Genazzani Andrea R. (ed.) Postmenopausal Osteoporosis: Hormones & Other Therapies

CRC Press, 2013. — 319 p. — (Controversal Issues in Climacteric Medicine).The book is the first major review of menopause-associated osteoporosis, post WHI. The book has in-depth sections on the pathogenesis, epidemiology, and diagnosis of osteoporosis. The chief focus is on medical prevention and treatment, and includes chapters on hormone replacement therapy, bisphosphonates, selective estrogen receptor modulators (SERMs), vitamin D derivatives, calcium supplements, androgens, and tibolone.Magnitude and impact of osteoporosis and fractures
Impact of osteoporosis on quality of life and quality of life on osteoporosis: rationale and methodology for accurate assessment
Gonadal steroids and the pathogenesis of osteoporosis
Novel signals determining skeletal cell fate and function
Sex steroid hormones and bone formation
The effect of sex steroids on osteoclast function
Calcium and vitamin D: regulation of mineral homeostasis
Epidemiology
Genetic regulation of bone mass
Bone mineral acquisition during infancy and adolescence
Osteoporosis: influence of life-style
Postmenopausal osteoporosis and dental health
Diagnosis
Bone quality
Diagnosis: clinical, hormonal and biochemical evaluation
Advanced imaging assessment of bone quality
Quantitative ultrasonometry of bone in the management of postmenopausal women
Pharmacological prevention and treatment
Awareness of osteoporosis and related treatments
Intervention thresholds for osteoporosis
Vitamin D and calcium supplements
Estrogen dose response in bone density and bone histology
Effects of oral contraceptive preparation on bone health
Hormone replacement therapy
New physiologic approach to prevention of postmenopausal osteoporosis
Selective estrogen receptor modulators
Bisphosphonates in the management of osteoporosis
Phytoestrogens: food or drug?
Tibolone
Understanding the role of aromatizable androgens in bone-sparing
Specific aspects of selected therapies
Strontium ranelate: a new first-line treatment for patients with postmenopausal osteoporosis
Reconciling risks and benefits of hormone replacement therapy in a single outcome: the QALY approach
Prevent, treat and maintain: how to optimize the management of postmenopausal osteoporosis
Transdermal hormone therapy: effects on bone
Progestogens and bone
Effect of different dose options of continuous combined hormone therapy on bone and bone marker N-terminal propeptide of type I procollagen: results from a long-term study in Finnish postmenopausal women
The use of alendronate in osteoporosis treatment: 10-year experience