassium.
The Regulation of Calcium, Magnesium, and Phosphate Excretion by the Kidney.
Renal Handling of Organic Solutes.
Renal Acidification Mechanisms.
Urine Concentration and Dilution.
The Cell Biology of Vasopressin Action.
Aldosterone and Mineralocorticoid Receptors: Renal and Extrarenal Roles.
Vasoactive Molecules and the Kidney.
Arachidonic Acid Metabolites and the Kidney.
II: Disorders of Body Fluid Volume and Composition.
Disorders of Sodium Balance.
Disorders of Water Balance.
Disorders of Acid-Base Balance.
Disorders of Potassium Balance.
Disorders of Calcium, Magnesium, and Phosphate Balance.
III: Epidemiology and Risk Factors in Kidney Disease.
Epidemiology of Kidney Disease.
Demographics of Kidney Disease.
Risk Factors and Chronic Kidney Disease.
Nephron Endowment and Developmental Programming of Blood Pressure and Renal Function.
Aging and Kidney Disease.
IV: Evaluation of the Patient with Kidney Disease.
Approach to the Patient with Kidney Disease.
Laboratory Assessment of Kidney Disease: Glomerular Filtration Rate, Urinalysis, and Proteinuria.
Interpretation of Electrolyte and Acid-Base Parameters in Blood and Urine.
Diagnostic Kidney Imaging.
The Kidney Biopsy.
Biomarkers in Acute and Chronic Kidney Diseases.
V: Disorders of Kidney Structure and Function.
Acute Kidney Injury.
Primary Glomerular Disease.
Secondary Glomerular Disease.
Overview of Therapy for Glomerular Disease.
Microvascular and Macrovascular Diseases of the Kidney.
Tubulointerstitial Diseases.
Urinary Tract Infection in Adults.
Urinary Tract Obstruction.
Diabetic Nephropathy.
Urolithiasis.
Kidney Cancer.
Onco-Nephrology: Kidney Disease in Patients with Cancer.
VI: Genetics of Kidney Disease.
Genetic Basis of Kidney Disease.
Inherited Disorders of the Glomerulus.
Inherited Disorders of the Renal Tubule.
Cystic Diseases of the Kidney.
VII: Hypertension and the Kidney.
Primary and Secondary Hypertension.
Renovascular Hypertension and Ischemic Nephropathy.
Hypertension and Kidney Disease in Pregnancy.
Antihypertensive Therapy.
Diuretics.
VIII: The Consequences of Advanced Kidney Disease.
Adaptation to Nephron Loss and Mechanisms of Progression in Chronic Kidney Disease.
Mechanisms and Consequences of Proteinuria.
The Pathophysiology of Uremia.
Chronic Kidney Disease-Mineral Bone Disorder.
Cardiovascular Aspects of Kidney Disease.
Hematologic Aspects of Kidney Disease.
Endocrine Aspects of Chronic Kidney Disease.
Neurologic Aspects of Kidney Disease.
Dermatologic Conditions in Kidney Disease.
IX: Conservative Management of Kidney Disease.
Dietary Approaches to Kidney Diseases.
A Stepped Care Approach to the Management of Chronic Kidney Disease.
Therapeutic Approach to Chronic Kidney Disease-Mineral and Bone Disorder.
Drug Dosing Considerations in Patients with Acute Kidney Injury and Chronic Kidney Disease.
X: Dialysis and Extracorporeal Therapies.
Hemodialysis.
Peritoneal Dialysis.
Critical Care Nephrology.
Plasmapheresis.
Elimination Enhancement of Poisons.
Interventional Nephrology.
XI: Kidney Transplantation.
Transplantation Immunobiology.
Clinical Management of the Adult Kidney Transplant Recipient.
XII: Pediatric Nephrology.
Malformation of the Kidney: Structural and Functional Consequences.
Diseases of the Kidney and Urinary Tract in Children.
Fluid, Electrolyte, and Acid-Base Disorders in Children.
Renal Replacement Therapy (Dialysis and Transplantation) in Pediatric End-Stage Kidney Disease.
XIII: Global Considerations in Kidney Disease.
Latin America.
Africa.
Near and Middle East.
Indian Subcontinent.
The Far East.
Oceania Region.
XIV: Challenges in Nephrology.
Ethical Dilemmas Facing Nephrology: Past, Present, and Future.
Health Disparities in Nephrology.
Care of the Older Person with Chronic Kidney Disease.
Tissue Engineering, Stem Cells, and Cell Therapy in Nephrology.
Quality Improvement Initiatives in Kidney Disease.