Kim Nayoung (ed.) Helicobacter pylori

Springer, 2016. — 532 p. — ISBN: 978-981-287-706-2This book presents the current state of knowledge regarding the ability of Helicobacter pylori to colonize the gastrointestinal tract, the global epidemiology of H. pylori infection, transmission routes, the pathophysiology of H. pylori-related gastroduodenal and other diseases, diagnosis and treatment methods, guidelines for eradication, antibiotic resistance, the reinfection rate after H. pylori eradication, and animal models of H. pylori or related Helicobacter infection. The aim is to equip readers around the world with the understanding required in order to implement effective methods of H. pylori eradication and to enhance clinical outcomes for patients. The text is clearly written and is complemented by many helpful illustrations. This book will be a great asset in clinical practice for all practitioners who are involved in caring for patients with H. pylori-related diseases or have an interest in the subject. It will also be a useful source of information for medical students and for intelligent laypeople seeking information on H. pylori.Epidemiology
Prevalence and Transmission Routes of H. pylori
Gastric Colonization by H. pylori
Immunological Reactions on H. pylori Infection
Change of Acid Secretions, Ghrelin and Leptin, by H. pylori
H. pylori Virulence Factors: Toxins (CagA, VacA, DupA, OipA, IceA)
H. pylori Virulence Factors: Genetic Polymorphism and Disease
Host Factor: Genetic Polymorphism
Diagnosis
Serology
Histopathologic Diagnosis of H. pylori Infection and Associated Gastric Diseases
Culture
Urea Breath Test
H. pylori Stool Antigen Test
Specific Conditions: Children
Specific Conditions: Diagnosis of H. pylori Infection in Case of Upper Gastrointestinal Bleeding
Symptom
Symptoms of Acute and Chronic H. pylori Infection
Disease
Synopsis of H. pylori-Associated Diseases
Atrophic Gastritis and Intestinal Metaplasia
Functional Dyspepsia
Peptic Ulcer
Gastric Extranodal Marginal Zone B-Cell Lymphoma of MALT
Gastric Cancer: Synopsis and Epidemiology of Gastric Cancer
Gastric Cancer: Genetic Alternations Induced by H. pylori Infection: The Role of Activation- Induced Cytidine Deaminase
Gastric Cancer: Epigenetic Mechanisms: Aberrant DNA Methylation and Dysregulation of MicroRNA
Gastric Cancer: H. pylori and Macrophage Migration Inhibitory Factor
Gastric Cancer: Epithelial Mesenchymal Transition
Gastric Cancer: ABO Blood Type
Gastric Cancer: First Relatives of Gastric Cancer
H. pylori Infection-Negative Gastric Cancer
Gastroesophageal Reflux Disease
NSAID-Induced Gastropathy and H. pylori Infection
Extraintestinal Manifestations of H. pylori Infection: H. pylori- Associated Iron-Deficiency Anemia
Extraintestinal Manifestations of H. pylori Infection: Idiopathic Thrombocytopenic Purpura
Extraintestinal Manifestations of H. pylori Infection: Heart Disease
Extraintestinal Manifestations of H. pylori Infection: Asthma and Allergic Disorders
Antibiotic Resistance
Synopsis of Antimicrobial Resistance
Clarithromycin
Amoxicillin
Fluoroquinolone
Metronidazole
Treatment
Synopsis of Antibiotic Treatment
Triple Therapy
Quadruple Therapy
Sequential Therapy
Concomitant Therapy and Hybrid Therapy
Tailored Therapy Based on Antibiotic Resistance
Levofloxacin or Rifabutin-Based Triple Therapy
Probiotics
Treatment Guidelines
Gastric Cancer Screening
Recrudescence and Reinfection After H. pylori Eradication Treatment Eradication Treatment
Consequences of H. pylori Eradication
Peptic Ulcer Disease
Atrophic Gastritis and Intestinal Metaplasia
Gastric Cancer
The Effect of H. pylori Infection on the Gastric Microbiota
The Effect of H. pylori Infection on the Gastric Microbiota
Animal Model
Animal Models of H. pylori Infection