Lotvall Jan (ed.) Advances in Combination Therapy for Asthma and COPD

Wiley-Blackwell, 2012. — 1036 p.Aimed at specialists in respiratory medicine, this new book comprehensively reviews the variety of agents currently available for treatment of asthma, COPD, and other airway diseases and covers practical guidelines as well as challenges and complications in their use. Advances in Combination Therapy for Asthma and COPD is the first book to address the complexity of multi-agent therapy and deal with management issues in an integrated fashion. A review of currently available agents and their applications, as well as new therapies soon to become available are outlined. Advantages of combined therapies and additional considerations that arise from multi-agent programs are highlighted.Similarities and differences in the pathophysiology of asthma and COPD
Glucocorticoids: pharmacology and mechanisms
Inhaled corticosteroids: clinical effects in asthma and COPD
LABAs: pharmacology, mechanisms and interaction with anti–inflammatory treatments
Long– and ultra–long–acting 2–agonists
The safety of long–acting beta–agonists and the development of combination therapies for asthma and COPD
Inhaled combination therapy with glucocorticoids and long–acting 2–agonists in asthma and COPD, current and future perspectives
Novel anti–inflammatory treatments for asthma and COPD
Novel biologicals alone and in combination in asthma and allergy
Anti–infective treatments in asthma and COPD
Long–acting muscarinic antagonists in asthma and COPD
Phosphodiesterase inhibitors in obstructive lung disease
Biological therapies in development for COPD
Triple therapy in the management of COPD: inhaled steroid, long–acting anticholinergic and long–acting 2–agonist