Springer, 2009. -663. - The reader will be introduced to various aspects of the fundamentals of nanotechnology based drug delivery systems and the application of these systems for the delivery of small molecules, proteins, peptides, oligonucleotides and genes. How these systems overcome challenges offered by biological barriers to drug absorption and drug targeting will also be described. This book is primarily designed to be a reference textbook on the application of nanotechnology in the development of drug delivery systems and to highlight some of the most exciting developments in this field. For this purpose, the reader is introduced to various aspects of the fundamentals of nanotechnologybased drug delivery systems and the application of these systems for the delivery of small molecules, proteins, peptides, oligonucleotides, and genes. How these systems overcome challenges offered by biological barriers to drug absorption and drug targeting is also highlighted. To best do this the text is divided into the following sections: Fundamentals of Nanotechnology in Drug Delivery; Biopharmaceutical, Physiological and Clinical Considerations for Nanotechnology in Drug Delivery; Nanotechnology for the Delivery of Small Molecules, Peptides, Proteins, and Nucleic Acids; and A Look to the Future of Nanotechnology in Drug Delivery.