Dong C., Zahir N., Konstantopoulos K. (Eds.) Biomechanics in Oncology

Springer, 2018. — 378 p. — (Advances in Experimental Medicine and Biology 1092). — ISBN: 978-3-319-95293-2.This book covers multi-scale biomechanics for oncology, ranging from cells and tissues to whole organ. Topics covered include, but not limited to, biomaterials in mechano-oncology, non-invasive imaging techniques, mechanical models of cell migration, cancer cell mechanics, and platelet-based drug delivery for cancer applications. This is an ideal book for graduate students, biomedical engineers, and researchers in the field of mechanobiology and oncology.
This book also:
Describes how mechanical properties of cancer cells, the extracellular matrix, tumor microenvironment and immuno-editing, and fluid flow dynamics contribute to tumor progression and the metastatic process
Provides the latest research on non-invasive imaging, including traction force microscopy and brillouin confocal microscopy
Includes insight into NCIs’ role in supporting biomechanics in oncology research
Details how biomaterials in mechano-oncology can be used as a means to tune materials to study cancerThe National Cancer Institute Investment in Biomechanics in Oncology Research
DNA Mechanics and Topology
Mechanics of the Cell Nucleus
Extracellular Matrix Stiffness Exists in a Feedback Loop that Drives Tumor Progression
Microenvironment Influences Cancer Cell Mechanics from Tumor Growth to Metastasis
Mechanical Forces in Tumor Angiogenesis
From Cancer Immunoediting to New Strategies in Cancer Immunotherapy: The Roles of Immune Cells and Mechanics in Oncology
Exposing Cell-Itary Confinement: Understanding the Mechanisms of Confined Single Cell Migration
Modeling Cell Migration Mechanics
Engineered Models of Metastasis with Application to Study Cancer Biomechanics
Biomechanics of the Circulating Tumor Cell Microenvironment
Platelet-Based Drug Delivery for Cancer Applications
Biomaterials in Mechano-oncology: Means to Tune Materials to Study Cancer
Design of Fiber Networks for Studying Metastatic Invasion
Traction Force Microscopy for Noninvasive Imaging of Cell Forces
Noninvasive Imaging: Brillouin Confocal Microscopy