Suzuki Hidekazu, Warren Robin, Marshall Barry (eds.) Helicobacter pylori

Springer, 2016. — 265 p. — ISBN: 978-4-431-55705-0This book provides a detailed review of the most recent pathogenetic, diagnostic and therapeutic approaches in connection with Helicobacter pylori, along with priority areas in research and trends in clinical practice to address this significant pathogen acknowledged as the causative agent in a wide range of diseases, including gastric adenocarcinoma, MALT lymphoma and immune thrombocytopenic purpura (ITP). Medical authorities worldwide now recommend a “test and treat” strategy for this bacterial infection. Eradication therapy approaches range from general mass eradication therapy to tailor-made therapy for antibiotic-resistant refractory infection. In regions with high prevalence of H. pylori infection, the infection itself would be considered a major parameter to predict the risk of gastric adenocarcinoma development. The main interest has shifted recently to the risk stratification strategy for gastric cancer development and to the wide-ranging application of its serological prevention program.This book will benefit all gastroenterologists, hematologists, dermatologists, primary care doctors, epidemiologists, physicians who related with community hygiene, as well as basic scientists, particularly microbiologists, bacteriologists, pathologists, molecular biologists, biochemists, immunologists and oncologists.History
A Brief History of the Discovery of Helicobacter pylori
Pathogenesis
Human Migration
CagA
Helicobacter pylori VacA Exhibits Pleiotropic Actions in Host Cells
Autophagy
Ghrelin and Gut Hormone
Symptom Generation
Gastric Non-Helicobacter pylori Helicobacter: Its Significance in Human Gastric Diseases
Diagnosis
Urea Breath Test and Rapid Urease Test
Endoscopic Findings of H. pylori Infection
Stratification of Gastric Cancer Risk by H. pylori Infection
Prevention of Gastric Cancer by Helicobacter pylori Eradication: Current Evidence and Future Prospects
Treatment
Trends in Global Eradication Rates
Personalized Therapy in H. pylori Eradication
Quadruple Regimens for Helicobacter pylori Infection
Third-Line Eradication Therapy