Bhatt Deepak L.(ed.) Platelets in Cardiovascular Disease

Imperial College Press, 2008. — 234 p.The book provides a succinct overview of the critical role of platelets in cardiovascular medicine. Cardiovascular disease is the leading cause of mortality worldwide, and recent research has found that the platelet is central to the genesis of heart attacks and stroke as well as many of the complications of angioplasty and bypass surgery. An explosion of knowledge of the biology of platelets has established their important role in the formation of blood clots and, perhaps more intriguingly, their role as inflammatory cells.This growth in information has been paralleled by the development of several drugs that can interfere with platelet action and thereby improve patient outcomes. Indeed, several antiplatelet drugs already in development may ultimately lead to marked advances in both the treatment and prevention of cardiovascular disease. Drawing upon a panel of international experts, "Platelets in Cardiovascular Disease" delivers a concise yet thorough review of the major developments in antiplatelet therapy. Practicing clinicians as well as those involved in the development of new antithrombotic therapies will find the book interesting and useful.Platelet Biology: The Role of Platelets in Hemostasis, Thrombosis and Inflammation
Thromboxane Antagonists
Glycoprotein IIb/IIIa Inhibitors
ADP Receptor Antagonists
Monitoring Antiplatelet Therapy
Platelet Genomics
Future Strategies for the Development of Antiplatelet Drugs