Koehn Frank E. (ed.) Natural Products and Cancer Drug Discovery

Humana Press, 2013. — 248 p. — (Cancer Drug Discovery and Development).This volume will cover the natural products as they relate to cancer chemotherapy. The topics will include history and current status , recent launches, new clinical candidates and approved drugs directly derived from natural products, current and future cancer target opportunities for natural products, leveraging natural products as tools for new target generation , new approaches to cancer drug discovery through natural products based lead generation, and enabling technologies which leverage the unique attributes of natural products.The Impact of Natural Products Upon Cancer Chemotherapy
Identification and Development of Vascular Disrupting Agents: Natural Products That Interfere with Tumor Growth
Discodermolide: Past, Present, and Future
HDAC Inhibitors and Other Histone Modifying Natural Products as Emerging Anticancer Agents
Natural Product Cytotoxins as Payloads for Antibody Drug Conjugates
Natural Product Scaffolds in Cancer Therapy
The Role of Genetic Engineering in Natural Product-Based Anticancer Drug Discovery
Accessing Anti-cancer Natural Products by Plant Cell Culture
Natural Products as Tools for Discovering New Cancer Targets