Yankeelov Th., Price R.R., Pickens D.R. (eds.) Quantitative MRI in Cancer

CRC Press, 2012. — 310 p. — ISBN: 1439820570,9781439820575,9781439820582.Propelling quantitative MRI techniques from bench to bedside, Quantitative MRI in Cancer presents a range of quantitative MRI methods for assessing tumor biology. It includes biophysical and theoretical explanations of the most relevant MRI techniques as well as examples of these techniques in cancer applications. The introductory part of the book covers basic cancer biology, theoretical aspects of NMR/ MRI physics, and the hardware required to form MR images. Forming the core of the book, the next three parts illustrate how to characterize tissue properties with endogenous and exogenous contrast mechanisms and discuss common image processing techniques relevant for cancer. The final part explores emerging areas of MR cancer characterization, including radiation therapy planning, cellular and molecular imaging, pH imaging, and hyperpolarized MR. Each of the postintroductory.
chapters describes the salient qualitative and quantitative aspects of the techniques before proceeding to preclinical and clinical applications. Each chapter also contains references for further study.FeaturesShows how MRI is used today for the diagnosis and therapy monitoring of cancer.
Discusses qualitative and quantitative aspects of the techniques.
Presents a detailed treatment of the state of the art in tissue characterization using endogenous and exogenous contrast agents.
Covers image processing in cancer.
Explores emerging trends in MR characterization, such as radiation therapy planning, molecular and cellular imaging, and hyperpolarized MR.
Leading the way toward more personalized medicine, this text brings together existing and emerging quantitative MRI techniques for assessing cancer. It provides a self-contained overview of the theoretical and experimental essentials and state of the art in cancer MRI.Physical Basis of Magnetic Resonance Imaging.
The Biology and Imaging of Cancer.
Physics of MRI.
Magnetic Resonance Imaging: Hardware and Data Acquisition.
Image Formation.
Characterizing Tissue Properties with Endogenous Contrast Mechanisms.
Quantitative Measurement of T1, T2, T2∗, and Proton Density.
Arterial Spin Labeling Techniques.
Diffusion-Weighted MRI.
Magnetization Transfer and Chemical Exchange Saturation Transfer Imaging in Cancer Imaging.
MR Spectroscopy and Spectroscopic Imaging of Tumor Physiology and Metabolism.
Characterizing Tissue Properties with Exogenous Contrast Agents.
Contrast Agents for T1-Weighted MRI.
Nanoparticles for T2- and T2 ∗-Weighted MRI.
Dynamic Contrast-Enhanced MRI: Data Acquisition and Analysis.
Dynamic Susceptibility MRI: Data Acquisition and Analysis.
Magnetic Resonance Angiography.
Image Processing in Cancer.
Imaging Tissue Oxygenation Status with MRI.
Clinical Assessment of the Response of Tumors to Treatment with MRI.
Image Segmentation.
Spatial and Temporal Image Registration.
Synthesis of Multiparametric Data.
Emerging Trends.
MRI in Radiation Therapy Planning.
Molecular and Cellular Imaging.
Hyperpolarized MR of Cancer.