S. Karger, 2007. — 359 p. — (Progress in Respiratory Research, Vol. 36).
Diffuse parenchymal lung disease (DPLD) represents a large and heterogeneous group of disorders. Although new insights into the pathogenesis and new techniques such as high-resolution-CT have led to a better understanding of DPLD, clinical management remains a challenge.This volume is designed to become a valuable aid in the diagnosis and management of DPLD. It starts with general topics such as a new classification system for DPLD, the general diagnostic approach, and clinical evaluation of the patient by radiology, histological patterns and bronchoalveolar lavage. This is followed by consideration of some basic aspects such as the genetics of DPLD, the principles of granuloma formation, pulmonary fibrogenesis and vasculitis, as well as novel treatment approaches. A large part of the book consists of disease-specific chapters, which discuss granulomatous disorders, idiopathic pulmonary fibrosis and other entities of idiopathic interstitial pneumonia, the collagen vascular diseases, drug-induced infiltrative lung disease as well as orphan diffuse lung diseases including Langerhans’ cell histiocytosis, lymphangioleiomyomatosis and pulmonary alveolar proteinosis. Special chapters on DPLD in children and lung transplantation for end-stage fibrosis complete this comprehensive publication.This volume is designed to become a valuable aid in the diagnosis and management of DPLD. It starts with general topics such as a new classification system for DPLD, the general diagnostic approach, and clinical evaluation of the patient by radiology, histological patterns and bronchoalveolar lavage. This is followed by consideration of some basic aspects such as the genetics of DPLD, the principles of granuloma formation, pulmonary fibrogenesis and vasculitis, as well as novel treatment approaches. A large part of the book consists of disease-specific chapters, which discuss granulomatous disorders, idiopathic pulmonary fibrosis and other entities of idiopathic interstitial pneumonia, the collagen vascular diseases, drug-induced infiltrative lung disease as well as orphan diffuse lung diseases including Langerhans’ cell histiocytosis, lymphangioleiomyomatosis and pulmonary alveolar proteinosis. Special chapters on DPLD in children and lung transplantation for end-stage fibrosis complete this comprehensive publication.
General AspectsClassification of Diffuse Parenchymal Lung Disease
Diagnostic Approach to Diffuse Parenchymal Lung Disease
Clinical Evaluation
Imaging
Diffuse Parenchymal Lung Diseases – Histopathologic Patterns
Bronchoalveolar Lavage
Basic AspectsGenetics of Interstitial Lung Disease
Granuloma Formation
Pathogenesis of Idiopathic Pulmonary Fibrosis
Basics of Pulmonary Vasculitis
Novel Aspects of Treatment for Interstitial Lung Diseases
DiseasesSarcoidosis
Hypersensitivity Pneumonitis
Idiopathic Pulmonary Fibrosis
Nonspecific Interstitial Pneumonia
Diseases: Other Entities of the Idiopathic Interstitial Pneumonias
Pulmonary Fibrosis in Collagen Vascular Disease
Pulmonary Vasculitis
Drug-Induced and Iatrogenic Infiltrative Lung Disease
Idiopathic Eosinophilic Pneumonias
Diffuse Alveolar Hemorrhage
Pulmonary Langerhans’ Cell Histiocytosis
Lymphangioleiomyomatosis
Acquired Idiopathic Pulmonary Alveolar Proteinosis
Bronchiolitis
Lymphoproliferative Lung Disorders
Interstitial Lung Diseases in Children
Lung Transplantation for Diffuse Parenchymal Lung Disease