Martín M.L.G., Larrubia P.L. (Eds.) Preclinical MRI: Methods and Protocols

New York, Humana Press, 2018. — 464 p. — (Methods in Molecular Biology 1718). — ISBN: 978-1-4939-7530-3,978-1-4939-7531-0.This volume discusses a variety of preclinical MRI methods and protocols to help technicians and researchers conduct studies in their respective fields. This book is organized into 7 parts: Part 1 covers the basics of MRI physics, relaxation, image contrast, and main acquisition sequences; Part 2 describes methodologies for diffusion, perfusion, and functional imaging; Part 3 looks at in vivo spectroscopy; Part 4 explores special MRI techniques that are less known in the field; Parts 5 and 6 discuss MRIs and MRSs in animal models of disease and the applications used to study them, and Part 7 looks at anesthesia and advanced contrast agents. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoidin.MRI Bsics
Introduction to MRI Physics
Basic Pulse Sequences in Magnetic Resonance ImagingPerfusion, diffusion and functional MRI
Dynamic Susceptibility Contrast MRI in Small Animals
Preclinical Arterial Spin Labeling Measurement of Cerebral Blood Flow
Dynamic Contrast-Enhanced MRI
Diffusion-Weighted Magnetic Resonance Imaging
Diffusion Tensor Imaging (DTI)
Mapping Functional Connectivity in the Rodent Brain Using Electric-Stimulation fMRI
Functional Diffusion Magnetic Resonance ImagingIn Vivo Spectroscopy
In Vivo 1H Magnetic Resonance Spectroscopy
In Vivo Heteronuclear Magnetic Resonance Spectroscopy
1H Spectroscopic Imaging of the Rodent BrainSpecial MRI Techniques
Susceptibility Weighted MRI in Rodents at 9.4 T
Biomedical 19F MRI Using Perfluorocarbons
Rodent Abdominal Adipose Tissue Imaging by MR
Cardiac MRI in Small Animals
In Utero MRI of Mouse Embryos
Oxygenation Imaging by Nuclear Magnetic Resonance Methods
Molecular Magnetic Resonance Imaging (mMRI)MRI and MRS in Animal Models of Disease
Magnetic Resonance Spectroscopy Studies of Mouse Models of Cancer
MRI in the Study of Animal Models of Neurodegenerative Diseases
MRI in the Study of Animal Models of StrokeOther Applications
Assessment of Blood Brain Barrier Leakage with Gadolinium-Enhanced MRI
In Vivo Pharmacokinetics of Magnetic NanoparticlesAnesthesia And Advanced Contrast Agents
Anesthesia and Monitoring of Animals During MRI Studies
Advanced Contrast Agents for Multimodal Biomedical Imaging Based on Nanotechnology