Barker Peter B., Bizzi Alberto, De Stefano Nicola et al. (eds.) Clinical MR Spectroscopy: Techniques and Applications

Cambridge University Press, 2010. — 275 p. — ISBN: 9780511770647In vivo magnetic resonance spectrosopy (MRS) is increasingly being used in the clinical setting, particularly for neurological disorders. Clinical MR Spectroscopy – Techniques and Applications explains both the underlying physical principles of MRS and provides a perceptive review of clinical MRS applications. Topics covered include an introduction to MRS physics, information content of spectra from different organ systems, spectral analysis methods, recommended protocols and localization techniques, and normal age- and region-related spectral variations in the brain. Clinical applications in the brain are discussed for brain tumors, hypoxic and ischemic injury, infectious, inflammatory and demyelinating diseases, epilepsy, neurodegenerative disorders, trauma and metabolic diseases. Outside of the brain, techniques and applications are discussed for MRS in the musculosketal system, breast and prostate. Written by leading MRS experts, this is an invaluable guide for anyone interested in in vivo MRS, including radiologists, neurologists, neurosurgeons, oncologists and medical researchers.Introduction to MR spectroscopy in vivo
Pulse sequences and protocol design
Spectral analysis methods, quantitation, and common artifacts
Normal regional variations: brain development and aging
MRS in brain tumors
MRS in stroke and hypoxic–ischemic encephalopathy
MRS in infectious, inflammatory, and demyelinating lesions
MRS in epilepsy
MRS in neurodegenerative disease
MRS in traumatic brain injury
MRS in cerebral metabolic disorders
MRS in prostate cancer
MRS in breast cancer
MRS in musculoskeletal disease