Palomba Stefano (ed.) Infertility in Women with Polycystic Ovary Syndrome: Pathogenesis and Management

Springer, 2018. — 329 p.This book presents up-to-date knowledge on infertility in the context of polycystic ovary syndrome (PCOS) and provides clear evidence-based guidance on its treatment. The book opens by discussing anovulation, oocyte quality, and the endometrium in women with PCOS, infertility and subfertility cofactors, and the impact of PCOS phenotypes on fertility. All aspects of management are then thoroughly addressed. The available medical treatments for PCOS-related infertility – including antiestrogens, aromatase inhibitors, insulin-sensitizing drugs, and gonadotropins – are reviewed, and other potential therapeutic approaches, such as acupuncture and laparoscopic ovarian drilling, are assessed. Careful attention is also devoted to the role of lifestyle interventions. The use of controlled ovarian stimulation in infertile PCOS patients undergoing intrauterine insemination or in vitro fertilization is examined in detail, as are the benefits of in vitro maturation of oocytes. This book will be of value to all who are involved in the care of women with PCOS and related infertility issues.Diagnosis, Pathophysiology, and PathogenesisDiagnostic Criteria for PCOS
Anovulation in Women with PCOS
Oocyte Quality in PCOS
Endometrial Receptivity in PCOS
Infertility and Subfertility Cofactors in Women with PCOS
PCOS Phenotypes: Impact on Fertility
Follicle Excess and Abnormalities in Women with PCOS: Pathophysiology, Assessment and Clinical Role
Medical Treatments
Antiestrogens
Aromatase Inhibitors
Insulin-Sensitising Drugs
Gonadotrophins
Lifestyle Management and Other Treatment Approaches
Lifestyle Interventions and Natural and Assisted Reproduction in Patients with PCOS
Dietary Supplements, Phytotherapy and Chinese Herbal Medicine in PCOS
Laparoscopic Ovarian Drilling
Inositols
Acupuncture
Controlled Ovarian Stimulation and In Vitro Oocyte Maturation
Intrauterine Insemination
Controlled Ovarian Stimulation for In Vitro Fertilisation Cycles
In Vitro Oocyte Maturation
Integrated Strategies, Complications of Pregnancy, and Outlook
Integrated Strategies for Enhancement of Fertility in PCOS
Complications of Pregnancy
Conclusive Remarks and Future Perspectives